<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12779

Description ATP-dependent DNA helicase
SequenceMEDDILEELLNVETELQEVQDQIKILLDRQEKLYARQSELKILLEECNASGSPADGGASVTVENWSGPFGWDSEADDIRFNVFGISTYRANQREIINAVMSGRDVLVIMAAGGGKSLCYQLPAILRDGVALVVSPLLSLIQDQVMGLSALGIPAYMLTSTTSKEDEKFIYRALEKGEGELKILYVTPEKVSKSKRFMSKLEKCHHGGRLSLIAIDEAHCCSQWGHDFRPDYKNLGILKTQFPSVPVVALTATATKKVQADLMEMLHISKCIKFVSTVNRPNLFYMVRDKSSVGKVVVDEIADFIRSSYPNNESGIVYCFSRKECEQVAEELCQRGISAGFYHADMDVGAREKVHLRWSSNKLQVIVGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPSECVLYYRPGDVPRQSSMVFYENAGLQNLYDMVRYCQSKRGCRRSAFFHHFAEPLQDCNGMCDNCAFGTELNEVDVTRQAKAIVSLLQEIQEKDQRATMLQLVDKVKVKYKESGSDLKKEETEQLIIQLILDRVLKEEFQHTPYATNAYVTIGPLWKQVLQGKRTVKLEICGGRKSNTGNIKSVKRNGSVSALEIKLDNLRKELSSTHGGIFPHAVLSTQQISLLSAQRPTSIEQLEKIIGKLKTEKYGKRILEQVEQYIESGQPDEDKRNEEECSENRAKKRLKTKKAPVLIESSEDEG
Length708
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.07
Grand average of hydropathy-0.380
Instability index49.08
Isoelectric point6.58
Molecular weight79603.16
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12779
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.69|      31|     138|     503|     534|       1
---------------------------------------------------------------------------
  503-  534 (45.80/32.23)	QRATMLQLVDKV..KVKYKESGSDLkKEETEQLI
  636-  668 (46.89/28.56)	QRPTSIEQLEKIigKLKTEKYGKRI.LEQVEQYI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.90|      46|     139|     268|     335|       2
---------------------------------------------------------------------------
  268-  328 (62.69/83.49)	SKCIkfvstvnrpnLFYMVRDKSSVGKVVVDEIADfIRSSYpnneSGIVYCFSRKECEQVA
  409-  454 (86.21/51.07)	SECV..........LYYRPGDVPRQSSMVFYENAG.LQNLY....DMVRYCQSKRGCRRSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.34|      69|     462|      83|     157|       3
---------------------------------------------------------------------------
   83-  157 (107.76/93.09)	FGISTYRANQREII....NAVMSGRDVLVIMAAGGGKSLCYQLPAILRDGValvVSPL...LSLIQDQvmgLSAL..GI.PAYML
  547-  625 (97.58/68.75)	FQHTPYATNAYVTIgplwKQVLQGKRTVKLEICGGRKSNTGNIKSVKRNGS...VSALeikLDNLRKE...LSSThgGIfPHAVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.51|      33|     155|      16|      69|       4
---------------------------------------------------------------------------
   37-   69 (59.60/68.88)	QSELKIL................LEECNASG..SPADGGASVTVENWSGPF
  177-  227 (48.91/21.46)	EGELKILyvtpekvskskrfmskLEKCHHGGrlSLIAIDEAHCCSQWGHDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.18|      19|     461|      14|      32|       5
---------------------------------------------------------------------------
   14-   32 (33.31/24.14)	TELQEV....QDQ.IKILLDR.QEK
  477-  501 (17.87/ 9.61)	TELNEVdvtrQAKaIVSLLQEiQEK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12779 with Med34 domain of Kingdom Viridiplantae
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