<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12772

Description pre-mRNA-processing protein 40A
SequenceMANNPQSSGTQPLRPPVVGSAGPQNYGPPMSMQFRPVVPMQQPQPFIPAASQQFRPVSQGISVSNVGTPPAQGQQLQFSQPTQQLPPRPGQPGSGPPSSQAIPMPYPQPNRSILSVSSQPQQNAQPMSGIGGMGMPLSSSYTFTISSYGQPQSNINTSTQYQPASQIHAPVVPAAGQPWLSSGSQSVPLVTPVQQNIQQPSITTAQVPVTTAQPSPAQQSSSDWQEHTSADGRRYYYNKKTRQSSWEKPVELMTPIERADASTVWKEFTTPEGRKYYYNKATKQSKWTMPDELKLAREQAEKAASQGIQSETTMASQTASTVTVSSVETPSAAANPLGATSAVTSIVASSPVPVTPVVAAINPLPVVSSGSQAVPVVPGAVTTSAVGVNSPAAAIATVPVSVPGGAGVPVAFASANNTATNSAENVSTQDVAASVDGASAQDLEEAKKGMAVAGKINITPVEEKTIDDEPLVYANKLEAKNAFKALLESANVESDWTWEQAMRVIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMKQKRAREEFTKMLEESKELTSSTRWSKAISMFEDDERFKAVERPRDREDLFENYLVELQKKERAKAQEEHKRNIMEYRQFLESCDFIKANSQWRKVQDRLEDDERCSRLEKIDRLEIFQEYIRDLEKEEEEQRKIQKEQLRRAERKNRDEFRKLMEEHVTAGTLTAKTHWRDYCMKVKDLPAYVAVSSNTSGSTPKDLFEDVSEELEKQYHDDKTRIKDAIKLGKISMASTWTIEDFKAAIAEHVGSPSISDINFKLVFDELLERIKEKEEKEAKKRQRLADDFSELLHSIKEITASSKWEESKPLFEDSQEYRSISDENFRREIFEEYIIHLQGKAKEKERKREEEKVKKEKEREEKEKRKEKERKEKEKEREREKGKERSKKDDTENENIDVTDIHVSKEDKKREKDKDRDKDRDKDKDRKHRKRHHSTADDVSSEKDEKEDSKKSRRHNSDRKKSRKHAYTPESDSESRHKRHKRDHRDGSRRNGAYEELEDGELGEDGEIR
Length1046
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.06
Grand average of hydropathy-1.042
Instability index59.56
Isoelectric point7.06
Molecular weight118308.41
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12772
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     147.85|      37|      38|     224|     260|       1
---------------------------------------------------------------------------
  181-  240 (41.61/20.41)	...SSGSQSVPLVTPVQQNIqqpsittaqvpvttaqpspaqqsssdWQEHTSADGRRYYYNKK
  241-  281 (65.80/36.49)	TRQSSWEKPVELMTPIERAD......................astvWKEFTTPEGRKYYYNKA
  282-  317 (40.44/19.63)	TKQSKWTMPDELKLAREQAE....................kaasqgIQSETT.......MASQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     444.61|      65|      65|     481|     545|       3
---------------------------------------------------------------------------
  481-  545 (98.96/68.89)	N..AF.KALLES.AN.VESDWT....WEQ.AMRVI........INDKRYGAL..KTLGERKQAFNEYL....GQRKKLEAEERRMKQK.R
  548-  613 (88.33/60.54)	E..EFtKMLEES.KE.LTSSTR....WSK.AISMF........EDDERFKAV..ERPRDREDLFENYL....VELQKKERAKAQEEHK.R
  614-  680 (80.58/54.46)	NimEY.RQFLES.CDfIKANSQ....WRK.VQDRL........EDDERCSRL..EKI.DRLEIFQEYI....RDLEKEEEEQRKIQKE.Q
  690-  756 (65.14/42.34)	D..EF.RKLMEE.HV.TAGTLTakthWRDyCMKV.........KDLPAYVAVssNTSGSTPKDLFEDV....SE..EL..EKQYHDDK.T
  760-  820 (55.11/34.46)	D..AI.K..LGK.IS.MASTWT....IED.FKAAIaehvgspsISDINF...........KLVFDELL.....ERIK.EKEEKEAKKRqR
  823-  879 (56.49/35.55)	D..DF.SELLHSiKE.ITASSK....WEE.SKPLF........EDSQEYRSI..SDENFRREIFEEYIihlqGKAK..............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.69|      34|      36|     937|     971|       4
---------------------------------------------------------------------------
  903-  932 (37.68/13.95)	.....KEKERKEKEKEREREKGKERSKKDDTENEN
  937-  971 (54.24/26.56)	DIHvSKEDKKREKDKDRDKDRDKDKDRKHRKRHHS
  975- 1008 (52.77/22.48)	DVS.SEKDEKEDSKKSRRHNSDRKKSRKHAYTPES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     206.55|      31|      31|      91|     121|       5
---------------------------------------------------------------------------
   29-   68 (32.64/14.46)	P..MSmqfrPVVPM.QQPQP..FIPAASQQfrPV........SQG.isvSnvG..T
   69-   96 (29.66/12.47)	P..PA....QGQQL.QF...........SQ..PTqqlpprpgQPG....S..G..P
   97-  135 (50.91/26.70)	P..SS....QAIPM.PYPQPNRSILSVSSQ..PQqnaqpmsgIGG....M..G..M
  136-  162 (21.81/ 7.22)	PlsSS....YTFTIsSYGQPQSNI.NTSTQ..YQ......................
  163-  178 (20.75/ 6.50)	P..AS....Q.IHA.P.......VVPAAGQ..P.......................
  353-  390 (25.09/ 9.41)	P..VT....PVVAA.INPLP...VVSSGSQavPV........VPGavttSavGvnS
  391-  408 (25.69/ 9.81)	P..AA....AIATV.PV...........SV..P..........GG....A..G..V
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12772 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKEKERKREEEKVKKEKEREEKEKRKEKERKEKEKEREREKGKERSKKDDTENENIDVTDIHVSKEDKKREKDKDRDKDRDKDKDRKHRKRHHSTADDVSSEKDEKEDSKKSRRHNSDRKKSRKHAYTPESDSESRHKRHKRDHRDGSRRNGAYEELEDGELGEDGEIR
2) MANNPQSSGTQPLRPPVVGSAGPQNYGPPMSMQFRPVVPMQQPQPFIPAASQQFRPVSQGISVSNVGTPPAQGQQLQFSQPTQQLPPRPGQPGSGPPSSQAIPMPYPQPNRSILSVSSQPQQNAQPMSGIGGMGMP
3) SYTFTISSYGQPQSNINTSTQYQPASQIHAPVVPAAGQPWLSSGSQSVPLVTPVQQNIQQPSITTAQVPVTTAQPSPAQQSSSDWQEHTSADGRRYYYNKKT
4) TMPDELKLAREQAEKAASQGIQSETTMASQTASTVTVSSVETPSAAAN
878
1
140
288
1046
136
241
335










Molecular Recognition Features






MoRF SequenceStartStop




1) AYEELEDGEL
2) GRKYYY
3) HRKRHH
1030
273
965
1039
278
970