Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAATSATYPPPPPYYRLYKDYLQNPKLASEPPPPIQGTYMLYGGTYTTDDVLPSLEEQGVRQLYPKGPNIDFKKELRSLNRELQLHILELADVLVERPSQYARRVEDISLIFKNLHHLLNSLRPHQARATLIHILELQIQRRKQAVEDIRRRREEAQRLLKESLGTLDGH |
Length | 170 |
Position | Middle |
Organism | Nelumbo nucifera (Sacred lotus) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.658 |
Instability index | 75.32 |
Isoelectric point | 9.10 |
Molecular weight | 19760.41 |
Publications | PubMed=23663246 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP12768 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 54.90| 13| 21| 6| 18| 1 --------------------------------------------------------------------------- 6- 18 (30.61/16.88) ATYPPPP..PYYRLY 28- 42 (24.28/12.08) ASEPPPPiqGTYMLY --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 112.74| 38| 45| 76| 114| 2 --------------------------------------------------------------------------- 50- 80 (27.78/14.57) ...........DVLPSLEEQGVRQLypKGPNIDFKKeLRSLN 81- 120 (57.27/42.08) RELQLHILELaDVLVERPSQYARRV..EDISLIFKNlHHLLN 128- 149 (27.69/14.81) RATLIHILEL.QI..QRRKQ...AV..EDI............ --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) TYMLYGGTY 2) TYPPPPPYYRLYKDYLQNPKLA | 38 7 | 46 28 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab