<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12764

Description ATP-dependent DNA helicase Q-like 4A isoform X1
SequenceMTNGKFSSGNNSSKDFKLDAKLPRVNWSHHANAHHNFSCQNQFLSSNFLFSLPTQKSHVEEALCAGSMAFQIQNIQRLQSSHIQKAWEALSSVNMACRNYLKPGITVPIVQNIGTDHLPLKRSDSKNISKATTLWRSSDITCKFSESSTFQNLQPHQNLNYCGVRVGESGDSLLESRNSASDTGVGVRLSEDKEASPINGSHANIRGGSSGIHTLHKQDNPEKEFGDHFADDIGDDDILENIDVDQIVLQYQATCTPQSSTSKLPSTTFLSNNNNTVPDETYFPPELCTICNHGFKVGICPEAANHLQEMKDTLIEISNELLDNFNFLSPVQIESLRQDRLQLNKKIQQLDKYLYFKERDEERQKSNFSASTTRGLQYETPPHGAYTMNHSGFDARINTSSEPGGFGKGISSLISFSSIDGFGASLGPVEREAYVPKIIEVNYIEGSNDKRWSSRDFSWTRKLEENNKKVFGNHSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPALICPGITLVVSPLVSLIQDQIMHLVQANIPAAYLSANMEWAEQQEILRELNSDYSRYKLLYVTPEKIAKSDVLLRHLESLHARSLLARIVVDEAHCVSQWGHDFRPDYQGLGILKQKFPNTPVLALTATATASVKEDVVQALGLVNCVVFRQSFNRQNLRYSVIPKTKRCLEDIDKFIKENHFDECGIIYCLSRMDCEKVADKLQEFGHKAAFYHGSMDSQQRTFVQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQPSSCLLYYSYSDYIRVKHMISQGVIEQSPLALGSGRISGTNAGRILETNVENLLRMVSYCENDVDCRRLLQLVHFGEKFDPANCGKTCDNCSKAVNYVDKDVTDIAKHLVELVKSTGQQHSSSHILEVYRGSMCQNVKKYRHDRLSVHGVGKSLPKGFASRILRHLVIEDILTEDVKKSDIYGSVSSILKINESKAYNLCFGGRKIILRFPDSTKKSMMSKSGAAPAKDPLLSGMGSPQNDTPAQPQNEVDLNLSAKLYSSLRMLRTTLVREAGEGVMAYHIFLNTTLQQISRRIPRTKEELLDISGIGKAKVNKYGDRLLETIESTIREHYKLEKDSSGDKDSTETIKRRRNSTGISDARIEEDDDFTFTVASDLSKGRPAKQGRKKGTGPKDFSLPRYDDEQFLDADLDLEYNYNDKDNGSYEKADQNSEGRVLPSWAIP
Length1233
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy-0.517
Instability index47.07
Isoelectric point6.87
Molecular weight138153.09
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12764
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     702.50|     232|     442|     330|     590|       1
---------------------------------------------------------------------------
  330-  590 (343.96/292.14)	PVQIESLRQDRLQLNKKIQQLDKYLYFKERDEERQKSNFSasttRGLQYETP.PHGAYTMnhSGFDA.RI.NTSSEpggfgkGISSLISF..SSID........GFGASLGPVEREAYVPKIIE.VNYIegsnDKrwSSRDFSwtRKLEENNKKVFGNHSfRPNQREVINATMsgCDVF......VLMPTGGGKSLTYQLPALICPGITL..VVSPLV..SLIQDQIMHLVQANIPAAYlsaNMEWAEQQEILRElnSDYSRYKLLYVTPEKIAKsDVLLRHLES
  773- 1028 (358.54/226.83)	PKSIEGYHQECGRAGRDGQPSSCLLYYSYSDYIRVKHMIS....QGVIEQSPlALGSGRI..SGTNAgRIlETNVE......NLLRMVSYceNDVDcrrllqlvHFGEKFDPANCGKTCDNCSKaVNYV....DK..DVTDIA..KHLVELVKSTGQQHS.SSHILEVYRGSM..CQNVkkyrhdRLSVHGVGKSLPKGFASRILRHLVIedILTEDVkkSDIYGSVSSILKINESKAY...NLCFGGRKIILRF..PDSTKKSMMSKSGAAPAK.DPLLSGMGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     363.91|     112|     408|     194|     310|       2
---------------------------------------------------------------------------
  194-  310 (177.41/138.38)	EASPINGSHANIRGGSSGIHTLhKQDNPEKEFGDHFADDIG..DDDILENIDVDQIVLQYQATCTPQSSTSKLPSTT.FLSNNNNTVpDETYFppELCTICNHGFKVGiCPEAANHLQEM
  604-  718 (186.49/123.59)	EAHCVSQWGHDFRPDYQGLGIL.KQKFPNTPVLALTATATAsvKEDVVQALGLVNCVVFRQSFNRQNLRYSVIPKTKrCLEDIDKFI.KENHF..DECGIIYCLSRMD.CEKVADKLQEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     325.15|     108|    1000|      40|     150|       3
---------------------------------------------------------------------------
   40-  150 (179.48/152.89)	QNQF...LSSNFLFSLPTQKSH.VEEAlCAGSMAFQIQNIQRLQ..SSHIQKAWEAL...SSVNMACRNylKPG.ITVPIVQNIGTDHLPLKRSDSKNISKATTLWR...SSDIT.CKFSESSTF
 1038- 1159 (145.67/112.34)	QNEVdlnLSAKLYSSLRMLRTTlVREA.GEGVMAYHIFLNTTLQqiSRRIPRTKEELldiSGIGKAKVN..KYGdRLLETIESTIREHYKLEKDSSGDKDSTETIKRrrnSTGISdARIEEDDDF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12764 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HYKLEKDSSGDKDSTETIKRRRNSTGISDA
2) LLESRNSASDTGVGVRLSEDKEASPINGSHANIRGGSSGIHTLHKQDNPEKEFGDHFA
3) MMSKSGAAPAKDPLLSGMGSPQNDTPAQPQNEV
1122
173
1009
1151
230
1041










Molecular Recognition Features






MoRF SequenceStartStop




1) EGRVLPSWAIP
2) PKDFSLPRYDDEQFLDADLDLEYNYND
3) TIKRRRN
1223
1183
1138
1233
1209
1144