<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12758

Description luminal-binding protein 5
SequenceMDGVWKKRGSLIVLGIVLFGCLSAFAIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAAVNAERTIFDVKRLIGRKFEDKEVQKDMKLVPYKIVNKDGKPYIQVKIKDGETKVFSPEEISAMVLXKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGIIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRIMEYFIKLIKKKHNKDISKDNRALGKLRRECERAKRALSSQHQVRVEIESLYEGLDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLEKHQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGSILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRMLGKFDLSGIPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGRSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKEKIDARNSLETYIYNLKNQISDKDKLADKLESEEKDKIETAVKEALEWLDDNQSAEKEDYDEKLKEVEAVCNPIIAAVYQRTGGAPGGASDGGDDDSHDEL
Length666
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.06
Grand average of hydropathy-0.445
Instability index29.22
Isoelectric point5.16
Molecular weight73375.42
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12758
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      26|     232|     242|       1
---------------------------------------------------------------------------
  232-  242 (20.46/11.63)	LGGGTFDVSIL
  260-  270 (21.85/12.92)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.47|      34|     239|     383|     424|       3
---------------------------------------------------------------------------
  389-  424 (55.03/52.33)	KEPNKGVNPDEAVAYG...AAVQGSilSGEGGDETKDIL
  630-  666 (56.44/31.86)	KEVEAVCNPIIAAVYQrtgGAPGGA..SDGGDDDSHDEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.60|      20|      22|     492|     513|       6
---------------------------------------------------------------------------
  494-  513 (36.94/22.93)	SGI...PPAPRGTPQIE.VTFEVD
  515-  538 (24.66/ 7.94)	NGIlnvKAEDKGTGRSEkITITND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.05|      17|      26|       7|      25|       9
---------------------------------------------------------------------------
    7-   25 (25.87/25.63)	KRGSliVLGIVL...FGCLSAF
   34-   53 (26.18/18.16)	KLGT..VIGIDLgttYSCVGVY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12758 with Med37 domain of Kingdom Viridiplantae
Unable to open file!