<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12757

Description mediator of RNA polymerase II transcription subunit 23
SequenceMDQNQRTPRPYQFHPARTAIIDLFNLYLGRSSRQKSEEPIREPPNKTQKRVTALNRDLPPRNEQFILDFEQLQGQFPDQEQLRAVTESVLISLVVQCSSHAPRAEFILFALRNLCSIGYVNWDSFLPSLLSSVSTAEASIGQGQTMNSVSSTSQSAMVASSSTIPNSSNFQPSNPASPMPSINAIGSPAQSATEPSSFTTLSPVKSSDVSCTGQQNISRSNPSVRDNVISCLRQLSCKIILAGLESNLKPVTHAQIFSHMLNWLANWDQRQQGVNECDGAKAWKPDRVLTEWLHSCLDVIWLLVEEDKCRVPFYELLRSNFQFIENIPDDEALFTLILEIHRRRDMVAMHMQMLDQHLHCPTFGTHRYLSQAYQSVSGESVANMRCLPITYPSVLGEPLHGEDLATSIQRGSLDWERAVRCLRHALHSTPSPDWWRRVVHVAPSYRPQAQQGLTPSAVFSAEMICEATIDRIMELLKLTHSEAHCWQEWVTFSDLFFYLMKNGCIDFVDFIDKLSSRITKADLQTLRTNHVTWLLAQIIRIEIVTNVLNNDPRKVEVTRKILSFHKEDRSSDPNNVNPQCILLDFISSSQTLRIWSYNTSIREYLNHEQLTKGKQIDEWWKQVTKGERMLDYMNLDDRSIGMFWVLSHTMAQAASEAVLNWLTSAGVTELIPGSNVPSGERVMAMRESSPLPMSLLSGISINVCLKLTHQIEESLFFGQVVPSISMVETYVRLLLIAPHSCFRPHFTNLAQRNPSILNKPGVSLLLLEILNYRLLPLYRYHGKSKTLMYDVTKLISMLKSKRGDHRLFRLAENLCMNLILSLRDFFLVKKDLKGPSEFTETLNRVTIINLAITVKTRGIAEVEHMVFFQPVLDQIMGASQHMWSEKTLRFFPPLLRDALMGRMDKRGQTIQTWQQAEQTVLNQCKQLLSPSAADSYLMTYVNHSFPQHRQYLCAGAWILMFGHPENINSANLGRVLREFSPEEVTANIYTLVDVLLHHIHKELQIGHLLQDLLLKTTTNLSFLIFTHELIPLDILLLALIDRDDDPHALRIVISLLDRQELQQRVKMFCMNRGLPEHWHHSGIFKRVELQKALGNHLSWKDRYPTFFDDIAARLLPVIPLIIYRLIENDATDTADRVLAIYSTLLAYHPLRFTFVRDILAYFYSHLPNKLIVRILHVLDLSKIPFSESFPQHISSSNPVLCPPLDYFATLLMGIVNNVIPPLTSKSRSGSLGDASNNSSRVPQNKPLASSQSGPTNASEGQKAFYQNQDPGTYTQLVLETAAIEILSLPGPASQIVSSLLQIIMHVQPTLIQSSNCLQGSSSGVGQSSVLPTSPSGGSTDSLSTSRSATTASGLNYSNFVSKSGYTCQQLSCLLIQACGLLLAQLPPDFHNQLYLESARIIKESWWLTDGKRPLRELDSAVGYALLDPTWAAQDSTSTAIGNIVALLHAFFSNLPLEWLEGTHAIIKNLRPLTSVAMLRIVFRIMGPLLPRLSCAKQPFVKTLALLFHAMADVFGKNTQPSTPTEASEIADLIDFLHHAVLYEGQGGPVQSNSKPKVDILTLCGKTMEALRPDLQHLLSHLKTDPNSSIYAATHPKLAQNLS
Length1602
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy-0.117
Instability index48.80
Isoelectric point7.10
Molecular weight180290.11
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12757
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     355.03|     116|     183|    1262|    1393|       1
---------------------------------------------------------------------------
 1262- 1393 (169.90/150.35)	KAFYQNQdPGTYtqlvLE.TAAIeILSLpGPASQIvsSLLQIIMHVQPTLIQSSNC...........LQGSSSGVGQSSVLPTSPSggstdslSTSRSATTASGLNYSNFVSKSGYTCQQLS...CLLIQACGLLLAQLPPDFHNQL
 1448- 1578 (185.13/119.78)	HAFFSNL.PLEW....LEgTHAI.IKNL.RPLTSV..AMLRIVFRIMGPLLPRLSCakqpfvktlalLFHAMADVFGKNTQPSTPT.......EASEIADLIDFLHHAVLYEGQGGPVQSNSkpkVDILTLCGKTMEALRPDLQHLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.01|      28|     184|     403|     438|       2
---------------------------------------------------------------------------
  403-  434 (41.23/45.80)	DLatsIQRGSLDwERAV...RCLRHALHSTPSP...DW
  628-  661 (40.77/19.59)	RM...LDYMNLD.DRSIgmfWVLSHTMAQAASEavlNW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     235.23|      78|     564|      99|     191|       5
---------------------------------------------------------------------------
   99-  191 (111.68/109.95)	SHAPRAEFILfALRNlcsigyvnwDSFLP.SLLSSVS.........TAEASIGQGQTMNSVSSTsqSAMVASSSTIPNSSnFQP..SNPASPMPSInaIGSPAQS
  674-  763 (123.55/78.15)	SNVPSGERVM.AMRE.........SSPLPmSLLSGISinvclklthQIEESLFFGQVVPSISMV..ETYVRLLLIAPHSC.FRPhfTNLAQRNPSI..LNKPGVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.08|      36|     472|     448|     490|      10
---------------------------------------------------------------------------
  448-  490 (55.80/60.76)	QAQQGLTPSAVFSAEMiceATIDRIMEllklTHSEAHCWQEWV
  923-  958 (68.28/51.15)	QCKQLLSPSAADSYLM...TYVNHSFP....QHRQYLCAGAWI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12757 with Med23 domain of Kingdom Viridiplantae
Unable to open file!