<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12756

Description ATP-dependent DNA helicase Q-like 4A isoform X2
SequenceMAFQIQNIQRLQSSHIQKAWEALSSVNMACRNYLKPGITVPIVQNIGTDHLPLKRSDSKNISKATTLWRSSDITCKFSESSTFQNLQPHQNLNYCGVRVGESGDSLLESRNSASDTGVGVRLSEDKEASPINGSHANIRGGSSGIHTLHKQDNPEKEFGDHFADDIGDDDILENIDVDQIVLQYQATCTPQSSTSKLPSTTFLSNNNNTVPDETYFPPELCTICNHGFKVGICPEAANHLQEMKDTLIEISNELLDNFNFLSPVQIESLRQDRLQLNKKIQQLDKYLYFKERDEERQKSNFSASTTRGLQYETPPHGAYTMNHSGFDARINTSSEPGGFGKGISSLISFSSIDGFGASLGPVEREAYVPKIIEVNYIEGSNDKRWSSRDFSWTRKLEENNKKVFGNHSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPALICPGITLVVSPLVSLIQDQIMHLVQANIPAAYLSANMEWAEQQEILRELNSDYSRYKLLYVTPEKIAKSDVLLRHLESLHARSLLARIVVDEAHCVSQWGHDFRPDYQGLGILKQKFPNTPVLALTATATASVKEDVVQALGLVNCVVFRQSFNRQNLRYSVIPKTKRCLEDIDKFIKENHFDECGIIYCLSRMDCEKVADKLQEFGHKAAFYHGSMDSQQRTFVQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQPSSCLLYYSYSDYIRVKHMISQGVIEQSPLALGSGRISGTNAGRILETNVENLLRMVSYCENDVDCRRLLQLVHFGEKFDPANCGKTCDNCSKAVNYVDKDVTDIAKHLVELVKSTGQQHSSSHILEVYRGSMCQNVKKYRHDRLSVHGVGKSLPKGFASRILRHLVIEDILTEDVKKSDIYGSVSSILKINESKAYNLCFGGRKIILRFPDSTKKSMMSKSGAAPAKDPLLSGMGSPQNDTPAQPQNEVDLNLSAKLYSSLRMLRTTLVREAGEGVMAYHIFLNTTLQQISRRIPRTKEELLDISGIGKAKVNKYGDRLLETIESTIREHYKLEKDSSGDKDSTETIKRRRNSTGISDARIEEDDDFTFTVASDLSKGRPAKQGRKKGTGPKDFSLPRYDDEQFLDADLDLEYNYNDKDNGSYEKADQNSEGRVLPSWAIP
Length1166
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.07
Grand average of hydropathy-0.509
Instability index49.12
Isoelectric point6.65
Molecular weight130719.96
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12756
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.72|      58|     216|      77|     144|       1
---------------------------------------------------------------------------
   77-  144 (82.08/77.04)	FSESSTfQNLQpHQNLNYCGVRVGESGdslLESR.NSASDT.GVGVRLSEDKEASPINGShanirGGSSG
  301-  360 (96.65/59.60)	FSASTT.RGLQ.YETPPHGAYTMNHSG...FDARiNTSSEPgGFGKGISSLISFSSIDGF.....GASLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     227.71|      63|     216|     817|     881|       2
---------------------------------------------------------------------------
  819-  881 (103.88/77.85)	VN.YVDKDVTDIAKHLVE...LVKSTGQQHSSSHI.LEVYRGSMCQNVKKYRHDRLSVHGVGKSLPKG
  993- 1035 (39.73/23.08)	.....................LVREAGEGVMAYHIfLNTTLQQISRRIPRTKEELLDISGIGKA....
 1037- 1103 (84.11/55.59)	VNkYGDRLLETIESTIREhykLEKDSSGDKDSTET.IKRRRNSTGISDARIEEDDDFTFTVASDLSKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.54|      16|     406|      36|      51|       3
---------------------------------------------------------------------------
   36-   51 (31.20/18.22)	PGITV...PIVQNIGTD..HL
  448-  468 (20.33/ 9.64)	PGITLvvsPLVSLIQDQimHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     227.94|      80|     406|     488|     577|       4
---------------------------------------------------------------------------
  488-  577 (117.23/120.86)	QEILRE..LNSD.Y.SRYKLLYVTPEK.....IAKSDVLLRHLESLHaRSLLARIVVDEAhcvsqwgHDfrPDYQGLGILKQKFPNTPV....LALTATATAS
  893-  985 (110.70/83.38)	EDILTEdvKKSDiYgSVSSILKINESKaynlcFGGRKIILRFPDSTK.KSMMSKSGAAPA.......KD..PLLSGMGSPQNDTPAQPQnevdLNLSAKLYSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.61|      12|     212|     394|     409|       5
---------------------------------------------------------------------------
  151-  162 (24.64/10.20)	QDNPEKEFGDH.F
  397-  409 (18.97/10.54)	EENNKKVFGNHsF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.47|      45|     405|     195|     243|       7
---------------------------------------------------------------------------
  195-  243 (68.59/51.43)	SKLPSTT.FLSNNNNTVpDETYFppELCTICNHGFKVGiCPEAANHLQEM
  606-  651 (76.88/42.08)	SVIPKTKrCLEDIDKFI.KENHF..DECGIIYCLSRMD.CEKVADKLQEF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12756 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HYKLEKDSSGDKDSTETIKRRRNSTGISDA
2) MMSKSGAAPAKDPLLSGMGSPQNDTPAQPQNEV
3) SLLESRNSASDTGVGVRLSEDKEASPINGSHANIRGGSSGIHTLHKQDNPEKEFGDHFA
1055
942
105
1084
974
163










Molecular Recognition Features






MoRF SequenceStartStop




1) EGRVLPSWAIP
2) PKDFSLPRYDDEQFLDADLDLEYNYND
3) TIKRRRN
1156
1116
1071
1166
1142
1077