<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12746

Description luminal-binding protein 4-like
SequenceMGAKYRATALLVLFAMEFLLGLAVASEESPKLGTVIGIDLGTTYSCVGVYRNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQASLNAERTIFDVKRLIGRKFDDPEVQRDIKFLPYKVVNKDGKPYIQVKIRDGETKVFSPEEISAMILGKMKETAEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVYDLGGGTFDVSILTIDNGVFEVLATSGDTHLGGEDFDHRVMDYFIKLIKKKYNKDISKDNKALGKLRRECERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNMDLFKKTMGPVKKALEDAGLKKTDIHEIVLVGGSTRIPKVQQLLKEMFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGEETKDILLLDVAPLSLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYEDQQTTVSIKVYEGERSLTKDCRELGRFDLSGIPPAPRGVPQIEVTFEVDANGILHVRAEDKAAKKSESITITNDKGRLSQEEIERMVKEAEEFAEEDRKVKEKIDARNKLETYVYNMKSTINDKDKLSDKIDSDDKEKIESTLKEALEWLDDNQSAEKDDYEEKLKEVEAVCNPIIKQVYEKSGGNSSGSGDEDEANDEL
Length661
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.06
Grand average of hydropathy-0.463
Instability index31.42
Isoelectric point5.14
Molecular weight73139.10
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12746
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.43|      20|      26|     560|     584|       1
---------------------------------------------------------------------------
  577-  598 (27.73/21.60)	NMKSTIND......kdKLSDKIDSDDK.E
  599-  627 (18.70/ 8.25)	KIESTLKEalewlddnQSAEKDDYEEKlK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.89|      15|      15|     183|     197|       2
---------------------------------------------------------------------------
  183-  197 (24.71/15.51)	AQRQATKDAGVIA.GL
  200-  215 (20.18/11.43)	ARIINEPTAAAIAyGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.60|      13|     168|     101|     119|       3
---------------------------------------------------------------------------
   78-   90 (20.95/ 9.31)	RLIG......EAAKNQASL
  101-  119 (15.65/18.69)	RLIGrkfddpEVQRDIKFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.47|      29|     168|     216|     276|       4
---------------------------------------------------------------------------
  218-  249 (40.94/71.35)	KGGE..KNILVYDLggGTFDVSILTIdNGVFEVL
  412-  442 (44.53/10.24)	EGGEetKDILLLDV..APLSLGIETV.GGVMTKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.96|      22|     168|     351|     392|       5
---------------------------------------------------------------------------
  327-  349 (32.47/33.75)	TR.ARFEELNMDLFKKTMgPVKKA
  370-  392 (33.49/11.79)	TRiPKVQQLLKEMFDGKE.PNKGV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12746 with Med37 domain of Kingdom Viridiplantae
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