<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12739

Description mediator of RNA polymerase II transcription subunit 33A isoform X1
SequenceMAASVQTTLWDSVVELTKCAQDKGSDPLLWAIQLSSSLNSAGVYLPSTEVAHILVSHICWGNNVSIAWKFLERALAVKIAPPMLVLALLSCRALPSRRSRPTAYRLYMELLKRHAFSFASQINGPNWQKTMKSIDDVLHLSQIFGLQACEPGVLVVEFVFSIVWQLLDATLDDEGLLEMTPEKESKWSTRQQDMEIDGHDSFDEKRTEHQDRLRKANTVMAVELIGQFLQNKITSKLLYLARQNMPLHWGSFIQRLQLLGTNSMALKSSKISPEALVQFSSDTCKILSRECKTSTQQEFHAVMASRSMTSSAGKCFGASQSSLWLPLDLFLEDSMDGSQVAVTSAIETLTVYTGLVKSLQAVNGTTWHDAFLGLWIAALRHVQRERDPIEGPVPRLDTRLCMLFSVTTLAIADIIEEEEAALIDETECSPNNQRKEKQVAGKRHKDLVSSLQILGDYEGLLTPPQSVVSVANQAAVKAMMFVSGVPVGSGYFECISMNDMPLNCSGNLRHLIVEACIARNLLDTSAYFWPGYVNRRINQIPHSMPAQVPGWSSLMKGAPLTSSMINALVSSPASSLAELEKIFDIAVNGSDDEKISAANILCGASLIRGWNIQEHTIHFVIRLLSPPVPADYSGSDSHLIGHAPMLNTLLVGIASVDCVQIFSLHGLVPQLAGALMPICEVFGSCVPNVSWTLTTGEEISAHAVFSNAFILLLRLWRFNHPPLEHVVGDVPPVGSQLTPEYLLLVRNSQLASSGINSKDRNKIRRQSTATNLSSVQPIFVDSFPKLKLWYRQHQACIASTLSGPVHGTPVHQIVDGLLNMVFRKMNKGSQSLTTGTSGSSTSSGPGNDDATLKPKLPAWDILEAVPFVIDAALTACSHGRLSPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPAFMNGTDWPSPAANLCNVEEQIKRILAATGVDVPSLAAGGTAPATLPLPLAAFVSFTITFKLDRASERSLNLAGPALESLSAGCPWPCMPIVASLWAQKVKRWSDFLIFSASRTVFHHNSDAVVQLLKSCFTATLGLNSTPLSSNGGVGALLGHGFGSHFYGGFSPVAPGILYLRVYRSIRDIMFMTEEILSLLMFSVREIVGDGLLRERMEKVKKTKNGMRYGQVSLAAAMTRVKLAALLGASFVWLSGGLGLVQSLIKETIPSWFISGHGSEQEGGCEGIVAMLRGYALAYFAVICGTFAWGVDSTTSASKRRAKILRAHMEFLASVLDGKVSLGCDWATWRAYVSGFVSLMVGCTPTWVLEVEVDVLKRLSKGLRQWNEEELALALLGRGGAGAMGAAAQLIVESEI
Length1329
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy0.134
Instability index44.51
Isoelectric point6.79
Molecular weight144529.18
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12739
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     641.34|     228|     272|     660|     931|       1
---------------------------------------------------------------------------
  514-  645 (106.65/60.35)	.......................................................................................................................................................EACIArNLLDTSAYFWP............GYVN....RRINQIPHSMPAQVPGwSSLMKGAPLTSSMINALVssPASSLAE.LEKIFDIAV........................................NGSDDEKISAANILCG....................ASLIRG.WniqehtihfvirllsppvpadysgSDSHLIG...HAPM
  660-  931 (342.56/351.57)	QIFSLHGL.VPQL.AGALMPICEVFgSCVPNVSWTLTtgeeisahavfsnaFIL...LLRLWRFNHPPLEHVVGDVP....PVGSQLTPEYlllV.RNSQLAssgINSKDRNKIRRQSTATN..LSSvqpIF.....VDSFPklklwyRQHQACIA.STLSGPVHGTPVH......QIVDGLLNM.VFRKMNKGSQSLTTGTSG.SSTSSGPGNDDATLKPKL..PAWDILEaVPFVIDAAL........................................TACSHGRLSPRELATGLKdLADFLPASLativsyfsAEVTRGvW........................KPAFMNGtdwPSPA
  943- 1164 (192.13/129.26)	RILAATGVdVPSLaAGGTAPATLPL.PLAAFVSFTIT..............FKLdraSERSLNLAGPALESLSAGCPwpcmPIVASLWAQK...VkRWSDFL...IFSASRTVFHHNSDAVVqlLKS...CFtatlgLNSTP......LSSNGGVG.ALLG...HGFGSHfyggfsPVAPGILYLrVYR.....................................................sirdimfmteeilsllmfsvreivgdgllrermekvkktkNGMRYGQVSLAAAMTRVK.LAALLGASF......................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     164.93|      53|     911|     309|     367|       2
---------------------------------------------------------------------------
  309-  367 (72.10/61.11)	TSSAGKcfgASQSSLWLPLDlFLEDSMDGsQVAVTSAIETLTVY.TGLVkSLQAVNGTTW
 1227- 1280 (92.83/54.49)	TTSASK...RRAKILRAHME.FLASVLDG.KVSLGCDWATWRAYvSGFV.SLMVGCTPTW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.71|      60|     190|      34|     100|       3
---------------------------------------------------------------------------
   34-  100 (90.40/71.77)	LSSSLNSAGVYLPSTEVAhilvshICWGNNVSIAWKFLERALAV...KIAPPMLV.LALLSCRALpSRRSR
  229-  292 (93.31/56.78)	LQNKITSKLLYLARQNMP......LHWGSFIQRLQLLGTNSMALkssKISPEALVqFSSDTCKIL.SRECK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12739 with Med33 domain of Kingdom Viridiplantae
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