<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12729

Description mediator of RNA polymerase II transcription subunit 33A isoform X3
SequenceMAASVQTTLWDSVVELTKCAQDKGSDPLLWAIQLSSSLNSAGVYLPSTEVAHILVSHICWGNNVSIAWKFLERALAVKIAPPMLVLALLSCRALPSRRSRPTAYRLYMELLKRHAFSFASQINGPNWQKPLHWGSFIQRLQLLGTNSMALKSSKISPEALVQFSSDTCKILSRECKTSTQQEFHAVMASRSMTSSAGKCFGASQSSLWLPLDLFLEDSMDGSQVAVTSAIETLTVYTGLVKSLQAVNGTTWHDAFLGLWIAALRHVQRERDPIEGPVPRLDTRLCMLFSVTTLAIADIIEEEEAALIDETECSPNNQRKEKQVAGKRHKDLVSSLQILGDYEGLLTPPQSVVSVANQAAVKAMMFVSGVPVGSGYFECISMNDMPLNCSGNLRHLIVEACIARNLLDTSAYFWPGYVNRRINQIPHSMPAQVPGWSSLMKGAPLTSSMINALVSSPASSLAELEKIFDIAVNGSDDEKISAANILCGASLIRGWNIQEHTIHFVIRLLSPPVPADYSGSDSHLIGHAPMLNTLLVGIASVDCVQIFSLHGLVPQLAGALMPICEVFGSCVPNVSWTLTTGEEISAHAVFSNAFILLLRLWRFNHPPLEHVVGDVPPVGSQLTPEYLLLVRNSQLASSGINSKDRNKIRRQSTATNLSSVQPIFVDSFPKLKLWYRQHQACIASTLSGPVHGTPVHQIVDGLLNMVFRKMNKGSQSLTTGTSGSSTSSGPGNDDATLKPKLPAWDILEAVPFVIDAALTACSHGRLSPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPAFMNGTDWPSPAANLCNVEEQIKRILAATGVDVPSLAAGGTAPATLPLPLAAFVSFTITFKLDRASERSLNLAGPALESLSAGCPWPCMPIVASLWAQKVKRWSDFLIFSASRTVFHHNSDAVVQLLKSCFTATLGLNSTPLSSNGGVGALLGHGFGSHFYGGFSPVAPGILYLRVYRSIRDIMFMTEEILSLLMFSVREIVGDGLLRERMEKVKKTKNGMRYGQVSLAAAMTRVKLAALLGASFVWLSGGLGLVQSLIKETIPSWFISGHGSEQEGGCEGIVAMLRGYALAYFAVICGTFAWGVDSTTSASKRRAKILRAHMEFLASVLDGKVSLGCDWATWRAYVSGFVSLMVGCTPTWVLEVEVDVLKRLSKGLRQWNEEELALALLGRGGAGAMGAAAQLIVESEI
Length1213
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy0.178
Instability index44.26
Isoelectric point8.06
Molecular weight131150.05
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12729
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     185.19|      57|      72|     667|     738|       1
---------------------------------------------------------------------------
  399-  441 (58.28/30.44)	.............ACIArNLLDTSAYF..WP......GYVN...RRINQIPHSMPAQVPGwSSLMKG
  668-  728 (92.94/92.72)	PKLKLW..YRQHQACIA.STLSGPVHG..TPvHQIVDGLLNmvfRKMNKGSQSLTTGTSG.SSTSSG
  738-  774 (33.97/10.46)	PKLPAWdiLEAVPFVID.AALTACSHGrlSP.RELATGL............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     166.00|      53|      75|      78|     133|       2
---------------------------------------------------------------------------
   78-  133 (81.22/70.31)	KIAPPMLV.LALLSCRALpSRRSRPTAYRLYMELL.KRHAFSFASQINGPNwQKPLhW
  154-  208 (84.78/56.25)	KISPEALVqFSSDTCKIL.SRECKTSTQQEFHAVMaSRSMTSSAGKCFGAS.QSSL.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.50|      27|      42|     826|     855|       3
---------------------------------------------------------------------------
  799-  832 (41.22/24.58)	GVWKPAFMNGTDWPS....PAAN......lcnveeqiKRILAAT
  833-  876 (29.74/24.23)	GVDVPSLAAGGTAPAtlpLPLAAfvsftitfkldrasERSLNLA
  877-  905 (30.54/15.97)	GPALESLSAGCPWPC...MPIVA.......slwaqkvKR.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.60|      17|      42|     561|     578|       4
---------------------------------------------------------------------------
  561-  578 (29.49/23.63)	PICEVFGScVPNVSWTLT
  606-  622 (32.11/19.41)	PLEHVVGD.VPPVGSQLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.40|      28|     161|     921|     957|       5
---------------------------------------------------------------------------
   11-   45 (43.54/21.37)	DSVVELTK.C.AQDKG..SDPLlwaiqlsSSLNSAGVYL
  924-  955 (35.86/36.25)	DAVVQLLKsCfTATLGlnSTPL.......SSNGGVGALL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.27|      36|     911|     214|     251|       7
---------------------------------------------------------------------------
  214-  251 (52.97/31.83)	FLEDSMDGsQVAVTSAIETLTVY.TGLVkSLQAVNGTTW
 1128- 1164 (65.30/32.16)	FLASVLDG.KVSLGCDWATWRAYvSGFV.SLMVGCTPTW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.66|      19|      42|     473|     493|      10
---------------------------------------------------------------------------
  473-  493 (26.84/19.44)	GSDDEKISAANILcgASLIRG
  518-  536 (34.82/17.88)	GSDSHLIGHAPML..NTLLVG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12729 with Med33 domain of Kingdom Viridiplantae
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