<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12727

Description mediator of RNA polymerase II transcription subunit 33A isoform X2
SequenceMAASVQTTLWDSVVELTKCAQDKGSDPLLWAIQLSSSLNSAGVYLPSTEVAHILVSHICWGNNVSIAWKFLERALAVKIAPPMLVLALLSCRALPSRRSRPTAYRLYMELLKRHAFSFASQINGPNWQKTMKSIDDVLHLSQIFGLQACEPGVLVVEFVFSIVWQLLDATLDDEGLLEMTPEKESKWSTRQQDMEIDGHDSFDEKRTEHQDRLRKANTVMAVELIGQFLQNKITSKLLYLARQNMPLHWGSFIQRLQLLGTNSMALKSSKISPEALVQFSSDTCKILSRECKTSTQQEFHAVMASRSMTSSAGKCFGASQSSLWLPLDLFLEDSMDGSQVAVTSAIETLTGLVKSLQAVNGTTWHDAFLGLWIAALRHVQRERDPIEGPVPRLDTRLCMLFSVTTLAIADIIEEEEAALIDETECSPNNQRKEKQVAGKRHKDLVSSLQILGDYEGLLTPPQSVVSVANQAAVKAMMFVSGVPVGSGYFECISMNDMPLNCSGNLRHLIVEACIARNLLDTSAYFWPGYVNRRINQIPHSMPAQVPGWSSLMKGAPLTSSMINALVSSPASSLAELEKIFDIAVNGSDDEKISAANILCGASLIRGWNIQEHTIHFVIRLLSPPVPADYSGSDSHLIGHAPMLNTLLVGIASVDCVQIFSLHGLVPQLAGALMPICEVFGSCVPNVSWTLTTGEEISAHAVFSNAFILLLRLWRFNHPPLEHVVGDVPPVGSQLTPEYLLLVRNSQLASSGINSKDRNKIRRQSTATNLSSVQPIFVDSFPKLKLWYRQHQACIASTLSGPVHGTPVHQIVDGLLNMVFRKMNKGSQSLTTGTSGSSTSSGPGNDDATLKPKLPAWDILEAVPFVIDAALTACSHGRLSPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPAFMNGTDWPSPAANLCNVEEQIKRILAATGVDVPSLAAGGTAPATLPLPLAAFVSFTITFKLDRASERSLNLAGPALESLSAGCPWPCMPIVASLWAQKVKRWSDFLIFSASRTVFHHNSDAVVQLLKSCFTATLGLNSTPLSSNGGVGALLGHGFGSHFYGGFSPVAPGILYLRVYRSIRDIMFMTEEILSLLMFSVREIVGDGLLRERMEKVKKTKNGMRYGQVSLAAAMTRVKLAALLGASFVWLSGGLGLVQSLIKETIPSWFISGHGSEQEGGCEGIVAMLRGYALAYFAVICGTFAWGVDSTTSASKRRAKILRAHMEFLASVLDGKVSLGCDWATWRAYVSGFVSLMVGCTPTWVLEVEVDVLKRLSKGLRQWNEEELALALLGRGGAGAMGAAAQLIVESEI
Length1326
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.07
Grand average of hydropathy0.133
Instability index44.71
Isoelectric point6.79
Molecular weight144165.77
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12727
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     894.07|     240|     245|     793|    1037|       1
---------------------------------------------------------------------------
  513-  748 (250.14/170.54)	.........................................CIArNLLDTSAYFWP........GYVN...RRINQIPHSMPAQVPGwSSLMKGAPLTSSMINALVssPASSLA....E.LEKIFDIAVNGSDDEKISAA.NILCG....................ASLIRG.WniqehtihfvirllsppvpadysgSDSHLIG...HAPMLNtlLVG..IASvDCVQ.IFSLHGL.VPQL.AGALMPICEVFgSCVPNVSWTLTTG..EE...ISAHavfsnafilllRLWRFNHPPLEHV........VGDVP....PVGSQLTPEYllLVRNSQLA
  752- 1023 (379.40/279.20)	INSKDRNKIRRQSTatnlssvqpifvdsfpklklwyrqhqaCIA.STLSGPVHGTPVHQI..VDGLLNMVFRKMNKGSQSLTTGTSG.SSTSSGPGNDDATLKPKL..PAWDIL....EAVPFVIDAALTACSHGRLSPR.ELATGLKDLADFLPASLATIVSYFSAEVTRGVW........................KPAFMNGtdWPSPAAN..LCN..VEE.QIKR.ILAATGVDVPSLAAGGTAPATLPL.PLAAFVSFTITFK..LD...RASE...........RSLNLAGPALESL........SAGCPWpcmPIVASLWAQK..VKRWSDFL
 1024- 1256 (264.53/180.03)	IFSASRTVFHHNSD...................avvqllksCFT.ATL.G.LNSTPLSSNggVGALLGHGF.....GSH.....FYG.GFSPVAPGI..LYLRVYR..SIRDIMfmteEILSLLMFSVREIVGDGLLRERmEKVKKTKNGMRYGQVSLAAAMTRVKLAALLGA...........................SFV....WLSGGLG..LVQslIKE.TIPSwFISGHGSEQEGGCEGIVA.MLRGY.ALAYFAVICGTFAwgVDsttSASK...........RRAKILRAHMEFLasvldgkvSLGCDW.......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     392.75|     128|     196|      34|     171|       2
---------------------------------------------------------------------------
   34-  171 (201.47/145.18)	LSSSLNSAGVYLPSTEVAhilvshICWGNNVSIAWKFLERALAV...KIAPPMLV.LALLSCRALpSRRSRPTAYRLYMELL.KRHAFSFASQINGPN....WQKTMKSIDDVLHLSQIFGLQACEP..GvLV..VEFVFSIVWQllDATL
  229-  369 (191.28/114.21)	LQNKITSKLLYLARQNMP......LHWGSFIQRLQLLGTNSMALkssKISPEALVqFSSDTCKIL.SRECKTSTQQEFHAVMaSRSMTSSAGKCFGASqsslWLPLDLFLEDSMDGSQVAVTSAIETltG.LVksLQAVNGTTWH..DAFL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12727 with Med33 domain of Kingdom Viridiplantae
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