<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12714

Description pre-mRNA-processing protein 40C
SequenceMSSSQELQSSASGITAQASGLGQATGPSNPTVASPAPVSGPSNPKGPSGTTNEPAQESIRAKFITGPGYVVPAPSFSYSVIPKQNTASGSSLENSSSPALVSNQPASATAFQPSIPGQSLSSGPTFSYNIIPPAKIGSSAQQKLQSSTDVGSGPLGHSQVGNSTPSTTAASLQPPVPGQPGHPNTFGPGTGAQFMASQGPSPVSVPKGAPSIATSFSFNRIPQLAQKDLSSNSSASVAVAREAGTVSPASSSSVPVSMPFHVSPSSLAAATSPNLCPATLWMPVAPSFVPPPGMPITPGTPGPPGIAPSTPLSSTVTVNSEAMDSSSSTSLRPVVPSTVQQQMHSPYPALPSMPPPPQGLWLPPQIGGLQRPPFLPYPGVLPGSYPLPMRGMPLPSVPVPDSQPPGISPLGPPGGTPSSSVGSVHLPSNTTGKQPDLPPPGTDQHKHIDDLADKVGATVNAKVDAWTAHKTETGVVYYYNALTGESTYERPSEFHGEPDKVTVQPTPVSCEKLVGTDWALVTTNDGKKYYYNSKTKISSWQVPMEVTELRRKYDDDALKGNMTLVQNSVAFSEKLSAPISVTAPAINTGGREATSLRPSGVAGSSSALDLIKKKLQDSIAPATSSPLPTSSGPTTADLNGSRPVEAAVKGLQSENKDKVKDINGDGNISDSSSDSEDEDSGPSKEECIIQFKEMLKERGVAPFSKWEKELPKIVFDPRFKAVPGYSARRALFEHYVRTRAEEERKEKRAAQKAAIEGFKQLLEEASEDIDQRTDYQTFKMKWGSDPRFEALDRKERELLLNERVLPLKKAAEEKAQAIRAAAASGFKSLLREKGDINTSSRWSRVKDSLRSDPRYKSVKHEDRELLFNEYISELKAADEEAEREAKVKREEEDKLKEREREMRKRKEREEQEMERVRLKVQRKEAVACYQALLVETIKDPQVSWTESRPRLEKDPQGRATNSVLDSGDAEKLFREHVKILYERCAREFRTLLCEVITTEAASQMTNDGKTVLTSWSTAKRLLKTDPRYSKMPRKEREALWRRHAEEILWKKKLVSDPKEEKLNIETKARSSLDSGRSPTGLRRSHSRR
Length1088
PositionUnknown
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.05
Grand average of hydropathy-0.644
Instability index61.66
Isoelectric point8.91
Molecular weight117451.51
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
RNA polymerase binding	GO:0070063	IBA:GO_Central
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12714
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     484.14|     105|     106|      95|     200|       1
---------------------------------------------------------------------------
    2-   67 (50.91/ 9.71)	.......................................................................SSSQELQSSA...SGI.......TAQaSGLG..QATgPSN....PTVAS.........PA..PVSG...PSNPK..GPsGT.TnepaqesirAKFIT..GP
   96-  199 (187.42/58.27)	SS...................PALVS...NQPASATAF.Q....PSIPGQSLSSGPTFSYN.IIPPAKIGSSAQQKLQSSTDVGSGP.......LGH.SQVG..NST.PST....TAASL.........QP..PVPG..QPGHPNTFGP.GT.G.........AQFMASQG.
  200-  311 (122.79/33.42)	.....................PSPVSvpkGAPSIATSF.SfnriPQLAQKDLSSNSSASVA.VAREAGTVSPAS...SSSVPV.SMPfhvspssLAA.ATSP..NLC.PATlwmpVAPSF.........VP..P......PGMPIT..P.GTpG.........PPGIAPSTP
  327-  461 (123.01/36.01)	SStslrpvvpstvqqqmhspyPALPS...MPPPPQGLWlP....PQIGG..LQRPPFLPYPgVLPGSYPLPMRGMPLPSVPVPDSQP.......PGI.SPLGppGGT.PSS....SVGSVhlpsnttgkQPdlPPPGtdQHKHIDDLAD.KV.G.........ATVNA....
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     428.75|      66|      66|     751|     816|       2
---------------------------------------------------------------------------
  688-  746 (75.55/38.96)	....IIQFKEMLKE....RGVAPFS.KWEKELPKIVF.......DPRFKA....VpGYSARRALF...EHYV.RT...RAEEERKE
  751-  816 (107.79/58.61)	QKAAIEGFKQLLEE..ASEDIDQRT.DYQTFKMKWGS.......DPRFEA....L.DRKERELLL...NERV.LPL.KKAAEEKAQ
  819-  882 (96.59/51.78)	RAAAASGFKSLLRE...KGDINTSS.RWSRVKDSLRS.......DPRYKS....V.KHEDRELLF...NEYI.SEL..KAADEEAE
  887-  925 (34.22/13.76)	VKREEE...DKLKE..REREMRK..................................RKEREEQE...MERVrLKVqRKEA.....
  926-  980 (51.47/24.27)	....VACYQALLVE..TIK..DPQV.SWTESRPRLEK.......DPQGRAtnsvL.DSGDAEKLF...REHV.KIL..........
  982- 1052 (63.13/31.38)	ERCARE.FRTLLCEviTTEAASQMTnDGKTVLTSWSTakrllktDPRYSK....M.PRKEREALWrrhAEEI.LWK.KK.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.38|      24|     262|     312|     337|       3
---------------------------------------------------------------------------
  312-  337 (36.74/20.21)	LSSTVTVNSEAMDSS..ssTSLRP..VVPS
  575-  604 (31.64/16.34)	LSAPISVTAPAINTGgreaTSLRPsgVAGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.87|      28|      49|     466|     493|       4
---------------------------------------------------------------------------
  466-  493 (51.85/31.00)	WTAHKTETGVVYYYNALTGESTYERPSE
  518-  545 (50.03/29.68)	WALVTTNDGKKYYYNSKTKISSWQVPME
  547-  568 (23.99/10.79)	.....TELRRKYDDDALKGNMTLVQNS.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12714 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEREAKVKREEEDKLKEREREMRKRKEREEQEMERV
2) GSSAQQKLQSSTDVGSGPLGHSQVGNSTPSTTAASLQPPVPGQPGHPNTFGPGTGAQFMASQGPSPVSVPKGA
3) IAPATSSPLPTSSGPTTADLNGSRPVEAAVKGLQSENKDKVKDINGDGNISDSSSDSEDEDSGPSKEECI
4) KDLSSNSSASVAVAREAGTVSPASSSSVPVSM
5) MSSSQELQSSASGITAQASGLGQATGPSNPTVASPAPVSGPSNPKGPSGTTNEPAQESIRAKFI
6) VIPKQNTASGSSLENSSSPALVSNQPASATAFQPSIPGQS
7) VPPPGMPITPGTPGPPGIAPSTPLSSTVTVNSEAMDSSSSTSLRPVVPSTVQQQMHSPYPALPSMPPPPQGLWLPPQIGG
8) YPLPMRGMPLPSVPVPDSQPPGISPLGPPGGTPSSSVGSVHLPSNTTGKQPDLPPPGTDQHKHIDDLADK
881
137
619
227
1
80
289
385
916
209
688
258
64
119
368
454










Molecular Recognition Features






MoRF SequenceStartStop




1) EILWKKKLVS
2) ESIRAKFITGPGY
3) FSFNRI
4) LIKKKL
5) TFSYNIIP
1046
57
216
610
125
1055
69
221
615
132