<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12704

Description mediator of RNA polymerase II transcription subunit 8
SequenceMAAMEGVIGAQAQDPSQVQQQQQQKVEKLNAAVQQQLNLESVKTRAIGLFKAISRILEDIDAIARTNSVPKWQDILGQFSMVNLELYNIVEDIKKVSKAFVVHPKNINAENATILPVMLSSKLLPEMEAEDNSKREQLLHGMQNLPIPTQIETLKKRIDMIGAACESAEKVIADTRKAYGLGTRQGPTIVPTLDKVQAAKIQEQESLLRAAVNYGEGLRIPGDQRHISSALPLHLVDVLTAGDGTQGFADASGMYQKNTPPLSSNTVGIQGAVPQGTGAQLIGRSVPSPSGTAGATSFDATSASPLSYANSPRSGANIMNTPSPQQQTQQQQQQQQQQQQQQQQQQRQKLISQLSPHQQQLLAQQQFRQSSASGLGQTQLPQLHDLPGQTQQKFQPVHGQHQMQFSQPLTHQSFQSRQLPGHVQHSIGQSQLNQGNQLRSHLSQFPGTANSALFNAAQPSPNSQMLSNMTNMSAAMPSQSHLPRMQFGLTGAHQRNPASQMMSDPMFNMGTTNPSMMPMQQQQQHGVQGGFGNIPANAQNLQPNMVALQNAAANPNFQQRQQGQQ
Length565
PositionHead
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.04
Grand average of hydropathy-0.613
Instability index58.65
Isoelectric point9.32
Molecular weight61540.49
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12704
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.90|      25|      32|      47|      71|       1
---------------------------------------------------------------------------
   47-   71 (41.45/35.63)	IGLFKAIS....RILEDIDAIARTNSV.PK
   76-  105 (32.46/26.31)	LGQFSMVNlelyNIVEDIKKVSKAFVVhPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.40|      18|      18|     415|     432|       4
---------------------------------------------------------------------------
  382-  403 (26.77/ 9.81)	QLHDLPGQTQQKFqpvhG..QHQM
  415-  432 (32.52/13.59)	QSRQLPGHVQHSI....G..QSQL
  434-  453 (23.10/ 7.40)	QGNQLRSHLSQFP....GtaNSAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.99|      28|      34|     456|     486|       5
---------------------------------------------------------------------------
  456-  478 (38.83/17.51)	.......................AAQPSPNSQMLSN.MTNMSAAMPS
  481-  515 (41.16/26.49)	HLPrMQ............fgltgAHQRNPASQMMSDpMFNMGTTNPS
  516-  555 (27.00/ 7.06)	MMP.MQqqqqhgvqggfgnipanAQNLQPNMVALQN.....AAANP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.73|      30|      36|     148|     182|       6
---------------------------------------------------------------------------
  148-  182 (41.65/48.09)	PTQIETLKKridmIGAA.CESAEKVIADTRKaYGLG
  187-  217 (46.08/34.27)	PTIVPTLDK....VQAAkIQEQESLLRAAVN.YGEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.50|      14|      34|     323|     336|       7
---------------------------------------------------------------------------
  323-  336 (27.96/ 9.81)	SP.QQQTQQQQQQQQ
  355-  369 (22.54/ 6.49)	SPhQQQLLAQQQFRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.61|      26|      41|     247|     272|       9
---------------------------------------------------------------------------
  232-  260 (34.69/14.76)	PL..HLVDVLTAgdgtqGF..ADASGMYQKNTP
  261-  287 (34.11/14.41)	PLSSNTVGIQGA..vpqG....TGAQLIGRSVP
  288-  312 (22.81/ 7.73)	..SPS..GTAGA....tSFdaTSASPLSYANSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12704 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QGFADASGMYQKNTPPLSSNTVGIQGAVPQGTGAQLIGRSVPSPSGTAGATSFDATSASPLSYANSPRSGANIMNTPSPQQQTQQQQQQQQQQQQQQQQQQRQKLISQLSPHQQQLLAQQQFRQSSASGLGQTQLPQLHDLPGQTQQKFQPVHGQHQMQFSQPLTHQSFQSRQLPGHVQHSIGQSQLNQGNQLRSHLSQFPGTANSALFNAAQPSPNSQMLSNMTNMSAAMPSQSHLPRMQFGLTGAHQRNPASQMMSDPMFNMGTTNPSMMPMQQQQQHGVQGGFGNIPANAQNLQPNMVALQNAAANPNFQQRQQGQQ
246
565










Molecular Recognition Features






MoRF SequenceStartStop




NANANA