<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12699

Description mediator of RNA polymerase II transcription subunit 16 isoform X1
SequenceMNSASVVKDSEEGAVSDTTVLEASRASDRAEAADNVEEEAVDKRDDPMEEDSASPPTVFRIRLKQPNSNLRHKMSVPELCRNFSSVSWCGKLNIIACASETCARIPSSNANPPFWIPIHIVNPERPTECAVFNVIADSPRDSVQFIEWSPASCPRALLIANFHGRITIWTQPSQGPVNLVRDGSCWQCEYEWRQDIAVVTKWLSGMSPYRWVSSNSSSSANSKSAFEEKFLSQQPQTSARWPNFLCVCSVFSSGSVQLHWSQWPPNQTGAASKWFSTSKGLLGAGPSGIMAADAIITEAGTMHVAGVPIVNPSTVVVWEVTPGPGNGIQATPKTTTTNGVPPSVNPPSWAGFAPLAAYLFSWQEYLGSEGTLKDTVSLHCSPVSNFSAYVSPEAASQSSATTTWGSGVTAVAFDPTRGGSVITVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQAVVLHPIFGNPTSSFGGQAPMQTVWLTRVNKSIPPTSDFKSPSAGQSGPTPNERSTPDSSVDKGNRVYFDPFDLPSDIRTLARIVYSAHGGEVAVAFLRGGVHIFSGASFTEVDNYIVNVGSAIATPAFSSTSCCLATVWHDNNKDRTILKIIRVLPPAVPSSQVKVNAATWERAIADRFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSTQHRQQHGPSLDRIKCRLLEGTNAQEVRALVLDMQARLLLDMLGKGIESALINPANLVSEPWQASGEMLSGIDPDAMTVEPALVSSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVGATSSTGSNRNMVTSPTHSSASSVTSQGGQSGTSSTGNSQMQAWMQGAIAKISSSSDGVSYSTPNPMSGPAPFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRKQMPRYIGGAQRNTDSNMQKPQPVAPGKVEEVNSVPARPAPGMTRSEDVQGARTGQPVSGAKGVEEGPVSRSVRVGSGNAGQGYTFDEVKVLFLILMDLCRRTAGLAHPLPVSQVGGSNIQIRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPEGAIDDNSKLSNSFGPFEFNSSEDYNSYYGDLGLWPRKRRMSERDAAFGLKTSVGLGAYFGIMGSRRDVVTAVWKTGLEGVWYKCIRCLRQTSAFASPGSASPNQNDREAWWISRWCYGCPMCGGTWVRVV
Length1231
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy-0.216
Instability index46.87
Isoelectric point6.19
Molecular weight133090.27
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12699
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     192.46|      63|      92|     431|     499|       1
---------------------------------------------------------------------------
  431-  499 (93.03/72.55)	YMSPYD.PDEGPSITgwRVqRWESSLQAVVLHPIFGNpTSSFGGqAPMQTV..WLTRVNKSIpPTSDFKSPS
  524-  589 (99.43/53.58)	YFDPFDlPSDIRTLA..RI.VYSAHGGEVAVAFLRGG.VHIFSG.ASFTEVdnYIVNVGSAI.ATPAFSSTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.52|      13|     937|     232|     267|       4
---------------------------------------------------------------------------
  248-  267 (20.60/17.56)	C....SVFSS.GSVQlhwsqwpPNQ
 1188- 1205 (16.92/20.06)	ClrqtSAFASpGSAS.......PNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.49|      20|     354|     501|     520|       5
---------------------------------------------------------------------------
  501-  520 (38.45/19.27)	GQSGPTPNERSTPDS....SVDKG
  858-  881 (34.04/16.18)	GVSYSTPNPMSGPAPfmpiSINTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.90|      13|     115|     780|     792|       8
---------------------------------------------------------------------------
  780-  792 (26.05/19.00)	HFITRLRRYASFC
  896-  908 (26.85/19.81)	HFLHRLCQLLLFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.64|      13|      15|     943|     955|      13
---------------------------------------------------------------------------
  943-  955 (23.23/13.13)	EEVNSV.PARPAPG
  960-  973 (18.40/ 8.61)	EDVQGArTGQPVSG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12699 with Med16 domain of Kingdom Viridiplantae
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