<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12693

Description mediator of RNA polymerase II transcription subunit 15a-like
SequenceMNLTSDIKIQQQQREQLDVTWFLVGLKIEYEPVKAQILGGSALPALEEVFARLRRISLSPIESNITFDRSALVSTRGGSYGHKGGGRTIKGGRSNPMGGRSSEGGVIQGEAVAEEGGAQQGSAHIVGEKDTQFTFVMIYMSHHPQVPLPLLVDNSIPVVPIMPESPPSPLQERTERPPIHQVYTDRQKPAPPPPSTSEADLAPSTIEFAFDLDLPIVLRKAGKILLVVYVDDIVIIGSDRVGIDRLKTFLQDHFQTKDLGKLKYFLGIEVATSKQGINLCQRKYEEVFMDPPLGYDMKSKVFKLKRALYGLKQLPWEWFERLCKAMKVVGYTQDSAENTLFYRKKGKKLTASIVYVDMAQSIKEIYLPDIKVLYQKITANLQKQDSLTQPPKSEQNSKLKTLKIMLDSFIHFLHLPKSNIGPSDKEKLDNFDRNIIGLLNSMRAKKHVSGNQQGQQQLRPPCAQSHTMQQQQQQLQSQIHLMPPHEKRMNTQMQPMNLQSSVTSIKPAAVTSMRHGSIPQSTSLGFPTAQPNMTSSLQNLESGQGNARSSLQQRVIGSLQHNTMITTQQENINSASQGPLMLRPKIYSYQPSSYMLQNQQLRQQQEQQVIQTQQLKQQCQQRQVHQQLFQQQKPQNLQQQLHQQKQQQPVGNHMSLHHINDADDMNMKQGMSVKSGTFQKPYMAGQHSVYHNQQRKPNASIPIASPQLLQATSPQISQHFSPQIDQQNLHSLSRSGTPLHSANSPFVVASPSTPLAPSPIPGDLEKQSPSVCLLSNTGNTGQPQTDITPSQGQSQLLSIATPGISPSPLLAEFTGPDIDLGTTSTISSEKSGATDRPLERLIKVVRSISSKALGASMGEIKSVVNIDRITGSEPSKESIHSINEDLVAMQKLHLQRRKFFSQDVIFQCLDTLVVEAFGCSNDDQPLSHVKKIDSVDQVMEDKRYATNKMKRQTSSMPLNDVSSSITDDDFEQSHSLEVCEFNSTATSRIKRPRIEANHALLKEIREINQQLISTVVEEDTIPIIGSDTDESGEGTIVKCSFSTVALKVDFIPDYPSSLMSPILPLRLLVPTNYPDSSPIPLDKLPGELSKEYEDLSAKAKSRFSLSLRNLSQPLSLREMAKTWDLCSHMVLAEYAQQNGGGTFSSKYSTWENCMGAA
Length1157
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.05
Grand average of hydropathy-0.503
Instability index57.72
Isoelectric point8.62
Molecular weight128690.95
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IBA:GO_Central
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12693
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.72|      15|      15|     613|     627|       1
---------------------------------------------------------------------------
  452-  468 (23.48/ 8.30)	QQgqQQLRPPCAQSHTM
  469-  480 (22.85/ 7.87)	QQ..QQQQ...LQSQIH
  626-  642 (25.40/ 9.62)	QQlfQQQKPQNLQQQLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.54|      15|      15|     737|     751|       2
---------------------------------------------------------------------------
  737-  751 (27.95/14.13)	TP......LHSANSP..FVVASP
  753-  769 (23.30/10.47)	TP......LAPSPIPgdLEKQSP
  788-  806 (18.29/ 6.54)	TPsqgqsqLLSIATP..GI..SP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.29|      28|      33|     515|     545|       3
---------------------------------------------------------------------------
  515-  545 (40.20/29.95)	HGSIPQSTsLGfpTAQPN..MTSSLQNLES.GQG
  548-  578 (37.09/17.37)	RSSLQQRV.IG..SLQHNtmITTQQENINSaSQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.09|      13|      16|    1050|    1065|       4
---------------------------------------------------------------------------
 1050- 1065 (19.39/17.93)	FIP.DYPSSlmSPIlPL
 1068- 1081 (23.70/10.41)	LVPtNYPDS..SPI.PL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.57|      15|      16|     693|     708|       6
---------------------------------------------------------------------------
  693-  708 (23.66/16.55)	QQRKPNASIPIaSPQL
  710-  724 (27.91/15.17)	QATSPQISQHF.SPQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.03|      19|      19|     826|     844|       7
---------------------------------------------------------------------------
  826-  844 (30.45/18.96)	ISSEKSGATDRPLERLIKV
  848-  866 (28.58/17.32)	ISSKALGASMGEIKSVVNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.57|      15|      17|     952|     966|       9
---------------------------------------------------------------------------
  952-  966 (24.77/14.67)	QTSSMPLNDVSSSIT
  972-  986 (25.80/15.58)	QSHSLEVCEFNSTAT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12693 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IMPESPPSPLQERTERPPIHQVYTDRQKPAPPPPSTSEAD
2) MRAKKHVSGNQQGQQQLRPPCAQSHTMQQQQQQLQSQIHLMPPHEKRMNTQMQPMNLQSSVTSIKPAAVTSMRHGSIPQSTSLGFPTAQPNMTSSLQNLESGQGNARSSLQQRVIGSLQHNTMITTQQENINSASQGPLMLRP
3) QRQVHQQLFQQQKPQNLQQQLHQQKQQQPVGNHMSLHHINDADDMNMKQGMSVKSGTFQKPYMAGQHSVYHNQQRKPNASIPIASPQLLQATSPQISQHFSPQIDQQNLHSLSRSGTPLHSANSPFVVASPSTPLAPSPIPGDLEKQSPSVCLLSNTGNTGQPQTDITPSQGQSQLLSIAT
4) RGGSYGHKGGGRTIKGGRSNPMGGRSSEGGVIQGEAVAEEGGAQQGSAHI
161
442
621
76
200
584
801
125










Molecular Recognition Features






MoRF SequenceStartStop




NANANA