<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12689

Description mediator of RNA polymerase II transcription subunit 16 isoform X2
SequenceMNSASVVKDSEEGAVSDTTVLEASRASDRAEAADNVEEEAVDKRDDPMEEDSASPPTVFRIRLKQPNSNLRHKMSVPELCRNFSSVSWCGKLNIIACASETCARIPSSNANPPFWIPIHIVNPERPTECAVFNVIADSPRDSVQFIEWSPASCPRALLIANFHGRITIWTQPSQGPVNLVRDGSCWQCEYEWRQDIAVVTKWLSGMSPYRWVSSNSSSSANSKSAFEEKFLSQQPQTSARWPNFLCVCSVFSSGSVQLHWSQWPPNQTGAASKWFSTSKGLLGAGPSGIMAADAIITEAGTMHVAGVPIVNPSTVVVWEVTPGPGNGIQATPKTTTTNGVPPSVNPPSWAGFAPLAAYLFSWQEYLGSEGTLKDTVSLHCSPVSNFSAYVSPEAASQSSATTTWGSGVTAVAFDPTRGGSVITVVIVEVSLNSVIAVLDADFHSLPSTQHRQQHGPSLDRIKCRLLEGTNAQEVRALVLDMQARLLLDMLGKGIESALINPANLVSEPWQASGEMLSGIDPDAMTVEPALVSSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVGATSSTGSNRNMVTSPTHSSASSVTSQGGQSGTSSTGNSQMQAWMQGAIAKISSSSDGVSYSTPNPMSGPAPFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRKQMPRYIGGAQRNTDSNMQKPQPVAPGKVEEVNSVPARPAPGMTRSEDVQGARTGQPVSGAKGVEEGPVSRSVRVGSGNAGQGYTFDEVKVLFLILMDLCRRTAGLAHPLPVSQVGGSNIQIRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPEGAIDDNSKLSNSFGPFEFNSSEDYNSYYGDLGLWPRKRRMSERDAAFGLKTSVGLGAYFGIMGSRRDVVTAVWKTGLEGVWYKCIRCLRQTSAFASPGSASPNQNDREAWWISRWCYGCPMCGGTWVRVV
Length998
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy-0.225
Instability index47.14
Isoelectric point6.37
Molecular weight107807.28
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12689
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.14|      21|      24|     488|     511|       1
---------------------------------------------------------------------------
  488-  511 (27.14/36.75)	DMLgKGIES.AL.INPAnLVSePWQA
  514-  536 (30.00/20.61)	EML.SGIDPdAMtVEPA.LVS.SIQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.98|      13|      20|     230|     242|       3
---------------------------------------------------------------------------
  230-  242 (25.28/13.88)	FLSQQPQ.TSARWP
  251-  264 (22.70/11.59)	FSSGSVQlHWSQWP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.71|      10|      20|     148|     157|       5
---------------------------------------------------------------------------
  148-  157 (21.21/10.36)	WS.PASCPRAL
  169-  179 (16.50/ 6.24)	WTqPSQGPVNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.74|      15|      24|     721|     736|       6
---------------------------------------------------------------------------
  721-  736 (23.21/18.47)	PgMTRSEDVQGARTGQ
  748-  762 (26.53/15.58)	P.VSRSVRVGSGNAGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.85|      30|     354|     543|     581|       7
---------------------------------------------------------------------------
  547-  576 (53.81/50.59)	HFITRLRRYASFC.....RTLASHAVGATSSTGSN
  663-  697 (52.04/26.01)	HFLHRLCQLLLFCfffrrKQMPRYIGGAQRNTDSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.10|      55|     572|     362|     425|       9
---------------------------------------------------------------------------
  362-  425 (78.36/55.15)	WQeyLGSEGTLKDTVslHCspVSNFSAYVSPEAAS..QSSATTTWgsgVTAVAFD.PTRGGSVITVV
  941-  998 (102.74/48.23)	WK..TGLEGVWYKCI..RC..LRQTSAFASPGSASpnQNDREAWW...ISRWCYGcPMCGGTWVRVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.61|      24|      25|     304|     327|      10
---------------------------------------------------------------------------
  284-  304 (24.59/10.98)	AG.....PSGIMAADaiITEAGTMHV
  305-  328 (41.93/24.96)	AGVPIVNPSTVVVWE..VTPGPGNGI
  329-  351 (34.09/18.64)	QATPKTTTTNGVPPS..VNPPSWAG.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.19|      28|     523|     108|     137|      11
---------------------------------------------------------------------------
  108-  137 (45.72/32.67)	SNANP.....PFwIPIHIVNPERPTECAVfNVIAD
  629-  661 (49.46/25.36)	STPNPmsgpaPF.MPISINTGTFPGTPAV.RLIGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.06|      25|      30|     876|     900|      14
---------------------------------------------------------------------------
  876-  900 (45.60/30.97)	KLSNSFGPFEFNSSEDYNSYYGDLG
  907-  931 (43.46/29.16)	RMSERDAAFGLKTSVGLGAYFGIMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.57|      18|      19|     448|     466|      15
---------------------------------------------------------------------------
  448-  466 (28.94/23.50)	TQHRQQHGPSLDrIKCRLL
  469-  486 (28.63/17.83)	TNAQEVRALVLD.MQARLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12689 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IGGAQRNTDSNMQKPQPVAPGKVEEVNSVPARPAPGMTRSEDVQGARTGQPVSGAKGVEEGPVSRSVRVGS
2) MNSASVVKDSEEGAVSDTTVLEASRASDRAEAADNVEEEAVDKRDDPMEEDSASPPTVFRI
3) TSSTGSNRNMVTSPTHSSASSVTSQGGQSGTSSTGNSQ
687
1
570
757
61
607










Molecular Recognition Features






MoRF SequenceStartStop




1) AADNVEEE
2) VFRIRLKQ
32
58
39
65