<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12682

Description U-box domain-containing protein 33-like isoform X1
SequenceMESGGEITEALPSTSNVQDKIFVAVGKDVKESKSTLLWALRNSGRDKICILHVHQPPRTIPLMGGNLPISAASEKEARLHQDHERQKMHDTLNEYLSICLSTGVQAEKLDIEMDSIEQGIVELIAQHGNKKLVMGAAADKHYSKRMMDLKSKKAIYVSKQAHSSCHIWFICRGNLIYTREGSSKGSETEVFPTPMASPSTRPTQSASFNSGSLLQAQNSHVRLTNPVQDLLFRLVKSDKFVSHRGRLTASSSSEVSGEMAIPRIQSSIEVTANGWEMISRSFPSQSSGNSTWSSIGEAGNLDTTSMTTNAQSDEGLSSLYEPNEDLHCTSPANDPVLVEQGPVNDELYDQLLQAMADAENSKQEAFEESVRRRKAERDAIEAIRRAKASEMSYEKEKLQRKEMEELLAKEKRKVEKMKSLLEQATEELQIAQGKKSVLERQICYTNSELLELEEKLVLADELILNLKNERDELEKERESAVGEALELRKKMEDDDTSISRMQCFSEFSAEEIKEATQNFDPALKIGEGGCGSVYRGHLRHTQVAIKMLHSHSSQGLIEFQREVDVLSRVRHQNLVTLIGTCPEMWCLIYEYLPNGSLEDRLACKDNTPPLSWQMRTRIAAEMCSALMFLHSHTPHRIVHGDLKPANILLDANFVSKLGDFGICRFIPHDEDSACWRTDPKGTFAYADPEFLSTGELTPKSDVYSFGVVLLRLLTGRPPLGIMREMQYALEKDNLDAVLDASAGNWPFVQARQLAHLALRCCEISRKNRPELRSDPWRVLEPMKASCAVSSSAHLGPVDYGRVPSYFICPVFQEIMRDPHIAADGYTYEAEALKAWIDSGHDTSPMTNLKLAHCNLIPNHALRSAIQEWLQNHP
Length873
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.06
Grand average of hydropathy-0.465
Instability index44.05
Isoelectric point5.74
Molecular weight97834.86
Publications
PubMed=23663246

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12682
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.23|      27|      90|     374|     405|       1
---------------------------------------------------------------------------
  362-  394 (36.07/27.24)	KQEAFEesvrrrKAERDAIEAIRRAKA.SEMSYE
  467-  486 (23.30/ 9.43)	............KNERDELEKERESAV.GE.ALE
  487-  510 (33.86/14.91)	LRKKME..........DDDTSISRMQCfSEFSAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     185.13|      60|     364|     397|     460|       3
---------------------------------------------------------------------------
  397-  460 (85.32/71.23)	KLQRKEMEELLAKEKRKVEKMK.SLLEQATEEL.QIAQGKksVLERQICYTNSELleLEEKLVLAD
  762-  823 (99.81/70.08)	EISRKNRPELRSDPWRVLEPMKaSCAVSSSAHLgPVDYGR..VPSYFICPVFQEI..MRDPHIAAD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12682 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SSGNSTWSSIGEAGNLDTTSMTTNAQSDEGLSSLYEPNEDLHCTSPANDPVLVEQGPV
286
343










Molecular Recognition Features






MoRF SequenceStartStop




NANANA