<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12676

Description mediator of RNA polymerase II transcription subunit 16-like
SequenceMDALTHHIQGEVPWCTLFADDIVLIDETQGGVYERSEIWRQTLESKGFKLSRTKTEYIECKFSSISGEADMDVRLESQVVTKKESFKYLGLVIQEDGEIDEDVTHRIGVGWMKCRLASGVLSDKKIYCLLFLTCLFDCFLSAVAWCGKLNAIACASETCARIPSSNANPPFWIPVHIVIPERPTECTVFNVIADSPRDSVQFIEWSPTSCPRALLIANFHGRITIWTQTSQGPANLVRDASCWQREYEWRQDIAVVTKWLSGVSPYRWLSTRTGGSAKSTFEEKFLSQQPQSPAGWPNFLCVCSVFSSGSVQLHWSQWPPNQNGTPSKWFCTSKGLLGAGPSGIMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGPGNGFQAIPKTSVSNGVPPSLNPPSWDGFAPLAAYLFSWQECLLQEAKQGKKLTEQHYNDMVALHCSPVSNFSAYVSPEAAAQSTATTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSVEDVVLHQIFGNPTSSFGGQAPKQTVWVSKVIKCIPAGNDFNRPLAVGAGPVSDGRNMADSGMEMGKRVSFDPFDLPSDVRTLARIVYSAHGGEIAVAFLRGGVHVFSGPSFTPVDNYHIDVGSAISAPAFSSTSCCSASVWHDTSRDCTILKIIRVLPPAVPSNQGKANSANWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVALNSVIAVLDADFHSLPSTQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALTNPSALVPEPWQASSETLFGIDPEAMAVEPALVPSIQAYVDAILDLASHFITRLRRYASFCRTLASHAVTAGTGGSRSMVTSPTPSVTSPATSQGAQGGTASSTGNTQMQAWVQGAIAKISSTADSVPSSAPNPITGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLHFCFFFRGTQLPRFMGAAQRNADSSMQKPQPSIPGKAEDSNSGAKPTPGGQVGTGAKGSEEGPSKRSRIGSGNAGQGYTYEEVRVLFLILMDLCRRTAGLVHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDSEDIGGVDDNSKLSPSRDLTECSSSENCDVSYGAHGLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTAVWKTGLEGVWYKCIRCLRQTSAFTSPGGNPSATQNEKEVWWISRWAYGCPMCGGTWVRVV
Length1283
PositionTail
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.09
Grand average of hydropathy-0.145
Instability index45.63
Isoelectric point6.07
Molecular weight138938.71
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12676
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.22|      42|     122|     866|     910|       1
---------------------------------------------------------------------------
  866-  910 (64.86/38.28)	AGTGGSRSMVTSPTPSVtsPATSQGAQGGTASSTGNtQMQAWVQG
  985- 1026 (73.36/34.98)	AAQRNADSSMQKPQPSI..PGKAEDSNSGAKPTPGG.QVGTGAKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.64|      13|     112|     835|     856|       2
---------------------------------------------------------------------------
  844-  856 (26.22/26.06)	HFITRLRRYASFC
  959-  971 (27.42/ 8.99)	HFLHRLCQLLHFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     494.22|     144|     184|     378|     521|       4
---------------------------------------------------------------------------
  170-  401 (153.65/73.20)	PFWipvhiviperptectvfnviadsprDSVQ......FiEWSptSCpraLLIANFHGRiTIWTQTSQGP.ANL....VRDASCWQREYEWRQDIAVvTKWLSGVSPYRW............LSTRtGGS..AKSTFEEKFLSqqpqspagwpnflcvcsvfssgsvqlhwsQWPPNQNGTPSK......W........FCTSkgllgagpsgimaadaiITD......................sgamhvagvpivnpstvvvwevtpGPGNGFQAIPKTSVSNGVPPSLNP
  402-  591 (236.68/116.75)	PSW.........................DGFAPLAAYLF.SWQ..EC...LLQEAKQGK.KLTEQHYNDM.VALHCSPVSNFSAYVSPEAAAQSTAT.TTWGSGVTAVAF............DPTR.GGSVIAVVIVEGQYMS.............................PYDPDEGPSITG......WR...VQR.WESS.................VEDvvlhqifgnptssfggqapkqtvwvskvikcipagndfnrplavgaGPVSDGRNMADSGMEMGKRVSFDP
  595-  703 (103.90/47.11)	PS..........................D.VRTLARIVY.S.......................AHGGEIaVAFLRGGVHVFS...GPSFTPVDNYH.IDVGSAISAPAFsstsccsasvwhDTSR.DCTILKIIRV....LP.............................P....AVPSNQGkansanWEraiAERfWWS...........................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.88|      40|     762|     151|     194|       5
---------------------------------------------------------------------------
  151-  194 (64.49/40.97)	AIACASETCARIPSSNANP....pfwIPVHIVIPERPTECTVfNVIAD
  911-  957 (65.38/36.97)	AIAKISSTADSVPSSAPNPitgpstfMPISINTGTFPGTPAV.RLIGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.75|      14|     337|     805|     819|       6
---------------------------------------------------------------------------
  805-  819 (23.54/17.77)	PWqASSETLFGIDPE
 1145- 1158 (28.21/16.42)	PW.SDSEDIGGVDDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.77|      17|      18|     745|     762|      11
---------------------------------------------------------------------------
  745-  762 (27.05/23.56)	TQHRQQYGPSLDrIKCRL
  766-  782 (27.72/18.31)	TNAQEVRAMVLD.MQARL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12676 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GAAQRNADSSMQKPQPSIPGKAEDSNSGAKPTPGGQVGTGAKGSEEGPSKRSRIGSGN
2) GTGGSRSMVTSPTPSVTSPATSQGAQGGTASSTGNT
984
867
1041
902










Molecular Recognition Features






MoRF SequenceStartStop




NANANA