<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12658

Description mediator of RNA polymerase II transcription subunit 34 isoform X3
SequenceMGRTEELFEELMNVEVELHDVQDQIKLLLDRQEKLHERQSELKALLESCESSSGPGDDNAAVSVDDWSRPFVWDSQADDIRFNVFGISKYRANQREIINAIMSGRDVLVIMAAGGGKSLCYQLPAVLRDGVALVVSPLLSLIQDQVMGLAALGIPAFMLTSTTSKENEKFIYKALEKGDDELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYKNLGILKTQFPNVPVVALTATATKKVQDDLMEMLHIPRCVKFVSSVNRPNLYYMVREKSSVGKTVVDEIAEYIRTSYPNNESGIVYCFSRKECEQVAQELRERGISTDHYHADMDVNAREKVHLRWSSGKLQVIVGTVAFGMGINKPDVRFVVHHSLSKSMETYYQESGRAGRDGLPSECVLFFRPADVPRQSSMVFYENSGLKNLYDIVRYCQVWLLNSSL
Length455
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.08
Grand average of hydropathy-0.270
Instability index39.79
Isoelectric point6.10
Molecular weight51480.34
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
helicase activity	GO:0004386	IEA:InterPro
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12658
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.27|      15|      15|      19|      33|       1
---------------------------------------------------------------------------
   19-   33 (25.63/21.48)	HDVQDQIKLLLDRQE
   36-   50 (25.64/21.49)	HERQSELKALLESCE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.13|      48|     195|     174|     231|       2
---------------------------------------------------------------------------
  174-  231 (66.61/85.80)	ALEKGDDELKILYVTPEKISKSkrFMSKLEKCHHAGRLSLISidEahcCSQWghdFRP
  372-  419 (88.53/69.16)	AFGMGINKPDVRFVVHHSLSKS..METYYQESGRAGRDGLPS..E...CVLF...FRP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12658 with Med34 domain of Kingdom Viridiplantae
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