<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12653

Description heat shock 70 kDa protein
SequenceMAKAEGKAIGIDLGTTYSCVGVWQNDRVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRRFSDPTVQSDMKHWPFKVVSGPGDKPMIVVQYKGEEKQFAPEEISSMVLTKMKEVAEAFLGQTVKNAVVTVPAYFNDSQRQATKDAGAISGLNVMRIINEPTAAAIAYGLDKKASRSGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVQDFKRKHKKDISGNARALRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYATITRARFEEMNMDLFRKCMEPVEKCLRDAKIDKSHVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQATILSGEGDQKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERPMTKDNNLLGKFELKGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNKITITNDKGRLSKEEIERLVQEAERYKAEDESMKKKVEAKNALENYAYNMRNTVRDEKFSGKLDPSDKQKIEKAVDETIDWLDGNQLAEVDEFEDKLKDLENLCNPIIAKMYQGGAGGDVPMGGSADTGAGYGKAGSTNNGAGPKIEEVD
Length654
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.455
Instability index29.89
Isoelectric point5.34
Molecular weight71827.52
Publications
PubMed=23773524

Function

Annotated function Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. 
GO - Cellular Component
endoplasmic reticulum lumen	GO:0005788	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12653
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     349.71|     119|     287|     199|     322|       4
---------------------------------------------------------------------------
  199-  322 (182.88/128.20)	NVlIFDL.GGGTFDVSLLTIEEGI.FEVKATAGDTHLGGEDFDnRLVN....HFVQD..FKRK..HKKDISGNARALR.RLRTacERAKRTLSSTAQTTIE..IDSLYEGIDFYATITRARFEEMNMDLFRKCmEPV
  480-  611 (166.82/99.75)	NV.CFDIdANGILNVSAEDKTAGVkNKITITNDKGRLSKEEIE.RLVQeaerYKAEDesMKKKveAKNALENYAYNMRnTVRD..EKFSGKLDPSDKQKIEkaVDETIDWLDGNQLAEVDEFEDKLKDLENLC.NPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.00|      18|      21|      37|      54|       5
---------------------------------------------------------------------------
   15-   32 (19.59/11.59)	....TTYSCVGVWQNDRveIIP
   37-   54 (32.67/24.42)	NR..TTPSYVAFTDTER..LIG
   59-   77 (24.74/16.64)	NQvaMNPQNTVF.DAKR..LIG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12653 with Med37 domain of Kingdom Viridiplantae
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