<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12648

Description mediator of RNA polymerase II transcription subunit 33A-like
SequenceMKMETVHSIFDRVTELTKLAQEKNTDPLIWAMQLSSSLNSAGVSMPSVAVGEILVNHICWSNNVPIAWKFLEKALTVRIVPPLFVLALLSTRVIPTRRSCPMAYRLYMELLKRYASSLPSLSNGPNYQKIMESINDTLHLSQIFELQGSESGKHVVGYVFMVVWQLLDASLDDEGLLELTAEKKSRWPVATQEMEISNRDGFVGKRVEHREGLCRMNTVLAIEIIGELFGDKLTSMILYLARKNMPTHWDSFMQHLQLLVSNSAALRNSKDISPEALVLLISKNLGVLSRECNTSSRQFFHAVMASGSLAFSASRRDAASTSVLWLPIDLFLEDTMDGLQVAATSSADTLTGLVKALQATNRTTWQDTFFGLWISALRLVNRERDSSEGPVPRLDTCLCLLLSITPLAITNIIEEENDSTSSDQRKESTGKRCQALVSSLQQLHDYEGLLTPPLPAIPLANQAAVKAMMFLSGLSMGSEYFDGMKLNGMPVNCAGNLWHLIVEACIARNILDTSAYLWPGYVKGQCNQVPRSISGPLLGWSSLMKGSLLTPPMVSALVSAPASSLAEIEKIYEIAVDGSDEEKISAATILCGASLARGWNIQEHTVLFITRLLSPCVPSDYCGTESHLISYAPVLNVLLIGISSIDCIQIFSLHGLVPQLAGALMPICEAFGSCAPNISWTLMSEKINSHAVFSNAFTLLLKLWRFDQPPLEHVTRDVPVGSHLTPEYLLLVRNSQLACSEDLLKGQSKSKQLSRTPCRLPEEPIFMDSFPKLKCWYRQNQACIASPLSGLVPGTPVHQIVEALLNFMFRKINSAGQSLTPTTSGSSNSSGSGNEDISPHLKLPAWDVLEAVPFVLDAALTACAHGRLSPRELATGLKDLADFLPASLATIASYFSAEVTRGLWKPAFMNGTDWPSPAANLATVEQQIKKILAATGVDVPSVSVGGNSPAIIPLPLAVLVSLTITYKLERGTDRFLNLVGTALSNLATSCPWPCMPVIAALWMQKVRRWSDFLVFSASRTVFHHSSDAVVQLLRVCFTATLGLGTSSIESNGGVGSLLGHGFGSHFSGGISPVAPGILYLRVHRVVRNVMFMAEEVVTLLMHFVRIIADGGFPAEELEKLKKTRNPMSSLSCHNMESGFPAFCQVSLAAAMTRVKLAASLGASLVWITGGLSLVQALLKETLPSWFISAHRSEPNGGVSEGMVARLRGYVLAYFALLSGTFAWGVDSLSPASKWRPSILGAHLEFLASALDGKITLGCNKATWRAYVSGFIGLMVGCTPKWLLEVDVEVLKRLSKGLKRLNEEVLALALLETSGVGAMGTAAEMIIEGGLNFC
Length1333
PositionTail
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy0.206
Instability index44.56
Isoelectric point6.65
Molecular weight144866.44
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12648
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.85|      45|      93|    1183|    1233|       1
---------------------------------------------------------------------------
 1183- 1233 (61.32/52.91)	PSWFISAHrSEPNGGVSEGMvARLRGYVLAyFALLSGTfawGVDSLSPASK
 1279- 1323 (71.53/38.82)	PKWLLEVD.VEVLKRLSKGL.KRLNEEVLA.LALLETS...GVGAMGTAAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     901.70|     291|     516|      27|     377|       2
---------------------------------------------------------------------------
   27-  346 (456.62/336.86)	PLI.WA..MQ...LSSSLNSAGVSMPSVAVGE....I.LVNHIC..WSNNVPI.AWKFLEKALTVRIVP.....PLFVLALLSTRVIPTRRSC.PMAYRLYMELLKRYASSLPSLSNGpnyqkiMESInDTLhlsQIFELQG...SESGKHV.VGYVF.....MVVWQLLDASLDDEG........LLELtaekksrWPVATQEMEISNRDGFVGKRVEHREGLCRMNTVLAIE...IIGELFGDKLTSMILYLARKnmPTHWDSFMQHLQLLVSNSAALRNS.KDISP........EALvllisknLGVLSRECNTSSRQFFHAvmASGSLAFSASRRDAASTSvLWLPIDLFLEDTMDGLQVAATSS
  536-  863 (414.37/247.89)	PLLgWSslMKgslLTPPMVSALVSAPASSLAE....IeKIYEIAvdGSDEEKIsAATILCGASLARGWNiqehtVLFITRLLS........PCvPSDYCGTESHLISYAPVLNVLLIG......ISSI.DCI...QIFSLHGlvpQLAGALMpICEAFgscapNISWTLMSEKINSHAvfsnaftlLLKL.......WRFDQPPLEHVTRDVPVGSHLTPEYLLLVRNSQLACSedlLKGQSKSKQLSRTPCRLPEE..PIFMDSFPKLKCWYRQNQACIASPlSGLVPgtpvhqivEAL.......LNFMFRKINSAGQSLTPT..TSGSSNSSGSGNEDISPH.LKLPAWDVLEAVPFVLDAALTAC
  928- 1013 (30.71/29.72)	.............IKKILAATGVDVPSVSVGGnspaI.IPLPLA..VLVSLTI.TYK.LERG.TDRFLN.......LVGTALSNLATSCPWPCmPVIAALWMQKVRRWSDFL.................................................................................................................................................................................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.83|      29|      33|     379|     407|       5
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  379-  407 (49.75/31.06)	LVNRERDSSEGPVPRLDT...CLCLLLSITPL
  412-  443 (39.08/22.72)	IIEEENDSTSSDQRKESTgkrCQALVSSLQQL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12648 with Med33 domain of Kingdom Viridiplantae
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