<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12636

Description ATP-dependent DNA helicase Q-like 4A isoform X2
SequenceMTVNSAGGSMSKDKLPKVNWTQHATAHENFSCQDKFLTSNFLFSLPTQKPCVREQMNARSMACQVRSVTKLETEKAWKLLNSLKLSSKSYTRPGKTLPLTKENKTFSQHSHNTHVPRASDVNYASARCTPLHQGVDENSEYSDTTRYAGNRFPSHSSGVAETGNVVNRQNGADTSVGNNSHSRGIVGISSNHAIGVSKTRESDSTYADGTEEDDILQNIDIDQIVEHYQTNCTPQPSVSRCPPITPVTDSKCLAGSGETNLPPELSLNCNHGLKLGLCPEALDHLQEMKDRLINISNDLLDNVSELSLEQVEMLRQERSQLKLQIQHLEKFLQTASGNEERRMSQFSASTQTSAFQYETPRAVPSRIDPIRLDTQFHGYNESGGFGNWNSSSLSFDVTGGYGLSTAPVEREPYIPKYLDVKYTEGSNDKKWSSRDFPWTKKLEADNKKVFGNPSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQVNIPAAYLSSNMEWTEQQEILRELNSDVCKYKFLYVTPEKVAKSDVLLRHLESLHTRESLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPTVPVLALTATATMSVKEDVVQALGLANCIIFRQSFNRPNLRYSVIPKTKKCLEDIDNFIKKFHFDQCGIIYCLSRMDCERVAEKLQEYGHKAAFYHGSMEGAQRANIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLPSSCVLYYSYSDYIRVKHMISQGTVDQNSFGSGYGRSNVAASGRILETNVENLLRMVSYCENDVDCRRLLQLIHFGEKFESTNCRKTCDNCSKIQKCIEKDVTEVAKQLVELVKMTGQKFSSAHVLEVYRGSLSQYVKKHRHESLRLHGAGKHLAKGEASRVLRHLVTEDILVEDVKKSDLYGSVSSVLKVNESKAYNLFSGAQTMRLRLPSSVTQSKLGKFEATPAKGSLTSGKQSPPRTDPSAVPQSPVDTNLSAKLYTALRRLRTLLVKEAGDGVMAYHIFGDATMQQISIKVPRTTDELLDINGIGKVKITKYGDRVLETIEATINEHYKSAKTNSSGNDNTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVLKKQNKNPEVIDYRDLGYFDECMDGDIDFDESMMP
Length1185
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.536
Instability index42.17
Isoelectric point8.32
Molecular weight132504.19
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12636
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.48|      19|      35|     969|     987|       1
---------------------------------------------------------------------------
  969-  987 (33.83/19.58)	LFSGAQTMRLRLPSSVTQS
 1001- 1019 (35.65/21.03)	LTSGKQSPPRTDPSAVPQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.50|      12|      35|     231|     242|       2
---------------------------------------------------------------------------
  231-  242 (25.48/14.33)	NCTPQPSVSRCP
  268-  279 (24.02/13.10)	NCNHGLKLGLCP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.76|      16|      28|     143|     159|       3
---------------------------------------------------------------------------
  123-  135 (18.26/ 7.85)	....YASARCTPLHQGV
  143-  159 (27.72/22.06)	DTTrYAGNRFPSHSSGV
  173-  185 (23.78/13.07)	DTS.V.GNN..SHSRGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.73|      35|      39|     814|     851|       4
---------------------------------------------------------------------------
  814-  851 (56.97/49.45)	RileTNVENLLRMVSYCENDVD..CRRLLQLIHF.GEKFES
  855-  892 (51.76/36.42)	R...KTCDNCSKIQKCIEKDVTevAKQLVELVKMtGQKFSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.26|      11|      23|     927|     939|       5
---------------------------------------------------------------------------
  927-  939 (13.88/13.72)	GEASRVLRhlVTE
  953-  963 (18.38/ 9.87)	GSVSSVLK..VNE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.02|      15|      39|     626|     640|       6
---------------------------------------------------------------------------
  626-  640 (25.97/14.77)	EDV...VQALGLANC.IIF
  662-  680 (19.05/ 9.15)	EDIdnfIKKFHFDQCgIIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.92|      18|      40|     379|     415|       7
---------------------------------------------------------------------------
  379-  398 (30.00/50.31)	YNESGGFGNWnsSSLSFDVT
  422-  439 (36.92/12.96)	YTEGSNDKKW..SSRDFPWT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.26|      42|     409|     688|     762|       8
---------------------------------------------------------------------------
  715-  762 (68.92/94.98)	NIQKQWSKDEINIICATvafgmGINKPDVrFVIHHSLPKSIE....GYHQEC
 1127- 1172 (69.34/31.91)	NVQNANSKDEEDFTGST.....GRSKKRV.LKKQNKNPEVIDyrdlGYFDEC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12636 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQGVDENSEYSDTTRYAGNRFPSHSSGVAETGNVVNRQNGADTSVGNNSHSRGIVGISSNHAIGVSKTRESDSTYADGTEED
2) TINEHYKSAKTNSSGNDNTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVLKKQNK
3) YTRPGKTLPLTKENKTFSQHSHNTHVPRASDVNYASARCTP
132
1098
90
213
1156
130










Molecular Recognition Features






MoRF SequenceStartStop




1) KRVLKK
1148
1153