<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12635

Description mediator of RNA polymerase II transcription subunit 25 isoform X1
SequenceMMEKQLIVAVEGTAAVGPFWQTIISDYLDKMIRSFTKLEPIEKKPSAGNWQLAMVVFTVHGSHGACLVRRSGWTTDIDMFFQWLSAIPFSGGGFNDAAVAESLAEALTMFSSLNGSQTQQNVDGQRHCILIAASNPYPLPTPVYHPHMQNVEQSGNIEAHTANRLSDAETVAKEFPQCSVSLSVICPKQLPKLRAIYNAGKRDPQAADPPIDTSKNPNFLVLISENFIEACAAFNRTGMEISALNQILVEMDMSSVAPVSAPAATFDPAVMSQQPISAGSIPSATVNMEPTTVTSVTGPALPHIPTARPTSQLVASLQSASPISVSEEVVPNNEIVNETKPILSGMTQPLRSFSGAAANARILNDVAQAQALVGGTSIGLQSMGGTPILSNMIPGGISSSIPAAPTVLSSGQLAVTSMSGLVPLAGTGQIAQNSVSASSVSIAPSMSGNSNLCVSQLLSNIQGGVSAVMHQNVLSGTGAGMPFGTGTLMSTPRMTQPGHPGMQPLGRNNSTEANIPLSQRQTSATLSSAQSNYVKVWEGDLSGQRQGEPVLITRLQGFRIASASKSLAADWPQTMQIVRLITQEHLNNDVRRLIGKAEIVVFWAMDQHVFLSQLQEKKFCAVIQLPSQAMILSVSDKTCRLIGMLFPENTVVFKPQKLNQQLEAQHPQLEQLLLQQSLPLLQQQRALSRLQQQQPLQQLQQQQHLMPLKRKRNIPLQQQPKIPKLHRQQSPQIQQQQQIPQMQQTEQQQPIIGTCVNQASTGGPRRAQLMSQGQASSRGLPNVP
Length784
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.04
Grand average of hydropathy-0.148
Instability index57.30
Isoelectric point8.66
Molecular weight84291.52
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12635
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.13|      24|      27|     696|     722|       1
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  670-  696 (23.51/ 6.28)	EQLLLQQSL.PL.......LQQQRAL.........srlqqqqpL
  697-  731 (34.41/18.64)	QQLQQQQHLMPLKRKRnipLQQQPKI.........pklhrqqsP
  732-  770 (27.21/ 8.23)	Q.IQQQQQIPQMQQTE....QQQPIIgtcvnqastggprraqlM
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.39|      24|      27|     332|     355|       2
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  332-  355 (43.05/24.84)	NNEIVN...ETKPILSGMTQPLRSFSG
  359-  385 (31.34/15.99)	NARILNdvaQAQALVGGTSIGLQSMGG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.09|      12|      27|     394|     420|       3
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  394-  405 (22.71/ 6.42)	P.........GGIS.SSIPAAP
  423-  444 ( 8.38/ 8.23)	PlagtgqiaqNSVSaSSVSIAP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.95|      25|      49|     258|     282|       4
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  258-  282 (45.88/23.89)	P.....VSAPAATFDP..........AVMSQQPISAGS..IP
  290-  331 (25.06/ 9.62)	PttvtsVTGPALPHIPtarptsqlvaSLQSASPISVSEevVP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|      11|      49|     592|     602|       6
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  592-  602 (18.13/ 9.76)	RLIGKAEIVVF
  613-  623 (16.15/ 7.94)	QLQEKKFCAVI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     298.80|      94|     463|      12|     109|       7
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   12-  109 (154.99/107.19)	GTAAVGPFWQ.TIISdYlDKMIR.SFTKLEPIEKKPSA.GNWQLAMVVFTVH.GSHGACLVRrsGWTTDIDMFFQWLSAIPFSGGGFNDAAVAESLAEAL..TM
  476-  575 (143.81/86.38)	GTGAGMPFGTgTLMS.T.PRMTQpGHPGMQPLGRNNSTeANIPLSQRQTSATlSSAQSNYVK..VWEGDLSGQRQGEPVLITRLQGFRIASASKSLAADWpqTM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12635 with Med25 domain of Kingdom Viridiplantae
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