<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12628

Description heat shock cognate 70 kDa protein 2
SequenceMAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVGFTDSERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFSDASVQSDMKLWPFKVIPGAGDKPMIVVNYKGEEKQFAAEEISSMVLIKMKEIAEAFLGTTVKNAVVTVPAYFNDSQRQATKDAGVISGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFKRKSKKDITGNPRALRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSTVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERTRTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKEEIEKMVQEAEKYKSEDEEHKKKVEAKNALENYSYNMRNTVKDEKIASKLSAEDKKKIEDAIEEAIQWLDGNQLAEADEFEDKMKELEGICNPIIAKMYQGAGGDMGGAMDDEGPAPSGGGAGPKIEEVD
Length648
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.415
Instability index33.56
Isoelectric point5.08
Molecular weight70967.60
Publications
PubMed=23773524

Function

Annotated function Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. 
ECO:0000256	ARBA:ARBA00003955
GO - Cellular Component
endoplasmic reticulum lumen	GO:0005788	IEA:UniProtKB-SubCell
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12628
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.82|      16|      21|      13|      32|       1
---------------------------------------------------------------------------
   13-   28 (33.53/25.07)	DLG..TTYSCVGVWQHDR
   35-   52 (26.29/ 9.95)	DQGnrTTPSYVGFTDSER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.11|      45|     189|     170|     218|       2
---------------------------------------------------------------------------
  170-  218 (62.52/50.95)	GLNVMRIINePTaAAIAYGLDKKATSV.GEKNVLIFDLggGTFDVSLLTI
  362-  407 (71.59/42.63)	GKELCKSIN.PD.EAVAYGAAVQAAILsGEGNEKVQDL..LLLDVTPLSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.11|      25|     398|     102|     169|       5
---------------------------------------------------------------------------
   59-   88 (34.03/65.30)	KNQVAMNPtnTVF.DAKRLIGRrfsDASVQS
  144-  169 (39.08/10.75)	KNAVVTVP..AYFnDSQRQATK...DAGVIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12628 with Med37 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GAGGDMGGAMDDEGPAPSGGGAGPKIEEVD
2) KEEIEKMVQEAEKYKSEDEEHKKKVEAKNA
619
518
648
547










Molecular Recognition Features






MoRF SequenceStartStop




1) AGPKIEEVD
640
648