<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12627

Description U-box domain-containing protein 34-like isoform X2
SequenceMKVNVDGDTGGSPTSTTATVTVAVAVKSAEGKGSQRAVKWAVEKLLPKAHRFVFIHVMPTITTIPTPSGESTLVDELEANVVKLYIEDKRAQCEEIFIPFKILCKRKNVETLVLEGNNPATVLLKYVNDSGIKSLVLGSYSPNYFSRKLKGSSVPSIILKHAPECCDVYVVSSNKLMTNSLNPLLATGDLPTINKQKSSASSASIDGVSHSRSSSLASSHLNFPAFLDGNSSNYASLQQKLNQNLEDVTTGLETVKECHISTSSEQLDIQDEVERVRLELQTTLAMYNQTCEDLIHTQNKVQLFSSEYLEEYRKVNAAKKREENLRKIAAEEKERHLEAEKEVETARKLLSEETYERQIAELKALQQSLEKKKTVDALLSSDHRYRRLTREEIEVATDYFCESKMIGEGAYGKVYKGDLDHTPVAIKVLCSDASEKKEEFLREVEVLSQLHHPHIVLLLGACPENGCLVYEYMENGSLEDCILERNSKPFPWFSRFRILFEVACALAFLHNSKPEPIVHRDLKPGNILLDKNFVSKIGDVGLAKIISDVVPESVTEYRNSVLAGTLGYMDPEYQRTGTLRPKSDLYAFGIITLQLLAACRPNGLIMVFENAINSNLLVDILDKSVPDWPLMEAEELARMALKCCSLRCRDRPDLETEVLPLLKRLSEFADMRTKVEKNIIQAPSPYLCPIVQEVMEDPQIAADGFTYEHRAIKLWLTRHSVSPVTKQILQHKMVTPNRTLRLAIQEWRSQVTSFRPRS
Length758
PositionTail
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.293
Instability index46.01
Isoelectric point6.20
Molecular weight85189.69
Publications
PubMed=23773524

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12627
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.04|      16|      20|      99|     114|       1
---------------------------------------------------------------------------
   99-  114 (27.74/23.06)	PFKILCKRKN...VETLVL
  119-  137 (19.29/13.34)	PATVLLKYVNdsgIKSLVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.39|      19|      27|     307|     333|       2
---------------------------------------------------------------------------
  313-  332 (26.02/27.32)	RKVNAAKKREENlRKIAAEE
  335-  353 (30.37/ 8.24)	RHLEAEKEVETA.RKLLSEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.68|      44|     135|     448|     491|       3
---------------------------------------------------------------------------
  448-  491 (84.20/52.52)	SQLHHPHIV..LLLGACPENG.CLVYEYMENGSLEDCILERNSKPFP
  583-  629 (70.48/42.86)	SDLYAFGIItlQLLAACRPNGlIMVFENAINSNLLVDILDKSVPDWP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.63|      15|      15|     200|     214|       4
---------------------------------------------------------------------------
  200-  214 (26.49/18.50)	ASS.....ASIDGVSHSRSS
  217-  236 (21.14/13.32)	ASShlnfpAFLDGNSSNYAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.54|      24|     330|      29|      52|       6
---------------------------------------------------------------------------
   29-   52 (42.67/34.26)	AEGKGSQRAV..KWAVEKLLPKAHRF
  360-  385 (34.86/26.51)	AELKALQQSLekKKTVDALLSSDHRY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.04|      17|      27|     238|     262|       7
---------------------------------------------------------------------------
  238-  254 (27.31/29.27)	QQKLNQNLEDVTTGLET
  266-  282 (26.73/ 9.66)	QLDIQDEVERVRLELQT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12627 with Med32 domain of Kingdom Viridiplantae
Unable to open file!