<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12620

Description mediator of RNA polymerase II transcription subunit 33A isoform X1
SequenceMEVSMDCSLWDSVLELTKVSQEKGGDPLVWAIQVSSCLSSAGVSLPSLELANFLVSHICWENNLPIVWKFLEKALVLKIVSPIIVFPLLSSRVIQNRRSRPAAFRLYMELLRRHIFTLKIHVNMQSYKKIVSFLNSVLYLTEIFGMHADEPGVLVVEIIFSIVWQLLDASLDDEGLLQLTPEKKSRWPTKPEDMEIDGCITDMERNEHKERLKNLNTLLAIELIAQFLQNKVTARILYLACQNMPIHWGAFVQRIQLLAGNSSALQSSSVISPEALLQLASDAHNLIKTNSLQERYVRSTLRSLATCAGLCFGSSRSSLWLPLDLFLEDAMDGSQVNATSAIEIITDLVKSLQAINATTWHETFLGLWMAALRLVQRERDPIEGPMPRLDTRLCMLFSIITLVVADLIEEEESEACDEIESSIDRHMKNQVAGTRRRDIVSCLQSLGDYQSLLTPPQAITTAANQAAAKAMMFRSGINSNSSYFECINMKDLPINCSGNLYHLIVEACIARNLLDTSAYFWPGYVNGRMNQLPHSMPTQVPGWSSFMKGAPLTQAMINALVSAPASSLAEMEKIFEMAVKGADDEKIAAATILCGASLIHGWNIQEHTVNFITRLLSPPVPTDYSGKDSHLIGYAPTLNVLLVGIAPVDCVQIFSLHGMVPQLAASLMTICEVFGSCAPNISWTLTTGEDISVHAVFSNAFALLLKLWRFNHPPIEYRVGDVPPVGCQLTPEYLLLMRNSHLVSSGDMLKDPNRRRLAAVASSSSPNPIFVDSFPKLRVWYRQHLACIASTLSGLVNGTLVCQTVDLLLNMMFKKINGGSQSLISITSGSSSSSGTGSEDTSPRPKLPAWDILEAVPFVVDAALTACAHGRLSPRELCTGLKDLADFLPASLATIVSYFSAEVTRGVWKPVFMNGTDWPSPAANLSNVEEQIKKILAATGVDVPSLAAGGSSPAILPLPLAAFVSLTITYKLDKASQRFLNLAGPALESLAAGCPWPCMPIVASLWTQKAKRWSDFLVFSASRTVFLNNNHAVIQLLKSCFMTTLGLNSSSISSNGGIGALLGHGFGSHFYGGISPVAPGILYLRVYRSIRDIMFLREEIVSLLMQSISDIAHSELPRQRLGKLKKSKNGKKFGNVSLAKTMTRVKLAALLGASLLWLSGGSGLVQSLIKETLPSWFLSVHSSNQGGEGGLVPMLKGYALAYFAVLCGAFASGVDSLSMASKRRPKIIGRHVEFIASVLDGKISLGCDPATWHAYVSGFVSLMVGCTPTWVFEVDAELLKRLSKGLRQWHEEDLALALLSIGGVGTMGSAAELIMEVSS
Length1319
PositionTail
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy0.211
Instability index48.48
Isoelectric point6.85
Molecular weight143901.48
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12620
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     213.16|      79|     160|     972|    1054|       2
---------------------------------------------------------------------------
  972- 1024 (75.22/43.12)	...............................LDKASQRFLN...............................................................................................LAGPALE...........................SLAAGC.P.WpCMPIVASLWTQKAK...RWSDFLVFSASRT
 1028- 1054 (18.58/ 7.08)	NNNHAVIQLLKSCFMTTLGLNSSSISS........................................................................................................................................................................................
 1150- 1185 (40.23/16.77)	.........................................nggigallghgfgshfyggispvapgilylrvyrsirdimflreeivsllmqsisdiahselprqrlgklkkskngkkfgnvslaktmtrvklaaLLGASLL...........................WLSGGS.......GLVQSLIKETLP...SW..FLSVHSSNQ
 1186- 1291 (79.13/38.66)	GGEGGLVPMLKGYALAYFAVLCGAFASgvdsLSMASKRRPK...............................................................................................IIGRHVEfiasvldgkislgcdpatwhayvsgfvSLMVGCtPtW.VFEVDAELLKRLSKglrQWHE.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.69|      19|     639|     281|     326|       6
---------------------------------------------------------------------------
  303-  326 (27.37/47.02)	SLAtcAGlcfGSSRSSLWLPLDLF
  945-  963 (36.32/ 7.64)	SLA..AG...GSSPAILPLPLAAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     228.75|      74|     567|     178|     258|      12
---------------------------------------------------------------------------
  178-  258 (116.55/107.77)	QLTPEkkSRWPTKPEDMEIDGcitDMERNEHKERLKNLNTLLAIELIaqFLQNKVTARILY...LACQNMPIH...WGAFV.QRIQLL
  728-  808 (112.19/81.82)	QLTPE..YLLLMRNSHLVSSG...DMLKDPNRRRLAAVASSSSPNPI..FVDSFPKLRVWYrqhLACIASTLSglvNGTLVcQTVDLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12620 with Med33 domain of Kingdom Viridiplantae
Unable to open file!