<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12613

Description mediator of RNA polymerase II transcription subunit 25 isoform X2
SequenceMVVFTVHGSHGACLVRRSGWTTDIDMFFQWLSAIPFSGGGFNDAAVAESLAEALTMFSSLNGSQTQQNVDGQRHCILIAASNPYPLPTPVYHPHMQNVEQSGNIEAHTANRLSDAETVAKEFPQCSVSLSVICPKQLPKLRAIYNAGKRDPQAADPPIDTSKNPNFLVLISENFIEACAAFNRTGMEISALNQILVEMDMSSVAPVSAPAATFDPAVMSQQPISAGSIPSATVNMEPTTVTSVTGPALPHIPTARPTSQLVASLQSASPISVSEEVVPNNEIVNETKPILSGMTQPLRSFSGAAANARILNDVAQAQALVGGTSIGLQSMGGTPILSNMIPGGISSSIPAAPTVLSSGQLAVTSMSGLVPLAGTGQIAQNSVSASSVSIAPSMSGNSNLCVSQLLSNIQGGVSAVMHQNVLSGTGAGMPFGTGTLMSTPRMTQPGHPGMQPLGRNNSTEANIPLSQRQTSATLSSAQSNYVKVWEGDLSGQRQGEPVLITRLQGFRIASASKSLAADWPQTMQIVRLITQEHLNNDVRRLIGKAEIVVFWAMDQHVFLSQLQEKKFCAVIQLPSQAMILSVSDKTCRLIGMLFPENTVVFKPQKLNQQLEAQHPQLEQLLLQQSLPLLQQQRALSRLQQQQPLQQLQQQQHLMPLKRKRNIPLQQQPKIPKLHRQQSPQIQQQQQIPQMQQTEQQQPIIGTCVNQASTGGPRRAQLMSQGQASSRGLPNVP
Length731
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.04
Grand average of hydropathy-0.156
Instability index58.95
Isoelectric point8.70
Molecular weight78327.58
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12613
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.13|      24|      27|     643|     669|       1
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  617-  643 (23.51/ 6.97)	EQLLLQQSL.PL.......LQQQRAL.........srlqqqqpL
  644-  678 (34.41/20.78)	QQLQQQQHLMPLKRKRnipLQQQPKI.........pklhrqqsP
  679-  717 (27.21/ 9.15)	Q.IQQQQQIPQMQQTE....QQQPIIgtcvnqastggprraqlM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.39|      24|      27|     279|     302|       2
---------------------------------------------------------------------------
  279-  302 (43.05/23.68)	NNEIVN...ETKPILSGMTQPLRSFSG
  306-  332 (31.34/15.29)	NARILNdvaQAQALVGGTSIGLQSMGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.44|      35|      36|     196|     231|       4
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  151-  208 (34.89/15.45)	PQAA.DPPIdTSKNPnflvlISE..NFIEAcAafnrtgmeisalnqilVEMDMS.SVAPVSA
  209-  245 (51.61/30.64)	PAATfDPAV.MSQQP.....ISA..GSIPS.A...............tVNMEPT.TVTSVTG
  246-  278 (34.94/15.49)	PAL...PHI.PTARP.....TSQlvASLQS.A................SPISVSeEVVP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|      11|      49|     539|     549|       5
---------------------------------------------------------------------------
  539-  549 (18.13/10.68)	RLIGKAEIVVF
  560-  570 (16.15/ 8.73)	QLQEKKFCAVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.65|      35|      66|     394|     429|       6
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  394-  429 (54.88/35.28)	SGNSNLCVSQLLSNIQGGVSAVMHQNvLSGTGAGMP
  432-  463 (52.49/29.40)	TG.TLMSTPRMTQPGHPGMQPLGRNN...STEANIP
  465-  496 (50.29/27.84)	SQRQ...TSATLSSAQSNYVKVWEGD.LSGQRQGEP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12613 with Med25 domain of Kingdom Viridiplantae
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