<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12601

Description U-box domain-containing protein 34-like isoform X4
SequenceMKLKGSSVPSIILKHAPECCDVYVVSSNKLMTNSLNPLLATEGDLPTINKQKSSASSASIDGVSHSRSSSLASSHLNFPAFLDGNSSNYASLQQKLNQNLEDVTTGLETVKECHISTSSEQLDIQDEVERVRLELQTTLAMYNQTCEDLIHTQNKVQLFSSEYLEEYRKVNAAKKREENLRKIAAEEKERHLEAEKEVETARKLLSEETYERQIAELKALQQSLEKKKTVDALLSSDHRYRRLTREEIEVATDYFCESKMIGEGAYGKVYKGDLDHTPVAIKVLCSDASEKKEEFLREVEVLSQLHHPHIVLLLGACPENGCLVYEYMENGSLEDCILERNSKPFPWFSRFRILFEVACALAFLHNSKPEPIVHRDLKPGNILLDKNFVSKIGDVGLAKIISDVVPESVTEYRNSVLAGTLGYMDPEYQRTGTLRPKSDLYAFGIITLQLLAACRPNGLIMVFENAINSNLLVDILDKSVPDWPLMEAEELARMALKCCSLRCRDRPDLETEVLPLLKRLSEFADMRTKVEKNIIQAPSPYLCPIVQEVMEDPQIAADGFTYEHRAIKLWLTRHSVSPVTKQILQHKMVTPNRTLRLAIQEWRSQVTSFRPRS
Length613
PositionTail
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.355
Instability index50.35
Isoelectric point5.84
Molecular weight69442.68
Publications
PubMed=23773524

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12601
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.71|      27|      27|     162|     188|       1
---------------------------------------------------------------------------
  162-  188 (41.57/27.58)	EYLEEYRKVNAAKKREENLRKIAAEEK
  190-  209 (23.39/12.43)	......RHLEAEKEVETA.RKLLSEET
  222-  247 (34.76/21.90)	QSLEKKKTVDALLSSDHRYRRLTREE.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.68|      44|     135|     303|     346|       3
---------------------------------------------------------------------------
  303-  346 (84.20/56.23)	SQLHHPHIV..LLLGACPENG.CLVYEYMENGSLEDCILERNSKPFP
  438-  484 (70.48/45.93)	SDLYAFGIItlQLLAACRPNGlIMVFENAINSNLLVDILDKSVPDWP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.33|      22|     476|      13|      39|       4
---------------------------------------------------------------------------
   13-   39 (30.41/31.15)	LKhapeCCDVYVVSSNKLMTNSLnPLL
  496-  517 (41.92/24.64)	LK....CCSLRCRDRPDLETEVL.PLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12601 with Med32 domain of Kingdom Viridiplantae
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