<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12594

Description mediator of RNA polymerase II transcription subunit 25-like
SequenceMVADKQLIVAVEGTAALGPFWHTIVSDYLDKIIRSFFGAESTSQKPSAANVEVSLVMFNAHGSYSACLVQRSGWTRDMDIFFQWLSAIPFSGGGFSDAAVAEGLGEALMMFSSPNGNQSQQNMEGKKHCLLISASNPYPLPTPVYRPQMQKLEQNENTETQTDSRLSDAETVAKAFPQCSVSLSVICPKQLSKLRAVYNAGKRNPRAADPPIDTAKNPNFLVLISENFIEARAAFSRSGMTNLTSNQTPIKMDVPSIPPVSVPPSISNSAANGSVMSRQPISAGNIPPATVKIEPTTVTSMNGPAFSHIPSVRPALQPVPSLQTSSPLSVSQEMASHNENVQEMKPIVSGMTQSLRPVAAAAANVRILNDVAQARQAIAGATSIGLQSMGGTPMLSSMISSGMASSVPSAQTVFSSGQSGVTTVSGSVPLSGSGQNTQNSAPASFTSTAPSMSGNPNISISQPLSNNQGGISMAGQTVPGMCQGNLPGTQMMPSGTGMNQNMLTGLGATGMPSGTGTMMPTPGISQQGQPGMQPVGNSTGANMPLSQQQTPAALPSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASESLAANWPPTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLSQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQIPSQQQQQQQLQAQHPQLQQQQLSQQQQHISQLQQQQLSQQQQHISQLQQQPLQQLQQQQPLMQQQQQMHQMQQQQLPQMQQQQQISQMQQQQQIPQMQQPQQQQPMVGTGVNQAYMQGPARSQLMSQGQVSSQGLPTMPGSGFMN
Length828
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.04
Grand average of hydropathy-0.365
Instability index60.92
Isoelectric point9.07
Molecular weight88790.72
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12594
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     123.27|      16|      16|     745|     760|       1
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  686-  698 (26.24/ 6.31)	QQQQQQ..QL.QAQH.P
  729-  743 (28.95/ 7.78)	QLQQQPLQQL.QQQQ.P
  745-  760 (37.51/12.41)	MQQQQQMHQM.QQQQLP
  762-  778 (30.56/ 8.65)	MQQQQQISQMqQQQQIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     334.94|      50|      50|     444|     493|       2
---------------------------------------------------------------------------
  254-  295 (36.41/11.82)	.....VPSI.....PPVS..VPPSI...........SNSaANG.SVMSRQ..P............ISAGNIPpaTV.K.IEP
  308-  346 (52.36/20.82)	HIPSVRPALQ..PVPSLQ..TSSPL...........SVS.Q.......................EMASHNEN..VQ.E.MKP
  388-  442 (28.96/ 7.61)	.......SMG..GTPMLSsmISSGMassvpsaqtvfSSG.QSG.VTTVSGSVP.............LSGSGQ..NT.QnSAP
  444-  493 (94.34/44.52)	SFTSTAPSMS..GNPNIS..ISQPL...........SNN.QGG.ISMAGQTVP...........GMCQGNLP..GT.Q.MMP
  494-  520 (41.01/14.42)	SGTG....M....N........Q...............N.M.....LTGLGAT...........GMPSGT....GT...MMP
  521-  577 (34.86/10.95)	....T.PGISqqGQP..G..M.QPV...........GNS.TGAnMPLSQQQTPaalpsaqskyvKVWEGNLS..GQrQ.GQP
  579-  620 (47.00/17.80)	FIT....RLE..GYRSAS..ASESL...........AAN.WPP..TM..QIVR...........LISQDHMN..NK.Q.YV.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.24|       9|      62|     714|     724|       4
---------------------------------------------------------------------------
  714-  724 (14.24/ 9.46)	QLQQQQlsQQQ
  779-  787 (20.00/ 7.42)	QMQQPQ..QQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.60|      13|      29|     788|     800|       6
---------------------------------------------------------------------------
  788-  800 (23.60/10.84)	PMVGTGVNQAYMQ
  807-  819 (19.99/ 7.97)	LMSQGQVSSQGLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.31|      28|      39|     139|     177|       8
---------------------------------------------------------------------------
  140-  168 (44.74/38.84)	LPTPVYRP.QMQKLEQNENTeTQTDSRLSD
  181-  209 (42.56/13.46)	VSLSVICPkQLSKLRAVYNA.GKRNPRAAD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12594 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FSRSGMTNLTSNQTPIKMDVPSIPPVSVPPSISNSAANGSVMSRQPISAGNIPPATVKIEPTTVTS
2) QISQMQQQQQIPQMQQPQQQQPMVGTGVNQAYMQGPARSQLMSQGQVSSQGLPTMPGSGFMN
3) SVPSAQTVFSSGQSGVTTVSGSVPLSGSGQNTQNSAPASFTSTAPSMSGNPNISISQPLSNNQGGISMAGQTVPGMCQGNLPGTQMMPSGTGMNQNMLTGLGATGMPSGTGTMMPTPGISQQGQPGMQPVGNSTGANMPLSQQQTPAA
4) VRPALQPVPSLQTSSPLSVSQEMASHNENVQEMKPIVSGMTQ
235
767
406
312
300
828
553
353










Molecular Recognition Features






MoRF SequenceStartStop




NANANA