<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12592

Description pre-mRNA-processing protein 40C-like isoform X1
SequenceMASPAWLPQEMQSSSSQTSGMSLATGEPTTSSSTPNADSTQEAVQGKFIPPPGYSAGRASFSYVNASVPSGSSQQSSSSPVIPSTSSGSSASLQPPIPGQSANVGSSFSYNISHADNNFSRGLQFSTSPLRPVSPNQLVDVKNSSPAASLQPPLPLVSTRLSSFIPGSAAPAASPLSGSNLSFNGSPQMVQTDQTMKPLQNRRVDIAHEMGAMTSPPSVMQSFSQAGHMSSGSSTAAFPTSHLGSPNIRMPHAPQFQVPAGVPRSPVTPGPPGLGPVIPSSSNVTATASPGGPSLSLRPNGPPVPVLANPPVQQQIYSPYLSASPMAPTQGPWLQPSPVTTMLRPPFPSHPAGFAVPFPLSATGAPRSSATLPDTRPPGVASVATPPGVPTTATQSIPALGLQPELPPGVDSAKHVNDADTIEGAPTSEQLETWTAHRTETGAIYYYNSLTGESTYEKPAGFSGEPAKVAAQPTPVSWEKLAGTDWALVTTNDGQKYYYNTKTKLSSWQIPNDVTELKKKHEADALQAQSTSMPNANALTEKGSSPISLSIPAVNTGGRDATTLRSSVVPGSSALDLVKKKLMDAGATAAASSPTPASSGVISSELNGSEALESTARAPQKENSKDKSKEANDNGNMSESSSDSEDDESVPTKEDCIIQFKEMLKERGVAPFSKWEKELPKIVFDPRFKAIPSYSARKALFEHYVKTRADEERKEKRAAQKAAVEGFKHLLEEAKEVYLVT
Length741
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.465
Instability index62.29
Isoelectric point6.30
Molecular weight77492.36
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12592
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     372.06|      55|      56|      79|     133|       1
---------------------------------------------------------------------------
   62-  108 (77.94/23.96)	SY....VNASVPSG....SSQ.QSSS.....SP..VIPSTS........SGS..SASLQ...PP...........I.PG.QSA..........................NVGSSF
  109-  176 (74.96/22.77)	SYNISHADNNFSRGLQFSTSP.LRPV.....SPnqLVDVKN........SSP..AASLQ...PPlplvstrlssfI.PG.SAA..........................PAASPL
  247-  312 (66.30/19.32)	NIRMPHAP.QFQVPAGVPRSP.VTPG.ppglGP..VIPSSSnvtataspGGP..SLSLRpngPP...........V.P..VLA..........................N..PPV
  313-  358 (62.07/17.64)	QQQI......YSPYL..SASP.MAPTqgpwlQP..S.PVTT...............MLR...PP...........F.PS.HPA..........................GFAVPF
  359-  445 (39.78/ 8.77)	PLSATGAPRS.SATLPDTRPPgVASV...atPP..GVPTTA........TQSipALGLQ...PE...........LpPGvDSAkhvndadtiegaptseqletwtahrtETGAIY
  530-  574 (50.99/13.23)	STSMPNANALTEK..G..SSP.ISLS.....IP..AV.NTG........GRD..ATTLR..sSV...........V.PG.SSA................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.74|      14|      49|     446|     459|       3
---------------------------------------------------------------------------
  446-  459 (25.81/19.32)	YYNSLTGESTYEKP
  498-  511 (24.93/18.36)	YYNTKTKLSSWQIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.12|      21|      23|     594|     614|       4
---------------------------------------------------------------------------
  594-  614 (35.21/20.40)	PTPASS..........GVISSELNGSEALES
  619-  649 (28.91/15.26)	PQKENSkdkskeandnGNMSESSSDSEDDES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.07|      31|     210|       1|      35|       5
---------------------------------------------------------------------------
    1-   35 (48.24/32.61)	MASPawlPQEMQSSsSQTSGMSLATGE...PTTSSSTP
  213-  246 (54.84/25.55)	MTSP...PSVMQSF.SQAGHMSSGSSTaafPTSHLGSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12592 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELKKKHEADALQAQSTSMPNANALTEKGSSPISLSIPAVNTGGRDATTLRSSVVP
2) MASPAWLPQEMQSSSSQTSGMSLATGEPTTSSSTPNADSTQEAVQGKFIPP
3) MDAGATAAASSPTPASSGVISSELNGSEALESTARAPQKENSKDKSKEANDNGNMSESSSDSEDDESVPTK
4) SPLSGSNLSFNGSPQMVQTDQTMKPLQNRRVDIAHEMGAMTSPPSVMQSFSQAGHMSSGSSTAAFPTSHLGSPNIRMPHAPQFQVPAGVPRSPVTPGPPGLGPVIPSSSNVTATASPGGPSLSLRPNGPPVPVLANPPV
5) SRGLQFSTSPLRPVSPNQLVDVKNSSPAASLQPP
6) SSQQSSSSPVIPSTSSGSSASLQPPIPGQSANVGSSFSYN
7) YSPYLSASPMAPTQGPWLQPSPVTTMLRPPFPSHPAGFAVPFPLSATGAPRSSATLPDTRPPGVASVATPPGVPTTATQSIPALGLQPELPPGVDSAKHVNDADTIEGAPTSEQLETWT
516
1
583
174
120
72
317
570
51
653
312
153
111
435










Molecular Recognition Features






MoRF SequenceStartStop




1) IYSPYL
2) LVKKKLM
3) MASPAWL
4) RASFSYV
5) VQGKFIPPPGY
316
577
1
58
44
321
583
7
64
54