<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12570

Description pre-mRNA-processing protein 40A isoform X2
SequenceMASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQQGQPFASSISASPQYRPVGQTSNAGMPPGHHSQIPQFSQPMQQFPPRPNQPGHGILLSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTFAPPPFAHALSGLNMPSQVQSSSQMHVPSFPSGGQPWLSSGSQNTPVTAPTLLTNQQLSAIAPSVPAGTASPQNASDWQEYEAADGRRYYYNKITKQSSWEKPLELMTPLERADASTVWKEFTTADGRKYYYNKETKQSKWTIPEELKLARELAEKSAGQVVQTGASTTSGVQVTAAVTSTEQPSAVTPVSSTPSSTVSGVASSPVPVTSAVSDHASPLVVSGSSAIPAVTPAMPSSSGVSSPAVSGSTGSAALANASQTQMSGFENLSPQVSSSLSGASIQDIEEAKKGMAVAGKVNVVPAEEKTTEEEPFLYATKQEAKNAFKALLEFANVESDWTWEQTMRVIINDKRYGALKTLGERKQAFNEYLMQRKKQEAEERRHRQRKAKEEFTKMLEESKELISSTRWSKAVTMFEDDERFKAVEREADREDLFRNYLVDLQKKERAKAQEEYRQNRLEYRHFLETCGFIKVDTQWRKVQDLLEDDERCLRLEKIDRLDIFQEYIRDLEKEDEEQRKLQKEQLRRTERKNRDAFRKMMEEQITAGTLTAKTSWRDYCQMVKESVAYQAVASNTSGSTPKDLFEDVVEELEKQYHEDKIRVKDVVKSEKITISSTWTFEDFKATILEGIGSPSIHDVNLQLIFEDLIERAKEKEEKETKKRQRLAKDFTDKLSTIKEITASSSWEECKELVEDTSEFRAIGEETISRAVFEEYVAWLQEKAKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKERDKEKERGNERATKDEADSESMDVTDNYEPKEERKREKDRERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDELASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGGYEELEDGELGEDGES
Length1044
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.084
Instability index61.02
Isoelectric point6.08
Molecular weight118512.12
Publications
PubMed=23773524

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12570
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.69|      23|      23|     852|     874|       1
---------------------------------------------------------------------------
  852-  872 (30.45/11.65)	...KEKERRREEEKAKKEK.........EKEEK
  873-  889 (21.30/ 6.01)	EKrKDKERR......EKER.........EKE.K
  950-  981 (24.95/ 8.26)	DE.KEEPERDKERKHRKRHhssndelasDKDEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     118.85|      23|      23|      61|      83|       2
---------------------------------------------------------------------------
    6-   35 (28.08/11.99)	PP...............SGPQplwpPSVGS......TPP..QgFgsS..FPMQQG
   55-   77 (43.46/22.66)	SN...............AGMP....PGHHS......QIP..Q.F..S..QPMQQF
   78-  110 (26.33/10.77)	PP...............RPNQ....PGHGIllsqaiQMPfiQ.S..SmpQPQQVI
  178-  213 (20.98/ 7.06)	P.vtaptlltnqqlsaiAPSV....PAGTA......S.P..Q.N..A..SDWQEY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.44|      37|      38|     216|     252|       3
---------------------------------------------------------------------------
  216-  249 (61.40/35.46)	.......ADGRRYYYNKITKQSSWEKPLELMTPLERADAST
  250-  290 (60.56/34.86)	VWKefttADGRKYYYNKETKQSKWTIPEELKLARELAEKSA
  306-  329 (36.48/18.07)	VTA....AV............TSTEQP.SAVTPVSSTPSST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     164.71|      23|      23|     596|     618|       4
---------------------------------------------------------------------------
  488-  511 (17.26/ 6.32)	KTLGerkqaFNEYLMQ.RKKQ...EAEE
  512-  531 (26.60/14.07)	RRHR.....QRKAKEEFTK...MLEESK
  535-  550 (21.81/10.09)	SS............TRWSKAVTMFEDDE
  596-  618 (39.61/24.87)	ETCG.....FIKVDTQWRKVQDLLEDDE
  624-  644 (18.52/ 7.36)	EKID.......RLDIFQEYIRDLEKEDE
  656-  672 (18.15/ 7.06)	RTER.......KNRDAFRK...MMEEQ.
  674-  695 (22.75/10.87)	.TAG.....TLTAKTSWRDYCQMVKESV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     118.60|      20|      23|     111|     130|       5
---------------------------------------------------------------------------
  111-  129 (30.00/19.09)	......PPLNS..HMPGVSGAGNPFSS
  130-  154 (26.12/15.45)	SytfapPPFAH..ALSGLNMPSQVQSS
  155-  171 (21.60/11.21)	S..........qmHVPSFPSGGQPWLS
  360-  378 (23.93/13.40)	......PAVTP..AMPSSSGVSSPAVS
  379-  395 (16.95/ 6.85)	......GS..T..GSAALANASQTQMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.77|      18|      23|     968|     990|       6
---------------------------------------------------------------------------
  922-  947 (21.30/11.62)	EERKrekdRERKH.......rkrhHI..SNDEVTS
  982- 1012 (20.47/10.81)	EESK....RSRRHssdrkkskklaHSpeSDGESRH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     181.84|      47|      74|     718|     764|       7
---------------------------------------------------------------------------
  700-  724 (29.30/15.73)	...........VASN.......TSGSTPKD.......LFEDV....VEELEKQY
  725-  771 (80.19/57.78)	HEDKI.RVKDVVKSEKI...TISSTWTFEDFK...ATILEGIGSPSIHDVNLQL
  773-  815 (44.14/27.99)	FEDLIeRAKE..KEEKE...TKKRQRLAKDFTdklSTIKE.ITASSSWE.....
  816-  849 (28.22/14.83)	.ECKE.LVEDTSEFRAIgeeTISRA.VFEEYV...AWLQE..............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.27|      14|      23|     556|     569|       8
---------------------------------------------------------------------------
  556-  569 (24.23/13.03)	EREADREDLFRNYL
  576-  589 (23.03/12.04)	ERAKAQEEYRQNRL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12570 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELAEKSAGQVVQTGASTTSGVQVTAAVTSTEQPSAVTPVSSTPSSTVSGVASSPVPVTS
2) KERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKERDKEKERGNERATKDEADSESMDVTDNYEPKEERKREKDRERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDELASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGGYEELEDGELGEDGES
3) LSGLNMPSQVQSSSQMHVPSFPSGGQPWLSSGSQNTPVTAPTLLTNQ
4) MASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQQGQPFASSISASPQYRPVGQTSNAGMPPGHHSQIPQFSQPMQQFPPRPNQPGHGILLSQAIQMPF
5) QSSMPQPQQVIPPLNSHMPGVSGAGNPFSS
284
854
142
1
100
342
1044
188
98
129










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELEDGEL
2) ILLSQAIQ
3) KKSKKLAHS
4) SRHKRHRRDHRD
1029
88
995
1010
1038
95
1003
1021