<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12568

Description pre-mRNA-processing protein 40A isoform X1
SequenceMASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQFRPAVSTQQGQPFASSISASPQYRPVGQTSNAGMPPGHHSQIPQFSQPMQQFPPRPNQPGHGILLSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTFAPPPFAHALSGLNMPSQVQSSSQMHVPSFPSGGQPWLSSGSQNTPVTAPTLLTNQQLSAIAPSVPAGTASPQNASDWQEYEAADGRRYYYNKITKQSSWEKPLELMTPLERADASTVWKEFTTADGRKYYYNKETKQSKWTIPEELKLARELAEKSAGQVVQTGASTTSGVQVTAAVTSTEQPSAVTPVSSTPSSTVSGVASSPVPVTSAVSDHASPLVVSGSSAIPAVTPAMPSSSGVSSPAVSGSTGSAALANASQTQMSGFENLSPQVSSSLSGASIQDIEEAKKGMAVAGKVNVVPAEEKTTEEEPFLYATKQEAKNAFKALLEFANVESDWTWEQTMRVIINDKRYGALKTLGERKQAFNEYLMQRKKQEAEERRHRQRKAKEEFTKMLEESKELISSTRWSKAVTMFEDDERFKAVEREADREDLFRNYLVDLQKKERAKAQEEYRQNRLEYRHFLETCGFIKVDTQWRKVQDLLEDDERCLRLEKIDRLDIFQEYIRDLEKEDEEQRKLQKEQLRRTERKNRDAFRKMMEEQITAGTLTAKTSWRDYCQMVKESVAYQAVASNTSGSTPKDLFEDVVEELEKQYHEDKIRVKDVVKSEKITISSTWTFEDFKATILEGIGSPSIHDVNLQLIFEDLIERAKEKEEKETKKRQRLAKDFTDKLSTIKEITASSSWEECKELVEDTSEFRAIGEETISRAVFEEYVAWLQEKAKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKERDKEKERGNERATKDEADSESMDVTDNYEPKEERKREKDRERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDELASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGGYEELEDGELGEDGES
Length1052
PositionUnknown
OrganismNicotiana sylvestris (Wood tobacco) (South American tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.078
Instability index60.86
Isoelectric point6.13
Molecular weight119399.11
Publications
PubMed=23773524

Function

Annotated function 
ECO:0000256	
ECO:0000256
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP12568
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.37|      35|      38|     212|     246|       1
---------------------------------------------------------------------------
  212-  246 (72.36/46.84)	PQNASD....WQEYEAADGRRYYYNKITKQSSWEKPLEL
  249-  287 (64.01/40.53)	PLERADastvWKEFTTADGRKYYYNKETKQSKWTIPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      97.90|      23|      23|     860|     882|       2
---------------------------------------------------------------------------
  860-  880 (30.45/12.75)	...KEKERRREEEKAKKEK.........EKEEK
  881-  897 (21.30/ 6.58)	EKrKDKERR......EKER.........EKE.K
  898-  919 (21.20/ 6.52)	ERdKEKE..RGNERATKDE.........ADSES
  958-  989 (24.95/ 9.04)	DE.KEEPERDKERKHRKRHhssndelasDKDEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     105.73|      22|      22|      24|      45|       3
---------------------------------------------------------------------------
   11-   43 (35.33/17.83)	QP..................lwppsvgstppQGFGSSFPMQFRPAVST.QQG
   67-   93 (30.35/14.28)	MP.....................pghhsqipQ.F..SQPMQQFPPRPN.QPG
   95-  112 (21.34/ 7.87)	................................GILLSQAIQM.PFIQS.SMP
  133-  184 (18.71/ 6.00)	NPfsssytfapppfahalsglnmpsqvqsssQMHVPSFPSGGQPWLSSgSQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     124.75|      23|      23|     604|     626|       4
---------------------------------------------------------------------------
  520-  539 (25.78/13.06)	RRHRQRKAKEEFTK...MLEESK
  543-  558 (22.74/10.61)	SS.......TRWSKAVTMFEDDE
  604-  626 (40.23/24.72)	ETCGFIKVDTQWRKVQDLLEDDE
  632-  652 (18.16/ 6.91)	EKID..RLDIFQEYIRDLEKEDE
  664-  680 (17.84/ 6.65)	RTER..KNRDAFRK...MMEEQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.12|      24|      26|     361|     386|       5
---------------------------------------------------------------------------
  321-  347 (27.31/12.72)	TEQPSA...VTPvsSTPSStvSGVA..SSPVP
  361-  386 (38.06/26.83)	VSGSSAIpaVTP..AMPSS..SGVS..SPAVS
  388-  413 (23.76/10.07)	STGSAAL...AN..ASQTQ.mSGFEnlSPQVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     181.84|      47|      74|     726|     772|       6
---------------------------------------------------------------------------
  708-  732 (29.30/13.31)	...........VASN.......TSGSTPKD.......LFEDV....VEELEKQY
  733-  779 (80.19/49.12)	HEDKI.RVKDVVKSEKI...TISSTWTFEDFK...ATILEGIGSPSIHDVNLQL
  781-  823 (44.14/23.75)	FEDLIeRAKE..KEEKE...TKKRQRLAKDFTdklSTIKE.ITASSSWE.....
  824-  857 (28.22/12.54)	.ECKE.LVEDTSEFRAIgeeTISRA.VFEEYV...AWLQE..............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.59|      27|      27|     991|    1017|       7
---------------------------------------------------------------------------
  927-  953 (41.15/23.44)	EPKEERKREKDRERKHRKRHHIS..NDEV
  991- 1017 (46.48/27.57)	ESKRSRRHSSDRKKSKKLAHSPE..SDGE
 1019- 1045 (37.96/20.98)	RHKRHRRD..HRDGSRRNGGGYEelEDGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.13|      26|      66|     491|     516|       9
---------------------------------------------------------------------------
  491-  516 (44.64/30.36)	RYGALKTLGERKQAFNEYLMQRKKQE
  559-  584 (40.85/27.12)	RFKAVEREADREDLFRNYLVDLQKKE
  585-  599 (17.64/ 7.27)	R..A.KAQEEYRQNRLEY........
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12568 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELAEKSAGQVVQTGASTTSGVQVTAAVTSTEQPSAVTPVSSTPSSTVSGVASSPVPVTS
2) KERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKERDKEKERGNERATKDEADSESMDVTDNYEPKEERKREKDRERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDELASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGGYEELEDGELGEDGES
3) LSGLNMPSQVQSSSQMHVPSFPSGGQPWLSSGSQNTPVTAPTLLTNQ
4) MASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQFRPAVSTQQGQPFASSISASPQYRPVGQTSNAGMPPGHHSQIPQFSQPMQQFPPRPNQPGHGILLSQAIQMP
5) QSSMPQPQQVIPPLNSHMPGVSGAGNPFSS
292
862
150
1
108
350
1052
196
105
137










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELEDGEL
2) ILLSQAI
3) KKSKKLAHS
4) SRHKRHRRDHRD
1037
96
1003
1018
1046
102
1011
1029