<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12536

Description F-box-like/WD repeat-containing protein TBL1X
SequenceMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAATTTAATTTQATVSHQNPPKNGETTVNGDENGAHNINNHSKPMEIDGDVEIPSTKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSSGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDVCVHDLQAHSKEIYTIKWSPTGPATSNPSSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length522
PositionTail
OrganismTarsius syrichta (Philippine tarsier)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Tarsiiformes> Tarsiidae> Carlito.
Aromaticity0.07
Grand average of hydropathy-0.298
Instability index38.87
Isoelectric point5.45
Molecular weight56612.39
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12536
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     372.00|      40|      40|     330|     369|       1
---------------------------------------------------------------------------
  173-  202 (34.18/18.10)	..............LRGHESE...........VFICAWNPVS.........dlL.ASGS.GDSTAR
  221-  258 (43.52/25.21)	HCirEGGHDVP..S....NKD...........VTSLDWNSDG.........tlL.ATGS.YDGFAR
  259-  288 (31.29/15.90)	I...WTEDGNLASTLGQHKGP...........IFALKWNKKG..........nY............
  289-  340 (44.79/26.18)	IL..SAGVDKTTIIWDAHTGEakqqfpfhsapALDVDWQNNT..........tF.ASCS.TDMCIH
  341-  382 (62.79/39.89)	VC..RLGCDRPVKTFQGHTNE...........VNAIKWDPSG.........mlL.ASCS.DDMTLK
  383-  433 (58.90/36.93)	IW..SMKQDVCVHDLQAHSKE...........IYTIKWSPTGpatsnpssnimL.ASAS.FDSTVR
  437-  475 (50.47/30.51)	VE..RGVC...IHTLTKHQEP...........VYSVAFSPDG..........rYlASGS.FDKCVH
  476-  517 (46.05/27.14)	IW..NTQSGSLVHSYRG.TGG...........IFEVCWNARG........dkvG.ASASdGSVCV.
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12536 with Med16 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAAATTTAATTTQATVSHQNPPKNGETTVNGDENGAHNINNHSKPMEIDGDVEIPSTKA
110
170










Molecular Recognition Features






MoRF SequenceStartStop




1) FLVYRY
10
15