<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12472

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLQEGLEAGTPATGEKQLALCLQCLEKTLSSTKNRALLHIAKLEEASSWTAIEHCLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQLHRTGFPTIHALILLEGTMNLTGEMQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTQELKWTAFTYLKIPQVLVKLKKYFHGEKDFTEDVNSAFEFLLKLTPLLDKADQRCNCDCTNFLLQECNKQGLLSEANFASLVGKRTTDRDPQLKSSENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSGESTKTASVRALLFDISFLMLCHVAQTYGSEVILSETSSGEEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMNSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLERGWVDSRSIHILDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVQLLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPVEDMQPSKLMRLLSSNEDDANILSSPTDRSMNSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQDSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLRLPLGRQVAAKAIAAL
Length987
PositionTail
OrganismMesocricetus auratus (Golden hamster)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Myomorpha> Muroidea> Cricetidae> Cricetinae> Mesocricetus.
Aromaticity0.07
Grand average of hydropathy0.008
Instability index46.53
Isoelectric point6.32
Molecular weight110316.07
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12472
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.67|      54|     256|      61|     126|       1
---------------------------------------------------------------------------
   61-  126 (76.30/81.14)	LSYLKyaISsqmvsysSVLTAISKF....DDFSRD........LCVQALLDIMDMFCDrLSCHG.KAEECIGlcRALLS
  308-  374 (81.37/52.17)	FTYLK..IP.......QVLVKLKKYfhgeKDFTEDvnsafeflLKLTPLLDKADQRCN.CDCTNfLLQECNK..QGLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     284.06|      89|     240|     146|     249|       9
---------------------------------------------------------------------------
  146-  243 (138.88/108.10)	LEAGTPATGEKQLALCLQClEKTLSstknrallHIAKLEEASSWTAIEHCLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQLHRTGFPT
  393-  481 (145.18/93.39)	LKSSENANIQPNPGLILRA.EPTVT........NILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSGEST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.15|      18|     240|     279|     298|      10
---------------------------------------------------------------------------
  279-  298 (31.16/25.16)	PLFvlEIW.KACF..VGLIESPE
  521-  541 (28.99/16.77)	PFF..ETWmQTCMpeEGKILNPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.73|      51|     117|     614|     668|      11
---------------------------------------------------------------------------
  614-  668 (76.57/62.17)	LAVCAVAWLVAHV..RMLGLDEREKSLQMIrQLagpLYSENTLQFYNERVVIMNSIL
  734-  786 (85.15/55.36)	LHMGGVYWFCNNLikELLKETRKEHTLRAV.QL...LYSIFCLDMQQVTLVLLGHIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12472 with Med24 domain of Kingdom Metazoa
Unable to open file!