<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12431

Description tRNA pseudouridine(38-40) synthase
SequenceMGFARRAHIGLKALMENPVAAAAAASTAATASTAATASTAVRMSSDRASVALSAETYSSWDKHQLIERIRMLEQHQEQQVGAAVSMTQTQQQESLGTSASLEKAAVVVDPLPLETVSLPKKRQHQQQQQQQQRRRQPRPFDFALHRARHIALKISYQGDAYYGFSSATNDTVPTVEMFIFRALATAKLVPGETVCGWSRCGRTDKGVSAFEQVVSLWVRTALPSTNNTTRSTDTTDTPTGSTDTTDTIDTPMESTNNTMGSTIVTLDWTQVATLTEMMKTGQITALAPTLTTAPNPPSDIANIISHGIDYAPDLPIDKGSVPSSSTNCTDSVSEDPNSAELPYMNILNRLLPPDIRVLAWSPVDPLFDARFTCGHRKYNYFFDSAGLDLAAMKQAASLFQGTHDCRHICKIDPNKAARPEFFIRTIKECSIVSARDITGSDVLGPLSTTTTTTTTASNAVVNADNSRFHVLVVKGRAFLWHQVRNMMALLFLVGRGLESPLIVSDMLDLSRHPHNAGRPYYDMAPESPLVLVECGYPDCLVDWRVLDGNDPSAMRNACTTTAGMDLVAGNTARKTVSLKKPKELSNDVRVMAQLANLWRSSSIKELQLRTLIKRYVDLGSCLPTVADVQSDGGGGGSDATSVVIGTHAKGYVKLMDRSRCNSVQEAAQTKANNIAARLNSDGSAGQARPKSRNKTIKRPCIK
Length702
PositionTail
OrganismBatrachochytrium salamandrivorans
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Chytridiomycota> Chytridiomycota incertae sedis> Chytridiomycetes> Rhizophydiales> Rhizophydiales incertae sedis> Batrachochytrium.
Aromaticity0.05
Grand average of hydropathy-0.294
Instability index43.57
Isoelectric point8.67
Molecular weight76192.46
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
pseudouridine synthase activity	GO:0009982	IEA:InterPro
RNA binding	GO:0003723	IEA:InterPro

GO - Biological Process
pseudouridine synthesis	GO:0001522	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12431
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     241.77|      61|     174|     333|     395|       2
---------------------------------------------------------------------------
  333-  395 (105.73/91.94)	SEDPNSAELPYMNILNRllPPDIRVLAWSPVDPLFDARFTCGHRK...YNYFFDSAGLDLAAMKQA
  476-  508 (32.29/19.13)	.......................RAFLWHQVRNMMALLFLVGRGL...ESPLIVSDMLD.......
  510-  572 (103.76/83.23)	SRHPHNAGRPYYDMAPE..SPLVLVECGYP.DCLVDWRVLDGNDPsamRNACTTTAGMDLVAGNTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.07|      19|      32|     158|     176|       6
---------------------------------------------------------------------------
  158-  176 (34.16/22.20)	GDAYYGFS..SATNDTVPTVE
  191-  211 (30.91/19.40)	GETVCGWSrcGRTDKGVSAFE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12431 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ANNIAARLNSDGSAGQARPKSRNKTIKRPC
2) STNNTTRSTDTTDTPTGSTDTTDTIDTPMESTN
671
224
700
256










Molecular Recognition Features






MoRF SequenceStartStop




1) ARPKSRNKTIKRPCIK
2) FARRAHIGLKALM
3) VAAAAA
687
3
19
702
15
24