<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12431

Description tRNA pseudouridine(38-40) synthase
SequenceMGFARRAHIGLKALMENPVAAAAAASTAATASTAATASTAVRMSSDRASVALSAETYSSWDKHQLIERIRMLEQHQEQQVGAAVSMTQTQQQESLGTSASLEKAAVVVDPLPLETVSLPKKRQHQQQQQQQQRRRQPRPFDFALHRARHIALKISYQGDAYYGFSSATNDTVPTVEMFIFRALATAKLVPGETVCGWSRCGRTDKGVSAFEQVVSLWVRTALPSTNNTTRSTDTTDTPTGSTDTTDTIDTPMESTNNTMGSTIVTLDWTQVATLTEMMKTGQITALAPTLTTAPNPPSDIANIISHGIDYAPDLPIDKGSVPSSSTNCTDSVSEDPNSAELPYMNILNRLLPPDIRVLAWSPVDPLFDARFTCGHRKYNYFFDSAGLDLAAMKQAASLFQGTHDCRHICKIDPNKAARPEFFIRTIKECSIVSARDITGSDVLGPLSTTTTTTTTASNAVVNADNSRFHVLVVKGRAFLWHQVRNMMALLFLVGRGLESPLIVSDMLDLSRHPHNAGRPYYDMAPESPLVLVECGYPDCLVDWRVLDGNDPSAMRNACTTTAGMDLVAGNTARKTVSLKKPKELSNDVRVMAQLANLWRSSSIKELQLRTLIKRYVDLGSCLPTVADVQSDGGGGGSDATSVVIGTHAKGYVKLMDRSRCNSVQEAAQTKANNIAARLNSDGSAGQARPKSRNKTIKRPCIK
Length702
PositionTail
OrganismBatrachochytrium salamandrivorans
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Chytridiomycota> Chytridiomycota incertae sedis> Chytridiomycetes> Rhizophydiales> Rhizophydiales incertae sedis> Batrachochytrium.
Aromaticity0.05
Grand average of hydropathy-0.294
Instability index43.57
Isoelectric point8.67
Molecular weight76192.46
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
pseudouridine synthase activity	GO:0009982	IEA:InterPro
RNA binding	GO:0003723	IEA:InterPro
GO - Biological Process
pseudouridine synthesis	GO:0001522	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12431
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     241.77|      61|     174|     333|     395|       2
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  333-  395 (105.73/91.94)	SEDPNSAELPYMNILNRllPPDIRVLAWSPVDPLFDARFTCGHRK...YNYFFDSAGLDLAAMKQA
  476-  508 (32.29/19.13)	.......................RAFLWHQVRNMMALLFLVGRGL...ESPLIVSDMLD.......
  510-  572 (103.76/83.23)	SRHPHNAGRPYYDMAPE..SPLVLVECGYP.DCLVDWRVLDGNDPsamRNACTTTAGMDLVAGNTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.07|      19|      32|     158|     176|       6
---------------------------------------------------------------------------
  158-  176 (34.16/22.20)	GDAYYGFS..SATNDTVPTVE
  191-  211 (30.91/19.40)	GETVCGWSrcGRTDKGVSAFE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12431 with Med15 domain of Kingdom Fungi

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