<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12397

Description mediator of RNA polymerase II transcription subunit 33A-like isoform X2
SequenceMQTIDDVLHLTQIFGLQTCEPGVLMVELFFSIVWQLLDASLDDEGLLALPGEEKSAWLIRPQLHDMELDVHDSFGEKKTENSESLLKVNTAKAIEIIGQFLQNKKTERILCLALRNMPLQWAGFAQRLQLLGANSVVLGNAKLITPEVLLHWTSDKNKLLSQKGKTSQLEFRDVMSSGSLFSSAGQSHGVNWSALWLPIDLFLEDAMDGSQVLATSAVERLICLIKSLRAVNDTSWHNTFLGLWIAALRLIQRERDPSEGPVPRLDTCLCMLLSISTLAVTIIIEEEEVEPKEDDCSPSKSRDEKQSSGMCRKGLITSLQMLGEYESLLTPPQSIIAVANQAAAKAVMFISGVAVGNEYYDCASMNDAPINCSGNMRHLIVEACISRNLLDTSAYFWPGYVNALSSQVPRSASNQVVGWSSFMKGSPLTPSMVNALVATPASSLAEIEKIYEIAINGSGDEKISAASILCGASLVRGWYLQEHTALFISRLLLPPIPTDYSGSDSYLIDYAPFLNVLLVGISSVDCVQIFSLHGMVPLLAGQLMPICEAFGSSPPKSWILTSGEELTCHAVFSLAFTLLLRLWRFHHPPVENVKGDARPVGSQLTPEYLLLVRNSQLASFGKSPNDRLKARRLSKLLKFSLQPIFMDSFPKLKGWYRQHQECIASILSGLVPGAPVHQIVDALLTMMFRKINRGGQSLTSTTSGSSNSSGSANEEASIKLKVPAWDILEATPFVLDAALTACAHGRLSPRDLATGLKDLADFLPASFATIVSYFSAEVTRGIWKPAFMNGTDWPSPAATLSIVEQQIKKILAATGVDVPCLAVGGSSPAMLPLPLAALISLTITYKLDKASERLLALVGPALNSLAASCSWPCTPIIASLWAQKVKRWNDFLVFSASRTVFHHNSDAVVQLLKSCFTSTLGLGNSNGNNSGGVGTLLGHGFGSHVLGGMSPVAPGILYLRVHRSVRDVLFVVEEIVSLLMLSVRDIAVSGLPKEKAEKLKKTKYGMRYEQVSFASAMARVKLAASLGASLVWISGGSGLVQSLFKETLPSWFLSVHSVEREGVNYGGMVAVLRGHALAFFSVLCGTFSWGIDSSSSASKRRAKILDSYLEFLASALDGKFSIGCDWATWRAYVSGFVSLIVRCAPRWLLEVDLNVLTRLSNGLRQLNEEELGLELLESGGVNAMGAAAELIIEGGF
Length1196
PositionTail
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy0.193
Instability index41.25
Isoelectric point6.23
Molecular weight129747.49
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12397
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.09|      15|      23|     827|     841|       1
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  827-  841 (26.22/14.99)	SPAMLPLPLAALISL
  851-  865 (24.87/13.81)	SERLLALVGPALNSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.17|      25|      30|     240|     268|       2
---------------------------------------------------------------------------
  240-  268 (39.38/40.66)	FLGLWIAALRLIQRERDPSegpvPRLDTC
  272-  296 (39.78/28.39)	LLSISTLAVTIIIEEEEVE....PKEDDC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     142.46|      48|     160|     867|     920|       3
---------------------------------------------------------------------------
  867-  920 (72.38/77.01)	ASCSW..pcTPIIASLWAQKVKRWndFL.VFSASRTVFhhNSDAVVQLLKS...CFTSTL
 1028- 1083 (70.08/50.33)	ASLVWisggSGLVQSLFKETLPSW..FLsVHSVEREGV..NYGGMVAVLRGhalAFFSVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.36|      54|     165|       6|      60|       4
---------------------------------------------------------------------------
    6-   60 (88.77/57.71)	DVLHLTQIFGLQTCEPGVLMVELFFSIVWQLLDAsLDDEGLLALPGEEKSAWLIR
  173-  226 (89.59/54.31)	DVMSSGSLFSSAGQSHGVNWSALWLPIDLFLEDA.MDGSQVLATSAVERLICLIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.66|      29|     156|     301|     332|       5
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  301-  332 (49.35/38.38)	SRDEKQS..SGMCRKGLITS..LQmlgEYES.....LLTPP
  458-  495 (37.31/20.83)	SGDEKISaaSILCGASLVRGwyLQ...EHTAlfisrLLLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.05|      20|      24|     778|     797|       9
---------------------------------------------------------------------------
  778-  797 (40.33/28.27)	VTRGIWKPAFMNGTDWPSPA
  803-  822 (33.72/22.37)	VEQQIKKILAATGVDVPCLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     146.10|      40|     107|     560|     602|      12
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  560-  599 (69.78/33.43)	LTSGEELTCHAVFSLAFTLLLR...LWRFHHPPVENV.KG..DARP
  604-  631 (19.07/11.42)	............LTPEYLLLVRnsqLASFGKSPNDRL.K....AR.
  633-  675 (57.25/25.67)	LSKLLKFSLQPIFMDSFPKLKG...WYRQHQECIASIlSGlvPGAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12397 with Med33 domain of Kingdom Viridiplantae
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