<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12383

Description probable mediator of RNA polymerase II transcription subunit 26b
SequenceMAKNTGTLNKWRDYFETANSDIFNVIEYAVMVAAVDYPKEFKLRRDRIAELLFTCKVIRCFGCDKVELAIPNAANDDDKVFVSEFGGCDVKESKSSRGDDQIGMNVNQKISNYSYDEAEALTDEIEQESKTVGEVLRIKEIIDNFHDESDSDIYECLRRLQLMALSVETLKATEIGKSVNALRKHSSNNIRHLARTLVEDWKVMVEAWVNATTAFTENTPESMKASVVDEEEEGLPSPPLDDLAFISTQTTSMEFSQFFDGMDDDGNIQNTGEFNKNHENGRKDNPVRKQQFAESVTAAPKDRKVEKPKKQTSVVTPNKPFGGDSGPGRPIKPTFERKINNDEMKLLQKYDKGTIRPRHVPIQQNRLKCPDEDPDRVKLEATKRKLQERYQEAEKAKKQRTVQVMELNEIPKQGLRKQGPGHKNSHVRPGNHNRHWANGHR
Length441
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.889
Instability index41.62
Isoelectric point6.27
Molecular weight50286.88
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12383
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.75|      16|      21|     283|     302|       1
---------------------------------------------------------------------------
  286-  301 (26.48/22.09)	PVRKQQFAESVTAAPK
  304-  319 (26.27/ 7.38)	KVEKPKKQTSVVTPNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.35|      18|      21|     240|     257|       2
---------------------------------------------------------------------------
  214-  226 (14.70/ 6.29)	.........AFTENTPESMKAS
  239-  256 (32.43/22.46)	P....LDDLAFISTQTTSMEFS
  257-  275 (21.22/12.24)	QffdgMDDDGNI..QNTG.EFN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.23|      16|      22|      62|      80|       3
---------------------------------------------------------------------------
   62-   80 (24.28/18.07)	GCDKVElaiPNAANDDDKV
   87-  102 (28.95/14.49)	GCDVKE...SKSSRGDDQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.11|      17|      21|     123|     139|       4
---------------------------------------------------------------------------
  123-  139 (27.48/16.86)	DEIEQESKT.VGEVL.RIK
  143-  161 (22.64/12.80)	DNFHDESDSdIYECLrRLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.58|      14|      29|     167|     181|       6
---------------------------------------------------------------------------
  167-  181 (17.94/13.62)	VETLKATeIGKSVNA
  198-  211 (26.64/15.78)	VEDWKVM.VEAWVNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12383 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SQFFDGMDDDGNIQNTGEFNKNHENGRKDNPVRKQQFAESVTAAPKDRKVEKPKKQTSVVTPNKPFGGDSGPGRPIKPTFERKINNDEMKLLQKYDKGTIRPRHVPIQQNRLKCPDEDPDRVKLEATKRKLQERYQEAEKAKKQRTVQVMELNEIPKQGLRKQGPGHKNSHVRPGNHNRHWANGHR
256
441










Molecular Recognition Features






MoRF SequenceStartStop




1) EFSQF
2) GHKNSHVRPGNHNRHWANGHR
3) GRPIKPTFERKINNDEMKLLQKY
4) KQGLRK
254
421
328
412
258
441
350
417