<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12374

Description probable mediator of RNA polymerase II transcription subunit 26b
SequenceMAKSFGTLDKWRDYFRTANSDIFDIIEHAVMVAATDCPKEFKLRRDKIAEMLFTCKVTRCFGCDKVELAVPLANDDEGKNKNKSDFGGGFEAAGGSKESKANSSIDHHIELNVNQVSNYSYGEAEALTEVIEEETQTLGEVLRIKDIIDNNQHESAEVYECLRRLQLMALSVETLKATEIGKSVNALRKHSSKDIRHLSRTLIEDWKVLVDEWVNATAAFTGTESTPESMKVSVVDQEEEGLPSPPLDDLAFFAAQTTSMELSQFFDGMDDDGNPRNSGEFNENRGNGRKLSLDNQNNPVRKKQSADFFDAAPKESKGEQQKKQEAVIKKQTPVMRPNKPSGGDSGPGRPIKPVSEQKLKMSEMNFQQKSDKGTVQKRPVPSQLNKLRHSDEDAVQVKLEATKRKLQERYQEAENAKRQRTIQVMELHDIPKQGISNQGLGLKNPHMRPGNNNRHWANGRR
Length461
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.868
Instability index45.59
Isoelectric point6.42
Molecular weight51832.51
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12374
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.06|      21|      37|     272|     304|       1
---------------------------------------------------------------------------
  272-  304 (30.72/33.49)	DGNPRNS.GEFNEnrgngrklsldnQNNPVRKKQ
  310-  331 (31.34/13.91)	DAAPKESkGEQQK............KQEAVIKKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.34|      15|      17|     362|     378|       2
---------------------------------------------------------------------------
  362-  376 (26.72/17.99)	SEMNFQQKSDKGTVQ
  382-  396 (25.63/10.48)	SQLNKLRHSDEDAVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.15|      13|      16|     122|     136|       3
---------------------------------------------------------------------------
  122-  134 (19.37/16.12)	GEAEALTEVIEEE
  139-  151 (20.78/ 9.21)	GEVLRIKDIIDNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12374 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SQFFDGMDDDGNPRNSGEFNENRGNGRKLSLDNQNNPVRKKQSADFFDAAPKESKGEQQKKQEAVIKKQTPVMRPNKPSGGDSGPGRPIKPVSEQKLKMSEMNFQQKSDKGTVQKRPVPSQLNKLRHSDEDAVQVKLEATKRKLQERYQEAENAKRQRTIQVMELHDIPKQGISNQGLGLKNPHMRPGNNNRHWANGRR
263
461










Molecular Recognition Features






MoRF SequenceStartStop




1) PGRPIKPVSEQKLKMSEMNF
2) QKKQEAVIKKQTPVMRPNKP
347
321
366
340