<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12362

Description pre-mRNA-processing protein 40A-like isoform X2
SequenceMASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQFRPAVSTQQGQPFASSISASPQYRPIGQTPNAGMPPGHGQIPQFSQPMQQFPPRPSQPGHGILSSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTALSGLNMPSQVQSSSQMHVPPFPSGGQPWLSSGSQTTPVAAPTLLTSQQLSAIAPSVPAGTASQQNASDWQEYEAADGRRYYYNKITKQSSWEKPLELMTTLERADASTVWKEFTTADGRKYYYNKETKQSKWTIPEELKLARELAEISADQVVQTGASTISGVQVTAAVTSTEQPSAVTPASSTPSSTVSGVASSPVPVTSAVSDHASPLVVSGSSAIPAVTPAMPSSSGVSSPAVSGSTGSATLANASQKQMSGFENLSPQVASSLSGASIQDIEEAKKGMAVAGKVNVVPAEEKTTEEEPFLYATKQEAKNAFKALLEFANVESDWTWEQTMRVIINDKRYGALKTLGERKQAFNEYLMQRKKQEAEERRHRQRKAKEEFTKMLEESKELISSTRWSKAVTMFEDDERFKAVEREADREDLFRNYLVDLQKKERAKAQEEYRHNRLEYRQFLETCGFIKVDTQWRKVQDLLEDDERCSRLEKIDRLDIFQEYIRDLEKEDEEQRKLQKEQLRRTERKNRDAFRKMMEEQIAAGTLTAKTSWRDYCQMVKEYVAYQAVASNTSGSTPKDLFEDVVEELEKQYHEDKIRVKDVVKSEKITISSTWTFEDFKAAILEGIGSPSIHDVNLQLIFEDIIERAKEKEEKESKKRQRLAKDFTDKLSTIKEITASSSWEECKELVEDSSEFRAIGEETISRAVFEEYVAWLQEKAKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKEREKEKERGKERSTKDEADSESMDVTDNYEPKEERKREKDKERKHRKRHHISNDEVTSDKDEKVEPERDKERKHRKRHHSSNDEVASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGYEELEDGELGEDGES
Length1042
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.071
Instability index62.10
Isoelectric point6.14
Molecular weight118257.95
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12362
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     237.22|      31|      32|     926|     956|       1
---------------------------------------------------------------------------
  503-  526 (28.22/ 9.39)	.....RKK....QEAEERR.....H...RQR..KAKEEFTKML
  840-  868 (39.29/16.02)	EEYVAWLQ....EKAKEKE.....R...RREEEKAKKE..KEK
  869-  888 (29.70/10.28)	EEK.EKRK....DK..ERR.....E...KEREK........EK
  915-  948 (40.50/16.75)	.DNYEPKEerkrEKDKERK.....H...RKRHHISNDEVTSDK
  949-  977 (34.60/13.22)	DEKVEPER...........dkerkH...RKRHHSSNDEVASDK
  978- 1007 (31.36/11.27)	DEKEESKR....S....RR.....HssdRKKSKKLAHSPESDG
 1008- 1040 (33.56/12.59)	ESRHKRHR..rdHRDGSRR.....N...GGYEELEDGELGEDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.84|      38|      40|     200|     237|       2
---------------------------------------------------------------------------
  200-  237 (76.12/48.76)	TASQQNASD.WQEYEAADGRRYYYNKITKQSSWEKPLEL
  240-  278 (68.72/43.26)	TLERADASTvWKEFTTADGRKYYYNKETKQSKWTIPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     222.88|      27|      32|      73|      99|       3
---------------------------------------------------------------------------
    5-   26 (25.55/ 8.11)	..P..PPS..GPQPLW..PP....SvGS...T.PP..QGF.......
   28-   50 (23.54/ 6.96)	..S..SF....PM.QF........R.PAvstQ.QG..QPF...ASSI
   52-   72 (30.46/10.92)	ASP..QY...RPIGQT..PN....A.GM...P.PG..HG........
   74-   99 (48.27/21.09)	.IP..QFS..QPMQQF..PP....R.PS...Q.PG..HGI...LSSQ
  102-  137 (25.95/ 8.34)	QMPfiQSSmpQPQQVI..PP....L.NS...HmPG.vSGAgnpFSSS
  145-  172 (41.90/17.45)	NMP..SQV..QSSSQMhvPP....F.PS.....GG..QPW...LSSG
  347-  379 (27.21/ 9.06)	ASP..LVV..SGSSAI..PAvtpaM.PS...S.SGvsSPA...VSGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     307.26|      47|      66|     536|     582|       4
---------------------------------------------------------------------------
  436-  488 (50.16/22.15)	K...TTEEEPFL.YATK........................QE.....AK...NAFKALLE.....................fanveS..........DWTWEQTMrvIINDKRYGALKT
  489-  556 (41.96/17.45)	L...GERKQAFNEYLMQrkkqeaeerrhrqrkakeeftkmlEE.....SK...E.............................lissT..........RWSKAVTM..FEDDERFKAVER
  557-  624 (60.92/28.31)	E...ADREDLFRNYLVD........................LQ.....KK...ERAKAQEE.....yrhnrleyrqfletcgfikvdT..........QWRKVQDL..LEDDERCSRLEK
  625-  658 (41.14/16.98)	....IDRLDIFQEYIRD........................LE.....KE...D.....EE..........................Q..........RKLQ.........KEQLRRTER
  659-  701 (40.77/16.77)	K....NR.DAFR....................................K........MMEE..........................QiaagtltaktSWRDYCQM..VKEYVAYQAVAS
  702-  755 (33.14/12.40)	NtsgSTPKDLFEDVVEE........................LE.....KQyheDKIRVKDV.................vksekitisS..........TWT.......FED...FKAAIL
  756-  831 (39.18/15.86)	E...GIGSPSIHD..VN........................LQlifedII...ERAKEKEEkeskkrqrlakdftdklstikeitasS..........SWEECKEL..VEDSSEFRAIGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.79|      15|      28|     295|     311|       5
---------------------------------------------------------------------------
  295-  309 (26.77/20.10)	TGASTISG.....VQVTAAV
  324-  343 (22.03/ 8.44)	TPSSTVSGvasspVPVTSAV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12362 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKEREKEKERGKERSTKDEADSESMDVTDNYEPKEERKREKDKERKHRKRHHISNDEVTSDKDEKVEPERDKERKHRKRHHSSNDEVASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGYEELEDGELGEDGES
2) MASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQFRPAVSTQQGQPFASSISASPQYRPIGQTPNAGMPPGHGQIPQFSQPMQQFPPRPSQPGHGILSSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTALSGLNMPSQVQSSSQMHVPPFPSGGQPWLSSGSQTTP
3) VQVTAAVTSTEQPSAVTPASSTPSSTVSGVASSPVPVT
853
1
303
1042
177
340










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELEDGEL
2) KKSKKLAHS
3) SRHKRHRRDHRD
1027
994
1009
1036
1002
1020