<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12357

Description pre-mRNA-processing protein 40A-like isoform X3
SequenceMASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQQGQPFASSISASPQYRPIGQTPNAGMPPGHGQIPQFSQPMQQFPPRPSQPGHGILSSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTFAPPPFAQALSGLNMPSQVQSSSQMHVPPFPSGGQPWLSSGSQTTPVAAPTLLTSQQLSAIAPSVPAGTASQQNASDWQEYEAADGRRYYYNKITKQSSWEKPLELMTTLERADASTVWKEFTTADGRKYYYNKETKQSKWTIPEELKLARELAEISADQVVQTGASTISGVQVTAAVTSTEQPSAVTPASSTPSSTVSGVASSPVPVTSAVSDHASPLVVSGSSAIPAVTPAMPSSSGVSSPAVSGSTGSATLANASQKQMSGFENLSPQVASSLSGASIQDIEEAKKGMAVAGKVNVVPAEEKTTEEEPFLYATKQEAKNAFKALLEFANVESDWTWEQTMRVIINDKRYGALKTLGERKQAFNEYLMQRKKQEAEERRHRQRKAKEEFTKMLEESKELISSTRWSKAVTMFEDDERFKAVEREADREDLFRNYLVDLQKKERAKAQEEYRHNRLEYRQFLETCGFIKVDTQWRKVQDLLEDDERCSRLEKIDRLDIFQEYIRDLEKEDEEQRKLQKEQLRRTERKNRDAFRKMMEEQIAAGTLTAKTSWRDYCQMVKEYVAYQAVASNTSGSTPKDLFEDVVEELEKQYHEDKIRVKDVVKSEKITISSTWTFEDFKAAILEGIGSPSIHDVNLQLIFEDIIERAKEKEEKESKKRQRLAKDFTDKLSTIKEITASSSWEECKELVEDSSEFRAIGEETISRAVFEEYVAWLQEKAKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKEREKEKERGKERSTKDEADSESMDVTDNYEPKEERKREKDKERKHRKRHHISNDEVTSDKDEKVEPERDKERKHRKRHHSSNDEVASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGYEELEDGELGEDGES
Length1042
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-1.068
Instability index62.74
Isoelectric point6.09
Molecular weight118226.94
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12357
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.84|      38|      38|     200|     237|       1
---------------------------------------------------------------------------
  200-  237 (76.12/40.84)	TASQQNASD.WQEYEAADGRRYYYNKITKQSSWEKPLEL
  240-  278 (68.72/36.23)	TLERADASTvWKEFTTADGRKYYYNKETKQSKWTIPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     235.65|      36|      36|     852|     887|       2
---------------------------------------------------------------------------
  510-  549 (24.31/ 8.54)	...ERR..............H...RQRKAKE.....EFTKmlE...ES.....K.ELISSTRwskavtmfeDDE
  617-  658 (20.71/ 6.03)	ER.CSRlekidrldifqeyiR...DLEKEDE.....EQRK..L...QKEQLRRT.ER.................
  852-  887 (58.07/32.02)	EK.ERR..............R...EEEKAKK.....EKEK..E...EKEKRKDK.ERREKER.........EKE
  889-  918 (39.50/19.10)	ER.E................K...EKERGKE.....RSTK..D...EA....DS.ESMDVTD.........NYE
  919-  959 (41.30/20.35)	PKeERK..............R...EKDKERK.....HRKR..HhisNDEVTSDKdEKVEPER.........DKE
  961-  982 (23.49/ 7.97)	...........................KHRK.....RHHS..S...NDEVASDK.D..EKE............E
  983- 1023 (28.28/11.30)	SK.RSR..............RhssDRKKSKKlahspESDG..E...SRHKRHRR.DHRDGSR............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     270.11|      40|      40|      96|     135|       3
---------------------------------------------------------------------------
   16-   67 (46.04/20.05)	PsVGSTPPqgfGSSfpmQQGQPFASSIS..ASP.........qyrPIGQtpnAGMPPGHGQIP
   72-  110 (70.43/34.39)	P.MQQFPP...RPS...QPGHGILSSQA.I.QM............PFIQ...SSMPQPQQVIP
  111-  152 (65.42/31.44)	P.LNSHMP...GVS...GAGNPFSSSYT.FAPP............PFAQ.alSGLNMPSQVQS
  153-  197 (40.63/16.87)	S.SQMHVP...PFP...SGGQPWLSSGS.QTTPvaaptlltsqqlSAIA...PSVP.......
  325-  373 (47.60/20.96)	P..SSTVS...GVA...SSPVPVTSAVSdHASP...lvvsgssaiPAVT...PAMPSSSGVSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     209.75|      53|      65|     710|     774|       4
---------------------------------------------------------------------------
  433-  498 (62.36/34.83)	AEEKTTEEEpflyatKQE...AKNAFKA..llEFANVESDWTWEQTMRVIindkrygaLKTLGER..K....QA.FNE
  718-  774 (82.14/76.75)	ELEKQYHED......KIR...VKDVVKS....EKITISSTWTFEDFKAAI........LEGIGSPSIHdvnlQLIFED
  779-  841 (65.25/37.13)	AKEKEEKES......KKRqrlAKDFTDKlstiKEITASSSW..EECKELV...edsseFRAIGEETIS....RAVFEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.20|      10|      66|     559|     568|       5
---------------------------------------------------------------------------
  559-  568 (19.17/11.07)	DREDLFRNYL
  626-  635 (19.03/10.94)	DRLDIFQEYI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.00|      20|      21|     661|     681|       6
---------------------------------------------------------------------------
  661-  681 (29.15/24.62)	RDaFRKMMEEQIAAGTLTAKT
  684-  703 (34.84/24.74)	RD.YCQMVKEYVAYQAVASNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.95|      12|      25|     374|     385|       9
---------------------------------------------------------------------------
  374-  385 (20.47/12.23)	PAVSGSTGSATL
  401-  412 (19.48/11.27)	PQVASSLSGASI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12357 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKEREKEKERGKERSTKDEADSESMDVTDNYEPKEERKREKDKERKHRKRHHISNDEVTSDKDEKVEPERDKERKHRKRHHSSNDEVASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGYEELEDGELGEDGES
2) LSGLNMPSQVQSSSQMHVPPFPSGGQPWLSSGSQTTP
3) MASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQQGQPFASSISASPQYRPIGQTPNAGMPPGHGQIPQFSQPMQQFPPRPSQPGHGILSSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSY
4) VQVTAAVTSTEQPSAVTPASSTPSSTVSGVASSPVPVT
853
141
1
303
1042
177
130
340










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELEDGEL
2) KKSKKLAHS
3) SRHKRHRRDHRD
1027
994
1009
1036
1002
1020