<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12343

Description ATP-dependent DNA helicase Q-like 4A isoform X3
SequenceMSKDKLPKVNWTQHATAHENFSCQDKFLTSNFLFSLPTQKPCVREQMNARSMACQVRSATKLETEKAWKLLNSLKLSSKSYTRPGKTLPLTKDNKSFSQHSHNTHVLRASDVNYASARCTPLHQGVDENSEYSDTTRYAGNRFPSHSSGGAEIGKVVNRQNGADTSLANNSHSRGIGGISSNHAIGVSKTREYNNTCADGTDEDDILQNIDIDQIVEHYQTNCTPQPSVSRCPPITPFTDSKCLAGSEETNLPPELSLNCNHGLKLGLCPEALDHLQEMKDRLINISNDLLDNVSELSLEQVEMLRQERSQLKLQIQHLEKFLQTVSGNEERRMSQFSASTQTSAFQYETPRAGSSRIDPIRLDTQFHGYNESGGFGNWNSSSLSFDVTGGFGLSTAPVEREPYIPKYLEVKYTEGSNDKKWSSRDFPWTKKLEADNKKVFGNPSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQVNIPAAYLSSNMEWTEQQEILRELNSDVCKYKFLYVTPEKVAKSDVLLRHLESLHTRESLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPTVPVLALTATATMSVKEDVVQALGLANCIIFRQSFNRPNLRYSVIPKTKKCLEDIDNFIKKFHFDQCGIIYCLSRMDCERVAEKLQEYGHKAAFYHGSMEGAQRANIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLPSSCVLYYSYSDYIRVKHMISQGTVDQNSFGSGYGRSNVATSGRILETNVENLLRMVSYCENDVDCRRLLQLIHFGEKFESTNCRKTCDNCSKIQKCIEKDVTEVAKQLVELVKMTGQKFSSAHVLEVYRGSLSQYVKKHRHESLRLHGAGKHLAKGEASRVLRHLVTEDILVEDVKKSDLYGSVSSVLKVNESKAYNLFSGAQTMRLRLPSSVTQSKLGKFEATPAKVSLTSGKQSPPRTDPSAAPQSPVDTNLSAKLYTALRRLRTLLVKEAGDGVMAYHIFGDATMQQISIKVPRTTDELLDINGIGKVKIIKYGDRVLETIEATINEHKSVKTNSSGNDSTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVSKKQNKNPEVIDYRDLGYFDECMDGDIDFDETMMP
Length1175
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.533
Instability index42.41
Isoelectric point8.37
Molecular weight131573.30
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12343
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.51|      16|      23|     145|     165|       1
---------------------------------------------------------------------------
  145-  162 (24.80/27.80)	SHSSGGAEIGKvvNRQNG
  171-  186 (29.71/15.20)	SHSRGIGGISS..NHAIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.26|      11|      23|     918|     930|       2
---------------------------------------------------------------------------
  918-  930 (13.88/15.17)	GEASRVLRhlVTE
  944-  954 (18.38/10.92)	GSVSSVLK..VNE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.01|      36|      39|     802|     840|       3
---------------------------------------------------------------------------
  802-  840 (58.89/42.31)	TSGRileTNVENLLRMVSYCENDVD..CRRLLQLIHF.GEKF
  843-  881 (55.13/32.50)	TNCR...KTCDNCSKIQKCIEKDVTevAKQLVELVKMtGQKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.42|      35|      39|     370|     406|       4
---------------------------------------------------------------------------
  370-  406 (59.93/40.39)	YNESGGFGNWnsSSLSFDVTGGFGLSTAPVEREP.YIP
  413-  448 (61.49/35.67)	YTEGSNDKKW..SSRDFPWTKKLEADNKKVFGNPsFRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.31|      19|      30|     960|     978|       5
---------------------------------------------------------------------------
  960-  978 (33.24/20.61)	LFSGAQTMRLRLPSSVTQS
  992- 1010 (35.06/22.16)	LTSGKQSPPRTDPSAAPQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.50|      12|      38|     222|     233|       6
---------------------------------------------------------------------------
  222-  233 (25.48/16.18)	NCTPQPSVSRCP
  259-  270 (24.02/14.79)	NCNHGLKLGLCP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.81|      34|      38|     594|     631|       7
---------------------------------------------------------------------------
  597-  631 (51.38/47.08)	QKFpTVPVLALTA.TATMSVKEDV...VQALGLANC.IIF
  633-  671 (48.43/29.68)	QSF.NRPNLRYSViPKTKKCLEDIdnfIKKFHFDQCgIIY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12343 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQGVDENSEYSDTTRYAGNRFPSHSSGGAEIGKVVNRQNGADTSLANNSHSRGIGGISSNHAI
2) TINEHKSVKTNSSGNDSTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVSKKQNKN
123
1089
185
1147










Molecular Recognition Features






MoRF SequenceStartStop




NANANA