<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12342

Description ATP-dependent DNA helicase Q-like 4A isoform X2
SequenceMRTVNSAGGSMSKDKLPKVNWTQHATAHENFSCQDKFLTSNFLFSLPTQKPCVREQMNARSMACQVRSATKLETEKAWKLLNSLKLSSKSYTRPGKTLPLTKDNKSFSQHSHNTHVLRASDVNYASARCTPLHQGVDENSEYSDTTRYAGNRFPSHSSGGAEIGKVVNRQNGADTSLANNSHSRGIGGISSNHAIGVSKTREYNNTCADGTDEDDILQNIDIDQIVEHYQTNCTPQPSVSRCPPITPFTDSKCLAGSEETNLPPELSLNCNHGLKLGLCPEALDHLQEMKDRLINISNDLLDNVSELSLEQVEMLRQERSQLKLQIQHLEKFLQTVSGNEERRMSQFSASTQTSAFQYETPRAGSSRIDPIRLDTQFHGYNESGGFGNWNSSSLSFDVTGGFGLSTAPVEREPYIPKYLEVKYTEGSNDKKWSSRDFPWTKKLEADNKKVFGNPSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQVNIPAAYLSSNMEWTEQQEILRELNSDVCKYKFLYVTPEKVAKSDVLLRHLESLHTRESLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPTVPVLALTATATMSVKEDVVQALGLANCIIFRQSFNRPNLRYSVIPKTKKCLEDIDNFIKKFHFDQCGIIYCLSRMDCERVAEKLQEYGHKAAFYHGSMEGAQRANIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLPSSCVLYYSYSDYIRVKHMISQGTVDQNSFGSGYGRSNVATSGRILETNVENLLRMAWIVLKCLRSLLCNLIHFGEKFESTNCRKTCDNCSKIQKCIEKDVTEVAKQLVELVKMTGQKFSSAHVLEVYRGSLSQYVKKHRHESLRLHGAGKHLAKGEASRVLRHLVTEDILVEDVKKSDLYGSVSSVLKVNESKAYNLFSGAQTMRLRLPSSVTQSKLGKFEATPAKVSLTSGKQSPPRTDPSAAPQSPVDTNLSAKLYTALRRLRTLLVKEAGDGVMAYHIFGDATMQQISIKVPRTTDELLDINGIGKVKIIKYGDRVLETIEATINEHKSVKTNSSGNDSTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVSKKQNKNPEVIDYRDLGYFDECMDGDIDFDETMMP
Length1184
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.511
Instability index42.23
Isoelectric point8.57
Molecular weight132353.38
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12342
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     187.33|      60|      62|     868|     929|       2
---------------------------------------------------------------------------
  868-  929 (94.87/77.41)	IEKDVTEvaKQLVELVKMTGQKFSSAHVLEVYRGSLSQYVKKHRHESLRLHGA..GKHLAKGEA
  933-  994 (92.46/68.87)	LRHLVTE..DILVEDVKKSDLYGSVSSVLKVNESKAYNLFSGAQTMRLRLPSSvtQSKLGKFEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.51|      16|      23|     155|     175|       3
---------------------------------------------------------------------------
  155-  172 (24.80/26.15)	SHSSGGAEIGKvvNRQNG
  181-  196 (29.71/14.15)	SHSRGIGGISS..NHAIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.55|      12|      26|     230|     242|       4
---------------------------------------------------------------------------
  230-  242 (20.57/15.51)	QTNCTPQPSVSrC
  259-  270 (22.99/12.25)	ETNLPPELSLN.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     288.71|      94|     408|     610|     763|       6
---------------------------------------------------------------------------
  655-  763 (143.72/211.51)	IPKTKKCLEDIdNFIKKFHFDQCGiiyclSRMdCERVAEKLQEygHKAAFYHGSME.....GAQR...ANIQKQWSKDEINIICATvafgmGINKPDVRfVIHHSLPKSIE....GYHQEC
 1066- 1171 (144.99/85.80)	VPRTTDELLDI.NGIGKVKIIKYG.....DRV.LETIEATINE..HKSVKTNSSGNdstdsGKKRrnsINVQNANSKDEEDFTGST.....GRSKKRVS.KKQNKNPEVIDyrdlGYFDEC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.91|      24|      24|     520|     543|       7
---------------------------------------------------------------------------
  520-  543 (40.73/31.22)	I.PAAYLSSNMEWTEQQEI.LRELNS
  545-  570 (30.18/21.02)	VcKYKFLYVTPEKVAKSDVlLRHLES
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12342 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQGVDENSEYSDTTRYAGNRFPSHSSGGAEIGKVVNRQNGADTSLANNSHSRGIGGISSNHAI
2) TINEHKSVKTNSSGNDSTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVSKKQNKN
133
1098
195
1156










Molecular Recognition Features






MoRF SequenceStartStop




NANANA