<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12341

Description ATP-dependent DNA helicase Q-like 4A isoform X1
SequenceMRTVNSAGGSMSKDKLPKVNWTQHATAHENFSCQDKFLTSNFLFSLPTQKPCVREQMNARSMACQVRSATKLETEKAWKLLNSLKLSSKSYTRPGKTLPLTKDNKSFSQHSHNTHVLRASDVNYASARCTPLHQGVDENSEYSDTTRYAGNRFPSHSSGGAEIGKVVNRQNGADTSLANNSHSRGIGGISSNHAIGVSKTREYNNTCADGTDEDDILQNIDIDQIVEHYQTNCTPQPSVSRCPPITPFTDSKCLAGSEETNLPPELSLNCNHGLKLGLCPEALDHLQEMKDRLINISNDLLDNVSELSLEQVEMLRQERSQLKLQIQHLEKFLQTVSGNEERRMSQFSASTQTSAFQYETPRAGSSRIDPIRLDTQFHGYNESGGFGNWNSSSLSFDVTGGFGLSTAPVEREPYIPKYLEVKYTEGSNDKKWSSRDFPWTKKLEADNKKVFGNPSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQVNIPAAYLSSNMEWTEQQEILRELNSDVCKYKFLYVTPEKVAKSDVLLRHLESLHTRESLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPTVPVLALTATATMSVKEDVVQALGLANCIIFRQSFNRPNLRYSVIPKTKKCLEDIDNFIKKFHFDQCGIIYCLSRMDCERVAEKLQEYGHKAAFYHGSMEGAQRANIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLPSSCVLYYSYSDYIRVKHMISQGTVDQNSFGSGYGRSNVATSGRILETNVENLLRMVSYCENDVDCRRLLQLIHFGEKFESTNCRKTCDNCSKIQKCIEKDVTEVAKQLVELVKMTGQKFSSAHVLEVYRGSLSQYVKKHRHESLRLHGAGKHLAKGEASRVLRHLVTEDILVEDVKKSDLYGSVSSVLKVNESKAYNLFSGAQTMRLRLPSSVTQSKLGKFEATPAKVSLTSGKQSPPRTDPSAAPQSPVDTNLSAKLYTALRRLRTLLVKEAGDGVMAYHIFGDATMQQISIKVPRTTDELLDINGIGKVKIIKYGDRVLETIEATINEHKSVKTNSSGNDSTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVSKKQNKNPEVIDYRDLGYFDECMDGDIDFDETMMP
Length1185
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.531
Instability index42.17
Isoelectric point8.42
Molecular weight132534.36
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12341
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.51|      16|      23|     155|     175|       1
---------------------------------------------------------------------------
  155-  172 (24.80/24.19)	SHSSGGAEIGKvvNRQNG
  181-  196 (29.71/13.04)	SHSRGIGGISS..NHAIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.26|      11|      23|     928|     940|       2
---------------------------------------------------------------------------
  928-  940 (13.88/18.31)	GEASRVLRhlVTE
  954-  964 (18.38/13.21)	GSVSSVLK..VNE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.01|      36|      39|     812|     850|       3
---------------------------------------------------------------------------
  812-  850 (58.89/39.60)	TSGRileTNVENLLRMVSYCENDVD..CRRLLQLIHF.GEKF
  853-  891 (55.13/30.43)	TNCR...KTCDNCSKIQKCIEKDVTevAKQLVELVKMtGQKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.42|      35|      39|     380|     416|       4
---------------------------------------------------------------------------
  380-  416 (59.93/43.17)	YNESGGFGNWnsSSLSFDVTGGFGLSTAPVEREP.YIP
  423-  458 (61.49/38.12)	YTEGSNDKKW..SSRDFPWTKKLEADNKKVFGNPsFRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.31|      19|      30|     970|     988|       5
---------------------------------------------------------------------------
  970-  988 (33.24/20.04)	LFSGAQTMRLRLPSSVTQS
 1002- 1020 (35.06/21.54)	LTSGKQSPPRTDPSAAPQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.50|      12|      38|     232|     243|       6
---------------------------------------------------------------------------
  232-  243 (25.48/17.15)	NCTPQPSVSRCP
  269-  280 (24.02/15.69)	NCNHGLKLGLCP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.81|      34|      38|     604|     641|       7
---------------------------------------------------------------------------
  607-  641 (51.38/41.56)	QKFpTVPVLALTA.TATMSVKEDV...VQALGLANC.IIF
  643-  681 (48.43/26.16)	QSF.NRPNLRYSViPKTKKCLEDIdnfIKKFHFDQCgIIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.86|      14|      28|     747|     773|      10
---------------------------------------------------------------------------
  747-  760 (25.66/39.46)	VIHHSLPKSIEGYH
  776-  789 (25.20/ 6.35)	VLYYSYSDYIRVKH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12341 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQGVDENSEYSDTTRYAGNRFPSHSSGGAEIGKVVNRQNGADTSLANNSHSRGIGGISSNHAI
2) TINEHKSVKTNSSGNDSTDSGKKRRNSINVQNANSKDEEDFTGSTGRSKKRVSKKQNKN
133
1099
195
1157










Molecular Recognition Features






MoRF SequenceStartStop




NANANA