<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12328

Description mediator of RNA polymerase II transcription subunit 23-like isoform X1
SequenceMNTAKRNWRNKTQKRVTALNRELPPRNEQFVLDFGQLQSQFADQEQLRAVAESVLISLVIQCSSHAPHAEFLLFAICSLSSIGYINWDTFLPSLLSSVSSTEISASQGNQLSGAVSSANLTQSGLLPSSTAVASTSNFHSSNPASPLPTVHGIGSPVQSTAEPSSSAALSPMKSSDVNGTSQQSIAKVNLLTRDNAASSLRQICCKIILTGLDSSLKPGTHAEVFHHMLNWLINWDQKLHGVDEFDSAKYWKPDKALIEWLHSCLDVIWLLVENDKCHIPFYELLRSGLQFLENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTPRLLPQATASSSGEAVANMRYSPITYPSVLGEPLHGEDLAASIQKGSLDWERALRILKHALRNSPSPDWWRRVLLVAPCHRLHAQAPTPGAVFTSEMVCEAAIERIVELLKLTNSEINCWQEWLIFSDIFFFLVKSGCVDFVEFVDKLVLRLQEGDQQILRTNHVTWLLAQIIRVELVMNALNTDSRKVETTRKILSFHKEEKSSDPNNPQSILLDFISSCQNLRIWTLNTATREYLNNEQLQKGKQIDEWWRQVNKGERMMDYMKLDDRSVGMFWVVSYTMAQPACETVMHWLTSAGVTELLPGPTLQSNERLVVMREVSPLPISLLSGFSTNLCLKLAYQMEESMFSGQAVPSIAVVETYCRLMLISPHSLFRSLLTVTSPLFPPNIPSLVFNSLACHCIFFRTTFIPLSQ
Length746
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.08
Grand average of hydropathy-0.068
Instability index51.50
Isoelectric point6.16
Molecular weight83862.37
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12328
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     369.90|     119|     179|     148|     326|       1
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  148-  284 (175.07/222.61)	PTvhgIGSP...VQSTAePSSSAALSPMKSSDVngtSQQSIAKVNLLTRDNAASSLR.QICCKIILTGLDSSLKPGTHAEVFHHMLnwLINWDQKLHGVDEFDSAKY..........................WKpdkaliEWLHSClDVIWLLVENDkChIPFYEL
  329-  477 (194.83/113.67)	PT...FGTPrllPQATA.SSSGEAVANMRYSPI...TYPSVLGEPLHGEDLAASIQKgSLDWERALRILKHALRNSPSPDWWRRVL..LVAPCHRLHAQAPTPGAVFtsemvceaaierivellkltnseincWQ......EWLIFS.DIFFFLVKSG.C.VDFVEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.16|      12|      15|     112|     123|       2
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  112-  123 (20.00/11.62)	SGAV.SSANLTQS
  129-  141 (16.16/ 8.04)	STAVaSTSNFHSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.17|      32|     513|       1|      34|       4
---------------------------------------------------------------------------
    1-   34 (51.14/49.07)	MNTAKRnwRNKTQKRVTALNRE...LPPRNEQ.FVLDF
  515-  550 (46.03/34.52)	LNTDSR..KVETTRKILSFHKEeksSDPNNPQsILLDF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12328 with Med23 domain of Kingdom Viridiplantae
Unable to open file!