<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12317

Description U-box domain-containing protein 35-like
SequenceMPAFNYIRSPSRIKRALSWKETFITEEEWQSMEENDISKTEGQGTVQSPTSSVVAIAISGNKNSKYVVKWALDKFVPEGETRFMLLHVRPEITAVPTPMGNLIPIAQVREDVADAFRKEVELQASEKLLPYKTMFIRRKVQVGVVQIESNDVVNAIAGVVSKCSINKLVIGTSTPGLFSRGRNLSASISETAPTFCTVYAVSKGKLSSVRPSSYENNGAVIDDSSDTSSSSNNSTGQSFSSQGERTDHSSTSPASYSHLYSPTRKLQRYQSKSPTHHALQTLLHKRTNIGETIQSRTSSIDIGEAFQALSIKNNTKRANLNEVIHPRAMTIATGEAEDDKSCYFSSSGITDPNSLNSSFKKAKLDNQQWSTSQSSNSDAPTDSSSGSQVNINYDLEKLRIELKHIQGMYAIAQTEAIDASRKLNEFQKLRVDEANKLMEINLKEEEAKEFAEQEKLKCEAAKKEADYAMECAEREVEKRRAAESIANREARAKEKLEKSLILPLHHYQKFTWEEIMTASASFSEDLKIGMGSYGMVYKCYLHHTTAAVKVLHSTEAHRTKQFQQELEILSTIHHPHLLILLGACPERGCLVYEYMENGSLEDRLIRKNKTPPLAWFDRVRIAWEVASALVFLHYTKPKPIIHRDLKPANILLDHNLVSKIGDVGLSTMVHSDSSSAMTAYKDTSPVGTLCYIDPEYQRTGLVSTKSDVYAFGMVILQLLTAKRAIALAHMVEMAIEDNNLVELLDQEAGEWPIEETKELAVLAIKCTELRRRDRPDLKDEVLPALERLKEVADRARDLIYILSPSPSHFKCPILKEVMHDPCVAADGYTYDRKAIESWLKDNDHSPVTNSPLPHKQLLANYTLLSAIKEWKSGKH
Length875
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.449
Instability index50.83
Isoelectric point6.64
Molecular weight98015.08
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12317
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.76|      39|      59|     173|     213|       1
---------------------------------------------------------------------------
  173-  213 (57.44/53.10)	STPGLFS.RGRNLSASiSETAPTFCTVYAVSKgKLSSVRPSS
  234-  273 (64.31/48.04)	STGQSFSsQGERTDHS.STSPASYSHLYSPTR.KLQRYQSKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.86|      28|     300|     410|     479|       2
---------------------------------------------------------------------------
  440-  473 (40.33/90.59)	INLKEEEAKEFAEQEklkceaAKKEADYAMECAE
  741-  768 (47.53/12.86)	VELLDQEAGEWPIEE......TKELAVLAIKCTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.94|      35|     345|     320|     354|       3
---------------------------------------------------------------------------
  289-  319 (45.02/31.19)	IGETIQSRTS...SIDIGEAFQA....LSIKNNTKRAN
  320-  354 (59.15/43.61)	LNEVIHPRAM...TIATGEAEDDKSCYFSSSGITDPNS
  355-  386 (31.77/19.54)	LNSSFKKAKLdnqQWSTSQSSNSDAPTDSSSG......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.47|      37|     212|     616|     660|       4
---------------------------------------------------------------------------
  616-  660 (58.63/46.28)	FDRVRI.AWevasalvfLHYTKPKPIIHRDLKPANILLDHNLVSKI
  830-  867 (60.84/34.17)	YDRKAIeSW........LKDNDHSPVTNSPLPHKQLLANYTLLSAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.60|      19|      50|      14|      32|       5
---------------------------------------------------------------------------
   14-   32 (34.89/23.09)	KRALSWK.ETFITEEEWQSM
   65-   84 (30.71/19.48)	KYVVKWAlDKFVPEGETRFM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12317 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SSYENNGAVIDDSSDTSSSSNNSTGQSFSSQGERTDHSSTSPASYSHLYSPTRKLQRYQSKSPTHHALQTLLHKRTNIGETIQSRT
212
297










Molecular Recognition Features






MoRF SequenceStartStop




NANANA