<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12302

Description luminal-binding protein
SequenceMAGYLRRGSSLVVLAIVLFGCLSALSIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFTDSERLIGEAAKNQAAVNPERTIFDVKRLIGRKFEDKEVQRDMKLVPYKIVNKDSKPYIQVKIKDGETKVFSPEEISAMILTKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDNRALGKLRREAERAKRALSSQHQVRVEIESLFDGTDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLEKNQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGIAPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKERIDARNSLETYVYNMKNQINDKDKLADKLESDEKEKIETATKEALEWLDDNQSAEKEDYEEKLKEVEAICNPIITAVYQRSGGAPGGGSSEEEEDGHDEL
Length666
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.463
Instability index31.61
Isoelectric point5.11
Molecular weight73441.32
Publications
PubMed=24807620

Function

Annotated function Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12302
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.72|      16|      16|     186|     201|       1
---------------------------------------------------------------------------
  186-  201 (27.29/16.89)	AQRQATKDAGVIA.GLN
  203-  219 (20.42/10.92)	ARIINEPTAAAIAyGLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.25|      14|      21|      38|      57|       2
---------------------------------------------------------------------------
   38-   51 (26.89/25.32)	VIGIDLGT..TYSCVG
   60-   75 (23.36/ 7.27)	IIANDQGNriTPSWVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.74|      17|      21|     589|     609|       3
---------------------------------------------------------------------------
  593-  609 (27.65/20.40)	DKLESDEKEKIETATKE
  615-  631 (29.09/11.87)	DDNQSAEKEDYEEKLKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.79|      29|     259|     230|     258|       4
---------------------------------------------------------------------------
  230-  258 (52.17/30.85)	FDLGG......GTFDVSI.LTID.NGVFEVLSTNGDT
  491-  527 (34.62/18.20)	FDLTGiapaprGTPQIEVtFEVDaNGILNVKAEDKGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.00|      29|     197|     131|     179|       6
---------------------------------------------------------------------------
  131-  159 (47.14/18.81)	SK.PYIQVKIK...DGE..TKVFSPEEISAMILTK
  326-  350 (38.27/12.25)	SE.PLTRARFE...ELN..NDLFR....KTMGPVK
  373-  402 (17.58/21.43)	TRiPKVQQLLKdyfDGKepNKGVNPDEAVA.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.88|      14|      15|     101|     114|       7
---------------------------------------------------------------------------
   78-   91 (21.20/12.04)	DSERLIGEAAKNQA
  101-  114 (23.14/13.80)	DVKRLIGRKFEDKE
  118-  130 (21.54/12.35)	DMK.LVPYKIVNKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12302 with Med37 domain of Kingdom Viridiplantae
Unable to open file!