<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12298

Description heat shock 70 kDa protein-like
SequenceMATKEGKAIGIDLGTTYSCVGVWLNDRVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHNTVFDAKRLIGRRFTDPSVQSDMKLWPFKVLSGPGEKPMIEVSYKGEKKQFSAEEISSMVLNKMKETAENFLGFQVKNSVVTVPAYFNDSQRQATKDAGAISGMNILRIINEPTAAAIAYGLDKKSSRIGEQHVLVFDLGGGTFDVSVLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVTEFKRKNKKDLSGNARALRRLRTGCERAKRTLSSTTQTTIEVDSLFEGIDFYATITRARFEELCMDLFMKCMEPVEKCLRDGKIDKSQIHEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILTGEGDEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERARTRDNNLLGKFELSGIPPAPRGVPQINVTFDIDANGILNVTAEDKTAGVKNKITITNDKGRLSKDEIDRMVRDAERYKAEDEEVKKKVEAKNGLENYAYNMRNTIKDEKIASKLSSEDKEKIEKGVQETIEWLDKNQLAEVDELEDKLKELERICNPIIARMYQGGGGGGGAGGGVSMDDDQMPGGGTRGGASGTTGTEPKIEEVD
Length659
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.459
Instability index33.35
Isoelectric point5.24
Molecular weight72408.15
Publications
PubMed=24807620

Function

Annotated function Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12298
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.34|      28|      74|     501|     529|       1
---------------------------------------------------------------------------
  501-  529 (40.43/33.19)	GVKNKITITnDKGRLSK.DEIDRMVRDAER
  578-  606 (39.90/26.91)	GVQETIEWL.DKNQLAEvDELEDKLKELER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.22|      69|     265|     138|     207|       4
---------------------------------------------------------------------------
   53-  131 (95.72/70.03)	IGDAAKNQVAMNPhnTVF.DAKRLIGRrftDPSVQSDMKLwpFKVLSGPgekPMIEVSYKGEKKQFSAEEISSMVLNKMK
  138-  207 (109.50/86.39)	LGFQVKNSVVTVP..AYFnDSQRQATK...DAGAISGMNI..LRIINEP...TAAAIAYGLDKKSSRIGEQHVLVFDLGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.56|      13|      19|     614|     627|       5
---------------------------------------------------------------------------
  614-  627 (23.72/13.86)	RMyQGGGGGGGAGG
  635-  647 (27.83/11.97)	QM.PGGGTRGGASG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.24|      39|     286|     249|     288|       8
---------------------------------------------------------------------------
  249-  288 (58.64/42.90)	EFKRK..NKKDLSGNARALRRLRTGcERAKRTLSSTTQTTIE
  536-  576 (58.60/37.19)	EVKKKveAKNGLENYAYNMRNTIKD.EKIASKLSSEDKEKIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.32|      32|      79|     295|     326|       9
---------------------------------------------------------------------------
  295-  326 (58.41/33.41)	GIDFYATITRARFEELCMDLFMKCMEPVEKCL
  357-  374 (25.39/11.00)	..DFFNG......KELC.....KSINP.DEAV
  377-  408 (46.52/25.34)	GAAVQAAILTGEGDEKVQDLLLLDVTPLSLGL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12298 with Med37 domain of Kingdom Viridiplantae
Unable to open file!