<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12296

Description pre-mRNA-processing protein 40A-like
SequenceMTDMERADASTDWREFTSPQGKKYYYNKVTRKSKWKMPDEVKLARQGMKVDLVKGLGKERDSISHASDFGSISGVKTSSPSANGSPVSAQGAMSSPIAVAPVSNLPTIVASESSSLSGNISSLTIGAVEMQNSLEPASPAVATSEKNGTAVTLENSVATPVTSSEFPSAQDSIVYEDGVSLENTEEVKKDATISETGSVTPSEEKTVEPGPLVYESKAEAKSAFKILLESANIGSDWTWDQAMRAIINDRRYGALKSLGERKQAFNEYLSHKKKLEAEERRVKQKKAREDFRIMLEECKELAPSTRWSKAISIFEHDERFKAVERAKDREDLFEDYMEKLEKKERARALEEQKRNRVEYLEFLKSCDFIKASSQWRKVQDRLEDDERCSCLEKIDRLEIFQEYIRDLEREEEEHRKLRMDELRKAERKNRDEFRKLMEEHLAAGILNAKTNWRDYCIKVKDLPAYQAVSSNTSGPTAKDLFQDVFDELEKQYLDDKSRIRDAVRMAEIGLTSTWTLEDFKVAIAKDISSPPISDTNLKFVFEELLERAREREEKEAKRRKRLADEFYELLHTSKEITASSKWEDCKSIFGDRIMGEESFLLEIFDKFSSELKEKAKEKERKRQEDKARKEKERKDREKKKEKHRRDKDRGDKSRKERERTKKDGTDSDKADTYSFEEIKRLGSDRDKKHRKRHMSSFDDNENEKDHSRNSYRHDNDHKKSKQVDQHVWSSEVNSEGQHKKQKRDHRSGSHRDGDSEDHKDGEFGEDGEVR
Length770
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-1.147
Instability index45.28
Isoelectric point6.38
Molecular weight89114.22
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12296
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     111.74|      19|      19|     619|     637|       1
---------------------------------------------------------------------------
  414-  431 (27.71/11.38)	HRKLRMDELRKA.E......RKNRD
  619-  637 (32.68/14.79)	ERKRQEDKARKEKE......RKDRE
  641-  658 (29.66/12.72)	EKHRR.DKDRGDKS......RKERE
  692-  716 (21.69/ 7.26)	RHMSSFDDNENEKDhsrnsyRHDND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     413.43|      65|      65|     273|     337|       2
---------------------------------------------------------------------------
  203-  269 (70.08/36.99)	.....EEK.TV..EpgplvyesKAEAK..S..................A.FKILL.ESANIGSD.....WTWDQAMRAIIN....D.RRYGAL...KSLGE..........RKQAFNEYL
  273-  337 (107.78/60.97)	KKLEAEER.RV..K........QKKAR..E..................D.FRIMLEECKELAPS.....TRWSKAISIFEH....D.ERFKAV...ERAKD..........REDLFEDYM
  338-  404 (85.01/46.49)	EKLEKKERaRAleE........QKRNR..V..................E.YLEFLKSCDFIKAS.....SQWRKVQDRLED....D.ERCSCL...EKI.D..........RLEIFQEYI
  408-  485 (48.70/23.40)	EREE......................E..EhrklrmdelrkaerknrdE.FRKLMEE..HLAAGilnakTNW.RDYCIKVK....DlPAYQAVssnTSGPT..........AKDLFQDVF
  486-  545 (53.77/26.62)	DELE...K.QY..L........DDKSRirD..................A.VR..MA...EIGLT.....STWTL.............EDFK.V...AIAKDissppisdtnLKFVFEELL
  549-  599 (48.08/23.00)	R..EREEK.EA..K........RRKRL..A..................DeFYELLHTSKEITAS.....SKWEDCKSIFGDrimgE.ESF..............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.39|      31|      50|      59|      89|       3
---------------------------------------------------------------------------
   59-   89 (51.74/33.16)	ERDSISHA..SDFGSISGVKTSSPSANGSPVSA
   93-  125 (42.49/25.99)	MSSPIAVApvSNLPTIVASESSSLSGNISSLTI
  130-  151 (31.16/17.22)	MQNSLEPA..S.....PAVATS..EKNGTAV..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.12|      12|      19|     717|     729|       4
---------------------------------------------------------------------------
  717-  729 (18.68/13.20)	HKKSKQvDQHVWS
  738-  749 (22.45/11.74)	HKKQKR.DHRSGS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12296 with Med35 domain of Kingdom Viridiplantae
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