<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12292

Description U-box domain-containing protein 35-like isoform X3
SequenceMFCKLRLIKREKMWLPNNKGSPANRRGNGTGVVAIAIDKDKGSQYAIKWATDNLVNRGQTLVLVHVVTKPTSSSYGNCGGVHVVDGNLSAHGQNLEKQTKELFLTFHCFCTRKDVRCLDVILEDSDVTKALTEYVSSAAIQNLVLGASRHGFIRRLKVTDIPSTVSKGAPDFCTVYVISKSKISSVKNASRPAPMASPLYKQIQQLEEQVNSGGITPTARTRAIHAGSVVDRSQRRSFISDESKKIGSGRPSTDHTSSMLYHDGMDSGRISQISTSSDSSFGSERLGARGSELSSFNDFSSSSFETDDGEAEMRRLKMELQRTMDLYSTACKEALTAKQKSEELNVWRMEEEKRLEEARLAEEAAKLAAEKERDKCKVAMETAEAAQRLAELEAKRRVDAEMQALKEAEQKEKAFMNLGQGDFRYRRYSIEEIEEATHFFTDSLKIGEGGYGPVYKCYLDHTPVAIKILRPDAAQGRSQFQQEVEVLSRMRHPNMVLLLGACPEYGCLVYEYMANGSLEERLMRCGDKRSLSWQLRFRIAAEIATGLLFLHQTKPEPLVHRDLKPGNILLDHNYVSKISDVGLSRLVPPSTTEEVTQYRITSAAGTFCYIDPEYQQTGMLGVKSDVYSFGILLLQLVTAKPAMGITHYVSQCIETGEFKEVLDPSVPDWPIEEALTFAKLALQCAELRRKDRPDLGKVVLPELNRLRALTEENMGQLLIGGSASPSPSHSQASISQEISSEPQVHSGFSTKSVSNSSASQEKHSGSGDE
Length769
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.441
Instability index48.85
Isoelectric point6.83
Molecular weight85241.64
Publications
PubMed=24807620

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12292
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.99|      23|      28|     359|     385|       1
---------------------------------------------------------------------------
  335-  354 (17.60/ 6.07)	........LTAKQKSEELNVwRMEEEKR
  359-  385 (31.15/28.28)	RLAEeaakLAAEKERDKCKV.AMETAEA
  388-  409 (29.24/16.98)	RLAE....LEAKRRVDAEMQ.ALKEAE.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     160.13|      44|     496|     247|     292|       2
---------------------------------------------------------------------------
  213-  243 (31.67/ 9.98)	GGITP.TARTRAI..HAGsvVDrSQRRSFISDE............S..............
  247-  291 (74.95/39.92)	GSGRPSTDHTSSMLyHDG..MD.SGRISQISTS............SDSSFGSERLGARGS
  721-  768 (53.51/22.98)	GSASPSPSHSQASI.........SQE...ISSEpqvhsgfstksvSNSSASQEKHSGSGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.05|      19|      29|      26|      45|       3
---------------------------------------------------------------------------
   26-   45 (28.41/22.12)	RGNgTGVVAIAIDKDKGSQY
   57-   75 (32.63/20.15)	RGQ.TLVLVHVVTKPTSSSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.30|      13|      27|     416|     428|       4
---------------------------------------------------------------------------
  416-  428 (25.75/15.25)	MNLGQGDF..RYRRY
  444-  458 (20.55/10.82)	LKIGEGGYgpVYKCY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12292 with Med32 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) SFISDESKKIGSGRPSTDHTSSMLYHDGMDSGR
2) SHSQASISQEISSEPQVHSGFSTKSVSNSSASQEKHSGSGDE
237
728
269
769

Molecular Recognition Features

MoRF SequenceStartStop
1) EPQVHSGFSTKSVS
2) MFCKLRLIKREKMW
741
1
754
14