<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12285

Description pre-mRNA-processing protein 40A-like isoform X2
SequenceMPDEVKLARQSMKVDLVKGLGKERDSISHASDFGSISGVKTSPLSANGSPVSAQGAMSSPIAVAPVSNLPTIVASESSSLSGNISSLTIGAVEMQNSLEPASPAVATSEKNGTAVTLENSVATPVTSSEFPSAQDSVVYEDGVSLENTEEVKKDATVSETGSATPSEEKTVEPGPLVYESKAEAKSAFKILLESANIGSDWTWDQAMRAIINDRRYGALKSLGERKQAFNEYLSHKKKLEAEERRIKQKKAREDFRIMLEECKELAPSTRWSKAISIFEHDERFKAVERAKDREDLFEDYMEELEKKERARALEEQKRNRVEYLEFLKSCDFIKASSQWRKVQDRLEDDERCSCLEKIDRLEIFQEYIRDLEREEEEHRKLRMDEMRKAERKNRDEFRKLMEEHVAAGILNAKTNWRDYCIKVKDLPAYLAVSSNTSGPKAKDLFQDVFDELEKQIGLTSTWTLEDFKVAISKDISSPPISDTNLKFVFEELLERAREREEKEAKRRKRLADEFYELLHTSKEITASSKWEDCKSIFGDRIMGEESFLLEIFDKFISELKEKAKEKERKRQEDKARKEKERKDREKKKEKHRRDKDRGDKSRKERERTKKDGTDSEKADTYSFEEIKRLGSDRDKKHRKRHMSSFDDNENEKDHSRNSYRHDNDHKKSKQVDQHVWSSEVNSEGQHKKQKRDHRSGSLRDGDNEDHKDGEFGEDGEVR
Length718
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.109
Instability index46.14
Isoelectric point6.00
Molecular weight82868.37
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12285
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.38|      36|      39|     628|     666|       1
---------------------------------------------------------------------------
  628-  664 (59.07/26.27)	RLGSDRDKKHRKRHMSSFDDNENEkDHSRNSYRHDND
  681-  716 (56.31/17.91)	NSEGQHKKQKRDHRSGSLRDGDNE.DHKDGEFGEDGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.01|      34|      39|      40|      78|       2
---------------------------------------------------------------------------
   43-   78 (50.72/54.02)	PLSANGSPVSAqGAM........SSPiAVAPVSNLPTIVASESS
   79-  120 (49.29/32.52)	SLSGNISSLTI.GAVemqnslepASP.AVATSEKNGTAVTLENS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     462.40|      65|      65|     242|     306|       3
---------------------------------------------------------------------------
  167-  233 (61.18/24.12)	.........EEK.TV..EpgplvyesKAEAK.SAFKIL.L.E...SANIG.SDWTWDQAMRAIIN.D.RRYGAL...K..SL.GERKQAFNEYL
  237-  301 (104.12/45.42)	KKL.EA...EER.RI..K........QKKAR.EDFRIM.LEE...CKELA.PSTRWSKAISIFEH.D.ERFKAV...E..RA.KDREDLFEDYM
  302-  368 (83.17/35.03)	EEL.EK...KERaRAleE........QKRNR.VEYLEF.LKS...CDFIK.ASSQWRKVQDRLED.D.ERCSCL...E..KI..DRLEIFQEYI
  369-  449 (59.74/23.41)	RDL.EReeeEHR.KL..R.mdemrkaERKNR.DEFRKL.MEEhvaAGILN.AKTNW.RDYCIKVK.DlPAYLAVssnT..SG.PKAKDLFQDVF
  450-  515 (57.00/22.05)	DEL.EK.......QIglT........STWTL.EDFKVA.I.....SKDISsPPISDTNLKFVFEElL.ERARER...EekEA.KRRKRLADEFY
  516-  556 (51.70/19.42)	E.....................................lLHT...SKEIT.ASSKWEDCKSIF...G.DRIMGE...E..SF...LLEIFDKFI
  557-  614 (45.48/16.34)	SELkEKakeKER.KR..Q........EDKARkEKERKD.REK...KKE.K.H..RRDKD....RG.D.KSRKER...E..RTkKDGTD......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.90|      16|      31|     121|     136|       4
---------------------------------------------------------------------------
  121-  136 (28.06/19.24)	VATPVTSSEFPSAQDS
  151-  166 (26.84/18.08)	VKKDATVSETGSATPS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12285 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKEKERKRQEDKARKEKERKDREKKKEKHRRDKDRGDKSRKERERTKKDGTDSEKADTYSFEEIKRLGSDRDKKHRKRHMSSFDDNENEKDHSRNSYRHDNDHKKSKQVDQHVWSSEVNSEGQHKKQKRDHRSGSLRDGDNEDHKDGEFGEDGEVR
2) QNSLEPASPAVATSEKNGTAVTLENSVATPVTSSEFPSA
3) TEEVKKDATVSETGSATPSEEKTVEPGPLV
563
95
148
718
133
177










Molecular Recognition Features






MoRF SequenceStartStop




1) DQHVWSSEVN
2) DREKKKEKHRRDKDR
3) GEFGEDGEV
4) KADTYSFEEIKRL
5) QHKKQKRD
672
583
709
617
685
681
597
717
629
692